Honing the tools to identify clues to surviving cancer

INDIANAPOLIS -- Why do some individuals survive cancer while others with the same cancer succumb to their disease? A key to survival is buried deep within the individual's biological makeup.

Researchers from the Indiana University School of Medicine and the Regenstrief Institute for Health Care are developing the tools that may bring scientists closer to identifying that key through a grant of $7.4 million from the National Cancer Institute.

Drawing upon their long-established expertise in medical informatics, they will develop, organize and test secure databases with unidentifiable data which in the future will allow scientists to review, compare and contrast the pathology reports and the DNA and protein content of stored tissues from all Indianapolis hospitals.

Building this 'machinery' and organizing the data is a challenging task that involves developing a natural language process, eliminating duplications, instituting standardization, and 'scrubbing' the data to eliminate person and place identifiers, according to Clement McDonald, M.D., the study's principal investigator and a internationally known medical informatics pioneer.

When the five-year project is completed, Dr. McDonald hopes to have a tool that will allow other researchers to compare DNA, proteins, and other biological factors to determine differences between the same tissue with and without cancer, those tissues with primary cancers and metastiasis, and the differing effects of therapy. Dr. McDonald is distinguished professor and Regenstrief professor of health services research at the IU School of Medicine and director of the Regenstrief Institute for Health Care.

The new study will draw upon data from as many as 1.6 million pathology reports and six million tissue blocks from Indiana University Hospital, Riley Hospital for Children, Methodist Hospital (which together comprise Clarian Health), Community

Contact: Cindy Fox Aisen
Indiana University

Page: 1 2 3

Related medicine news :

1. NIAID launches program to improve medical tools against emerging infectious diseases
2. New tools help families and schools prepare for disasters
3. Adaptive optics technology provides powerful tools for eye doctors
4. New software helps design multi-task, jaw-like, surgical mini-tools
5. New tools for early cancer detection
6. Study shows promise in identifying kidney failure
7. Chemists identify immune system mechanism for methamphetamine binges
8. Forensic dentistry key in identifying victims of tsunamis, other disasters
9. Radiography used to identify teens with sleep apnea
10. Simple question from your doctor can help identify your risk for breast cancer
11. Auditory test to help identify learning impaired

Post Your Comments:

(Date:2/19/2019)... ARLINGTON, Va. (PRWEB) , ... February 19, 2019 , ... ... new member of the Board of Directors. , Claudia is the CEO and Co-Founder ... impact on the health and wellness of people and the planet. She is a ...
(Date:2/19/2019)... (PRWEB) , ... February 19, 2019 , ... ... years of medical experience to The Oncology Institute of Hope and Innovation. , ... he graduated magna cum laude. He received his medical degree from the University ...
(Date:2/19/2019)... ... February 19, 2019 , ... ... their newest release of their enrollment kit solution, called ONEkit™ 2.0. This new ... their new and existing customers. ONEkit is integrated with O’Neil’s Omni-channel system, allowing ...
(Date:2/19/2019)... ... February 19, 2019 , ... ... survivor and well-respected advocate for patient engagement, will deliver the luncheon keynote ... brings critical awareness of participatory medicine and empowering partnerships between patients and their ...
(Date:2/19/2019)... ... February 18, 2019 , ... U.S. Patent No. ... 10,195,147 titled, “Dry powder aspirin compositions with magnesium stearate,” protect the ASPRIHALE™ formulation ... three previously granted utility patents, two issued by the USPTO and one issued ...
Breaking Medicine News(10 mins):
(Date:2/19/2019)... Fla. (PRWEB) , ... February 19, 2019 , ... ... knowledge and professional experiences with students from kindergarten through 6th grade at the ... live specimens, life cycle, mosquito surveillance and control with an emphasis on what ...
(Date:2/19/2019)... ... February 19, 2019 , ... TopConsumerReviews.com recently gave its best-in-class 5 star ... prevent Lice. , Lice outbreaks are surprisingly common, especially in schools and other environments ... lice is not a sign of uncleanliness; in fact, lice prefer to live on ...
(Date:2/19/2019)... ... February 19, 2019 , ... ... Senior Vice President. Kunney, based in Atlanta, is an experienced IT leader ... that effectively integrate within the clinical setting. He works with hospitals, health ...
Breaking Medicine Technology:
Cached News: