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Hopkins Researchers Develop New Therapy For Autoimmune Disorders Such As Rheumatoid Arthritis And Lupus

e professor of oncology and director of Bone Marrow Transplantation at the Johns Hopkins Oncology Center. "We acquire immunity through vaccinations and exposure to organisms which teach immune cells to recognize and attack foreign bodies."

In people with autoimmune disorders, the immune system attacks its own tissues and organs and must be re-taught to differentiate between the body's own cells and foreign attackers. "This therapy is analogous to rebooting a computer--you wipe out the old information, then allow it to re-learn. The immune system that returns should function normally," says Jones.

While the researchers are optimistic about these results, they caution that additional research and a larger number of patients are necessary to confirm these findings. They are now expanding the study to include additional patients with severe autoimmune disorders.

In addition to Jones and Brodsky, other research participants included Michelle Petri, M.D., M.P.H., B. Douglas Smith, M.D., Eric J. Seifter, M.D., Jerry L. Spivak, M.D., and Chi V. Dang, M.D., Ph.D., of Hopkins, and Michael Styler, M.D. and Isadore Brodsky, M.D., of Hahnemann University.


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Contact: Vanessa Gatto
gattova@jhmi.edu
410-955-1287
Johns Hopkins Medical Institutions
15-Dec-1998


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