HOME >> MEDICINE >> NEWS
Hopkins begins human trials with donor adult stem cells to repair muscle damaged from heart attack

Researchers at Johns Hopkins have begun what is believed to be the first clinical trial in the United States of adult mesenchymal stem cells to repair muscle damaged by heart attack, or myocardial infarct.

The so-called Phase I study is designed to test the safety of injecting adult stem cells at varying doses in patients who have recently suffered a heart attack.

An estimated 7 million Americans alive today have suffered at least one heart attack and so are at greater risk for chronic heart failure, sudden cardiac death or another, potentially fatal, heart attack.

"This is an important milestone on the journey to better cardiovascular care and to realization of the promise of adult stem cell research," says lead study investigator and cardiologist Joshua Hare, M.D., professor of medicine at The Johns Hopkins University School of Medicine and its Heart Institute.

"Current approaches to cardiovascular disease can prevent heart attack or alleviate its after-effects, but they have not included repair of damage that leaves sizably dead portions of heart tissue as dangerous scars in the heart," says study co-investigator and cardiologist Steven Schulman, M.D., a professor at Hopkins and director of the coronary care unit at The Johns Hopkins Hospital.

Previous research in animals showed that when adult stem cells were injected directly into the heart muscle, heart function was restored to its original condition within two months. Last November, at the American Heart Association Scientific Sessions 2004, the Hopkins team showed, again in animal studies, that more than 75 percent of dead scar tissue disappeared after therapy, which produced mostly healthy, normal-looking heart tissue and left only a small trace of the heart attack.

The Phase I study is being conducted at Hopkins, with support from Baltimore-based Osiris Therapeutics, which developed the stem cell product. The study will involve 48 adu
'"/>

Contact: David March
dmarch1@jhmi.edu
410-955-1534
Johns Hopkins Medical Institutions
25-Mar-2005


Page: 1 2 3 4

Related medicine news :

1. Earlier use of prostate cancer vaccines urged by Hopkins scientists
2. Hopkins convenes consensus conference to develop blueprint for nationwide matching program
3. Johns Hopkins scientists receive presidential medals
4. Hopkins Institute for Global Tobacco Control receives elite recognition from PAHO/WHO
5. Hunt for autism genes to be led by Hopkins researchers
6. Most household cleaners remove peanut allergens, Hopkins study shows
7. Exercise Hypertension occurs when cells cant relax, Hopkins researchers find
8. Hopkins young researchers honored for their contributions
9. Hopkins researchers find MRI useful tool in diagnosing inflammatory bowel diseases in children
10. Hopkins Peter Agre receives 2003 Nobel Prize in chemistry
11. Hopkins researchers study heart defect that kills athletes

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:12/14/2018)... (PRWEB) , ... December 14, 2018 , ... The Parenteral ... the term beginning January 1, 2019. In the fall of 2018, PDA’s 10,500 members ... following candidates have been elected/appointed as Directors to the PDA Board of Directors for ...
(Date:12/14/2018)... CHICAGO (PRWEB) , ... December 14, 2018 , ... Bathing ... fact, nearly 80 percent of falls at home occur in the bathroom for seniors ... in the business of making bathing safer since 2005, manufacturing or distributing walk-in tubs ...
(Date:12/13/2018)... ... December 13, 2018 , ... Ross A. Clevens, MD, FACS is ... Fame, an honor recognizing the highest-rated and most active doctors on RealSelf , ... providers. Dr. Clevens has been named a “Distinguished Inductee,” a distinction reserved for the ...
(Date:12/13/2018)... ... December 13, 2018 , ... New research out of ... and after their diagnosis are significantly more likely to survive than those who are ... part of a cancer prevention and treatment strategy. The results were published in a ...
(Date:12/13/2018)... (PRWEB) , ... December 13, 2018 , ... Women’s Excellence ... more about services, and get their questions answered. Women’s Excellence is proud to ... months, live chat will also be available during evening hours. , “This is the ...
Breaking Medicine News(10 mins):
(Date:12/13/2018)... ... December 13, 2018 , ... ... Microsoft to help further our efforts in improving the quality of life for ... devices in combination with power of artificial intelligence (AI). , This new grant ...
(Date:12/10/2018)... ... 2018 , ... Parkstone Growth Partners (“Parkstone”) and BayView Dental ... (“Parkview Dental”), a dentist-founded dental growth and management partnership. Parkview Dental will be ... practice comprised of 16 dentists and hygienists across eight offices who provide general, ...
(Date:12/8/2018)... ... December 07, 2018 , ... Nationally, it is estimated ... have dental insurance benefits that are seriously lacking and make it challenging to get ... believes that dental care should be accessible and affordable to everyone, with or without ...
Breaking Medicine Technology:
Cached News: