HOME >> MEDICINE >> NEWS
Hopkins begins human trials with donor adult stem cells to repair muscle damaged from heart attack

Researchers at Johns Hopkins have begun what is believed to be the first clinical trial in the United States of adult mesenchymal stem cells to repair muscle damaged by heart attack, or myocardial infarct.

The so-called Phase I study is designed to test the safety of injecting adult stem cells at varying doses in patients who have recently suffered a heart attack.

An estimated 7 million Americans alive today have suffered at least one heart attack and so are at greater risk for chronic heart failure, sudden cardiac death or another, potentially fatal, heart attack.

"This is an important milestone on the journey to better cardiovascular care and to realization of the promise of adult stem cell research," says lead study investigator and cardiologist Joshua Hare, M.D., professor of medicine at The Johns Hopkins University School of Medicine and its Heart Institute.

"Current approaches to cardiovascular disease can prevent heart attack or alleviate its after-effects, but they have not included repair of damage that leaves sizably dead portions of heart tissue as dangerous scars in the heart," says study co-investigator and cardiologist Steven Schulman, M.D., a professor at Hopkins and director of the coronary care unit at The Johns Hopkins Hospital.

Previous research in animals showed that when adult stem cells were injected directly into the heart muscle, heart function was restored to its original condition within two months. Last November, at the American Heart Association Scientific Sessions 2004, the Hopkins team showed, again in animal studies, that more than 75 percent of dead scar tissue disappeared after therapy, which produced mostly healthy, normal-looking heart tissue and left only a small trace of the heart attack.

The Phase I study is being conducted at Hopkins, with support from Baltimore-based Osiris Therapeutics, which developed the stem cell product. The study will involve 48 adu
'"/>

Contact: David March
dmarch1@jhmi.edu
410-955-1534
Johns Hopkins Medical Institutions
25-Mar-2005


Page: 1 2 3 4

Related medicine news :

1. Earlier use of prostate cancer vaccines urged by Hopkins scientists
2. Hopkins convenes consensus conference to develop blueprint for nationwide matching program
3. Johns Hopkins scientists receive presidential medals
4. Hopkins Institute for Global Tobacco Control receives elite recognition from PAHO/WHO
5. Hunt for autism genes to be led by Hopkins researchers
6. Most household cleaners remove peanut allergens, Hopkins study shows
7. Exercise Hypertension occurs when cells cant relax, Hopkins researchers find
8. Hopkins young researchers honored for their contributions
9. Hopkins researchers find MRI useful tool in diagnosing inflammatory bowel diseases in children
10. Hopkins Peter Agre receives 2003 Nobel Prize in chemistry
11. Hopkins researchers study heart defect that kills athletes

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/19/2019)... ... ... Residents in long-term-care nursing facilities were prescribed fewer medications when treated by staff ... of U.S. men and women led by the staff at the Los Angeles ... The quality assurance study examined the high number of prescriptions ordered for long-term nursing ...
(Date:4/19/2019)... ... April 19, 2019 , ... The Patient Advocacy Community of ... Health Network-CVPH, Plattsburgh, NY with the 2019 Ruth Ravich Patient Advocacy Award in ... fellow patient advocates. Doyle was honored with the award at The Beryl Institute’s ...
(Date:4/18/2019)... ... 2019 , ... Swiss Pet company PerAnimal launches a new unique ... between human and animal while improving the overall wellness of pet companions. , All ... of experience. They are made by hand from organic Swiss herbal condensate and Swiss ...
(Date:4/18/2019)... Calif. (PRWEB) , ... April 18, 2019 , ... ... upscale dental practice in Beverly Hills that offers a full menu of cosmetic ... cosmetic treatments and sought-after expertise in biomimetic dentistry, which relies on minimally-invasive techniques ...
(Date:4/18/2019)... ... April 18, 2019 , ... WHAT:, Patients today have ... Through the rise of online review sites and healthcare-related searches on the web, ... making important purchasing decisions online. In order to elevate a health system’s reputation ...
Breaking Medicine News(10 mins):
(Date:4/18/2019)... ... April 18, 2019 , ... ... industry-leading OPTIMASE® portfolio of biobased enzymes for medical instrument cleaning applications. ... specific challenges faced by medical instrument cleaning customers,” said Sheril Vaidhyan, Global ...
(Date:4/17/2019)... ... ... employer do you feel overwhelmed by all of the decisions you make when it comes ... engage your employees? Do you have the budget for a best in class solution? Will ... SVP of Strategic Partnerships, Hodges-Mace and Jay Schmitt, Principal, Strategic Benefits Advisors ...
(Date:4/17/2019)... ... 17, 2019 , ... Knight Security’s patented KnightSentry technology achieved ... tool by Security Today magazine in its annual The Govies Government Security Awards ... this contest recognizing outstanding government security products. , Knight’s innovative KnightSentry platform continuously ...
Breaking Medicine Technology:
Cached News: