Hormone therapy may be most protective in women with healthiest blood vessels

WINSTON-SALEM, N.C. When it comes to protection against heart disease, women with the healthiest blood vessels may have the most to gain from estrogen replacement therapy, reported Mary S. Anthony, Ph.D., from Wake Forest University Baptist Medical Center in Atlanta today at the 51st annual scientific sessions of the American College of Cardiology.

In a study of monkeys, Anthony and colleagues found that animals in the earliest stages of atherosclerosis, the buildup of fatty deposits in the vessels, showed the most benefit from hormone therapy. The hormone was most effective at slowing the diseases progression when it was given at an early stage.

Applied to women, this means that estrogen replacement therapy may be less effective when arterial disease is advanced, said Anthony, assistant professor of public health sciences. This corresponds with two studies showing that in women with existing heart disease, hormone replacement does not slow the diseases progression or prevent heart disease events.

For the study, female monkeys were fed a high-fat diet for two years to cause atherosclerosis. The researchers then measured fatty lesions in the animals blood vessels and designated the animals into three groups based on their levels of vessel disease.

The ovaries of all monkeys were removed to induce menopause. For three years after menopause, half of the monkeys were treated with estrogen in doses comparable to what women typically take. The other animals got no hormone treatment. At the end of the three years, the researchers again measured fatty lesions in the animals vessels.

The measurements showed that animals treated with estrogen had less atherosclerosis overall than the untreated group. But, the most dramatic differences were seen in monkeys that had the healthiest arteries to start with.

In the group of monkeys with the lowest levels of vessel disease at menopause, fatty lesions were 85 percent smaller in the estrogen-treated

Contact: Karen Richardson
Wake Forest University Baptist Medical Center

Page: 1 2 3

Related medicine news :

1. Hormone therapy increases risk of urinary incontinence
2. Hormone therapy controversy raises drug safety issues
3. Endocrine Society and Hormone Foundation call for increased research
4. Hormone therapy may still offer important health benefits to postmenopausal women
5. Hormone may offer hope for treating some behavioral disorders
6. Hormone found to protect bones
7. Hormone released by bone marrow cells may hasten recovery from brain injury
8. Hormones increase side effects, complicate treatment decision for prostate cancer patients
9. Hormones and drugs that control blood pressure also control malaria infection
10. Hormone replacement therapy reviewing the evidence
11. Hormone prompts adult stem cells to differentiate into islet cells

Post Your Comments:

(Date:8/5/2020)... , ... August 05, 2020 , ... ... firm based in New York, to complete the “Top Doctor” survey. The mission ... A randomly selected sample of board-certified physicians and key medical leaders were asked ...
(Date:8/5/2020)... ... August 05, 2020 , ... In its often-heroic ongoing response ... Regardless of the obstacle - shortages of tests, ventilators and ICU beds; strained ... or postponement of all nonessential services - providers across the country have found ...
(Date:8/5/2020)... ... August 05, 2020 , ... ChronWell, a technology-enabled ... of Clinical Services and Myron Falchuk, M.D. as an Advisor, to further expand ... achieved incredible growth as demand for remote care management services soared amidst the ...
(Date:8/5/2020)... ... 05, 2020 , ... CentrAlert, Inc. today announced the launch of ... COVID-19 information. Know NOW!, which is available for Apple and Android ... one easy-to-use mobile application. , “When COVID-19 first hit, there was so much that ...
(Date:8/5/2020)... (PRWEB) , ... August 04, 2020 , ... ... care of children with Autism Spectrum Disorder (ASD) in Wisconsin, is delighted to ... Wisconsin . With the opening of their newest center, Total Spectrum now proudly ...
Breaking Medicine News(10 mins):
(Date:8/5/2020)... ... August 04, 2020 , ... Fifty six percent of older adults think ... effectively to a healthcare crisis like COVID-19, according to a new survey by The ... important issues for older voters this year,” says Mary Johnson, a Medicare, and Social ...
(Date:8/3/2020)... (PRWEB) , ... August 03, 2020 , ... ... Business Continuity Emergency Operations Planning services for small business owners. These ... unable to manage or communicate with their teams for 30-90 days as a ...
(Date:7/31/2020)... ... July 31, 2020 , ... As one of the most prominent and ... of Missouri City, TX, with a wide range of professional dental services for many ... dental facility that is not far from the previous clinic location. Dr. Simone Ellis’s ...
Breaking Medicine Technology:
Cached News: