HOME >> MEDICINE >> NEWS
Hormones increase side effects, complicate treatment decision for prostate cancer patients

SALT LAKE CITY, UTAH--A common treatment for some men with prostate cancer at risk of recurring may lead to prolonged survival, but a new study shows at what cost. In an oral presentation today at the 45th annual meeting of the American Society for Therapeutic Radiology and Oncology (ASTRO) in Salt Lake City, Utah, Steven J. Feigenberg, M.D., a radiation oncologist at Fox Chase Cancer Center, explained the increased risk of both urinary and gastrointestinal side effects experienced by men receiving hormonal therapy with radiation therapy. "Over the last few years, adjuvant hormonal therapy has demonstrated disease-free and overall survival benefits for patients with high risk prostate cancer," Feigenberg said. "Our study shows that the addition of hormones increased the risk of both gastrointestinal and genitourinary side effects. In addition, the side effects worsened the longer the hormones were administered."

For the study, researchers evaluated 1,204 men who were treated with radiation therapy (3-D conformal radiation therapy) between May 1989 and November 1998. Of these men, 942 did not receive hormones while 155 and 106 patients received short- and long-term hormone suppression (androgen deprivation), respectively.

"The only independent predictor of urinary side effects, including frequent urination, was the use of hormone therapy while the use of hormones was one of four independent predictors of GI-related side effects," explained Feigenberg. "Moderate to severe gastrointestinal side effects were recorded for 17 percent of patients not taking hormone therapy, while 18 percent of patients receiving short-term hormones and 26 percent of patients receiving long-term hormones reported GI problems five years after treatment."

The findings for genitorurinary side effects showed that 8 percent of patients not taking hormones reported serious side effects while 8 and 14 percent of patients taking short- and long-term hormones, respectively, h
'"/>

Contact: Karen Carter Mallet
k_carter@fccc.edu
215-728-2700
Fox Chase Cancer Center
21-Oct-2003


Page: 1 2

Related medicine news :

1. Hormones and drugs that control blood pressure also control malaria infection
2. Depression May Lower Your Sex Hormones
3. Morning Coffee Boosts Blood Pressure, Stress Hormones All Day
4. Study finds that coordinating care of chronically ill patients does not increase liability
5. Primary care office strategies may increase colon cancer screening
6. Health care report cards may increase racial/ethnic disparities in bypass operations
7. Vitamin E may not prevent cancer or cardiovascular events, but may increase risk for heart failure
8. Study shows acrylamide in baked and fried food does not increase risk of breast cancer in women
9. Postmenopausal breast cancer survivors at increased risk for bone fractures
10. Obesity among African-American stroke survivors increases risk factors for recurrent stroke
11. Computerized order entry systems can increase risk of medication errors

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/5/2020)... South Africa (PRWEB) , ... August 05, 2020 , ... ... Invest Africa , the leading trade and investment platform for Africa, announced that they ... is for YPO Africa and Invest Africa to support each other in their African ...
(Date:8/5/2020)... ... August 04, 2020 , ... MemoryCare.com , a comprehensive ... Best Memory Care Facilities in Austin, Texas. The guide identifies 14 memory care ... According to the Alzheimer’s Association , 5.6 million people aged 65 and ...
(Date:8/3/2020)... ... 03, 2020 , ... Evolution Labs announced today that St. ... district-wide, developed to help students navigate a range of issues related to Mental ... must provide their students with preventative lessons after recent studies of social media ...
(Date:8/3/2020)... ... 03, 2020 , ... The process uses needlepoint bipolar ionization ... Arena, the Phoenix airport, the Mayo Clinic, Ramstein Air Force Base, Harvard University, ... Solutions (GPS), the manufacturers of the system, most viruses and other particles in ...
(Date:7/31/2020)... ... July 31, 2020 , ... Leaders of the ... internal medicine site in Savannah, GA. Visitors included Moncef Slaoui, chief advisor, and ... federal government announced the OWS program to accelerate the development, manufacturing, and distribution ...
Breaking Medicine News(10 mins):
(Date:8/12/2020)... , ... August 12, 2020 , ... ... (ASHA) is offering advice for parents of the more than 1 million ... their children perform and adjust to new virtual and modified in-person learning environments. ...
(Date:8/11/2020)... , ... August 11, 2020 , ... RCare, Inc. (Response ... over the past 6 months. This has been largely due to new major product ... need during the pandemic. RCare designed and custom-built the Rapid Deployment Kit (RDK), a ...
(Date:8/7/2020)... ... 07, 2020 , ... Glewed TV, a leading video-on-demand (VOD) ... content, today announced a partnership with award-winning director Charles Mattocks to air Eight ... The first reality TV series of its kind, Eight Days first aired on ...
Breaking Medicine Technology:
Cached News: