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How the cellular 'garbage disposal' grinds to a halt to cause Batten disease

problems: frequent seizures, loss of the ability to speak or move, and mental retardation. Most patients die in their teens or 20s.

A biochemist who uses yeast to study basic biological processes, in the past few years Pearce's laboratory has grown to more than a dozen scientists focusing on Batten disease. Based on his findings, a Rochester team hopes to conduct the first clinical trial in search of a treatment for the disease. Pearce, an assistant professor in the Department of Biochemistry and Biophysics, also serves as the scientific adviser for the Batten Disease Support and Research Foundation and meets children with the disease, and their families, on an ongoing basis.

"When I began this research, I had just become a parent, and I was horrified to find out that such a disease is out there," says Pearce. "It's my goal to be able to offer these children and their families some relief from this terrible illness."


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Contact: Tom Rickey
trickey@admin.rochester.edu
585-275-7954
University of Rochester Medical Center
28-Jan-2004


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