HOME >> MEDICINE >> NEWS
Humble Planaria worm offers ideal model for drug withdrawal research

Through the humble Planaria worm, Temple University researchers hope to discover what happens when drug abusers who take more than one drug-a common practice-go into withdrawal. Their work, which is funded by a new $450,000, three-year grant from the National Institutes of Health, is expected to lead to a better understanding of how withdrawal is influenced by poly-drug abuse and someday to the development of better treatment.

"People who abuse drugs tend to abuse many different drugs, yet much of the current research in the field focuses on single drug abuse," explained primary investigator, Robert Raffa, Ph.D., professor of pharmacology at Temple University School of Pharmacy.

Typically, abusers take several drugs together to multiply the pleasurable effects or manage the undesirable effects-for instance, using alcohol with cocaine. Because each type of drug affects the body differently, withdrawal is more complicated when more than one is involved. It would be impossible to conduct controlled scientific research on human subjects, so scientists have sought out alternatives.

As a study subject, the Planaria worm, a type of flatworm known for its regenerative powers, has several qualities attractive to scientists. First, it has such simple biochemistry and it readily absorbs any chemical in which it is soaked. This simplicity makes it a clean, easy-to-use model. But despite this simplicity, the Planaria worm has a brain and spinal cord, both key to studying the effects of drug abuse and withdrawal. Furthermore, Planaria have the same types of neurotransmitter systems as humans and thus respond to dopamine, opioids, cocaine and cannabinoids.

"Planaria offer a clean and uncomplicated model. We don't have to worry about potential interference from other organs or organ systems, as would be the case in other animal models," said Raffa. "Plus, Planaria display amazing behaviors. They can even learn."

Some might reme
'"/>

Contact: Eryn Jelesiewicz
dobeck@temple.edu
215-707-0730
Temple University
29-Nov-2004


Page: 1 2

Related medicine news :

1. UCSF study offers insight into human circadian rhythms
2. Research offers hope of new treatments for liver damage
3. Portable system offers dialysis patients liberating changes
4. New laparoscopic hysterectomy offers quicker recovery time than traditional surgery
5. UIC offers new weight loss surgery for obese teens
6. COX-2 product offers good and bad news in test tube strokes
7. Clinical breast examination offers modest benefit to breast cancer screening program
8. Research offers hope of new treatments for liver damage plague
9. Herpes virus offers new hope in curing cancer
10. Panel offers recommendations for monitoring adverse events from dietary supplements
11. Improved acute lymphoblastic leukemia treatment offers hope for eliminating irradiation

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:9/22/2017)... ... September 22, 2017 , ... "Success Files," a short- ... Alzheimer’s. Alzheimer’s is a disease estimated to affect the lives of more than ... the Alzheimer’s Association, a leading voice in the fight for cure and research ...
(Date:9/22/2017)... ... September 22, 2017 , ... ... and create life. Although frozen embryos have a slight statistical advantage for live ... freezing is a wonderful opportunity for women undergoing medical treatment or who are ...
(Date:9/21/2017)... ... September 21, 2017 , ... SABRE is raising awareness about personal ... to the end of November. , The Chicago, Illinois, based self-defense brand has been ... them about the ease of taking their personal safety into their own hands. , ...
(Date:9/21/2017)... ... September 21, 2017 , ... Bill Howe Plumbing’s mission is to create an ... to the community. For over 37 years, they have operated with their mission at ... in San Diego. They were chosen as the Best San Diego plumber in ...
(Date:9/21/2017)... ... September 21, 2017 , ... Japanese Zen artist couple, Fumie and Kentaro ... 7th and 8th October at Miranda Kuo Gallery on Lower East Side, NYC. This ... Zen Kodo mat. Wanderlust , one of the largest US yoga online media ...
Breaking Medicine News(10 mins):
(Date:9/6/2017)...  Medical professionals are expected to continuously ... their patients. Medical simulations offer clinicians the ... Simulation provides a safe method for teaching ... refine techniques and build confidence, without putting ... such as augmented reality, will now provide ...
(Date:9/5/2017)... 5, 2017  Xyntek Inc. has announced another milestone in their continued growth ... to meet the growing demands of customer engagements regionally.  ... Xyntek's new Midwest office is located at 318 West Adams Street, Suite ... Xyntek's ... ...
(Date:9/1/2017)... , Sept. 1, 2017  Explorers Like Us ( https://explorerslikeus.com/ ... greatest aural experiences — and deliver these experiences as part ... help people feel and heal better. ... While nothing beats a walk, jog ... your mind, Life Environments™ is the next best thing when ...
Breaking Medicine Technology:
Cached News: