HOME >> MEDICINE >> NEWS
Hunt for autism genes to be led by Hopkins researchers

With a three-year, $3.2 million grant from the National Institute of Mental Health, Johns Hopkins scientists will lead the largest hunt for genetic contributors to autism, a neuropsychiatric condition whose causes are almost as mysterious today as when the condition was first described in 1943.

The researchers will apply new genome searching technologies to available samples and information from 465 families, including 979 individuals with autism, to identify genetic factors that contribute to the condition.

"Autism is quite likely to result from the combined effects of multiple, very subtle genetic changes that differ considerably from family to family, since no single reliable genetic cause has been found yet," says Aravinda Chakravarti, Ph.D., principal investigator of the project and director of the McKusick-Nathans Institute of Genetic Medicine at Hopkins. "We'll be looking for combinations of genetic mutations and extra or missing gene copies that are much less common, even in the affected group, than most scientists are used to considering. This is a huge undertaking."

Recent research suggests that as many as 1 of every 500 births is affected by autism, which is characterized by social and communication deficits and restricted and repetitive interests. Understanding the condition's genetic roots may reveal important clues to its biology, and hence targets for treating some of its effects or trying to prevent it.

"The molecular genetic study of autism provides one of the best scientific opportunities in medicine: the chance to identify the missing or abnormal signals that prevent full development of a small set of nerve cells in the brain," says project member Edwin Cook, M.D., director of the University of Chicago's Laboratory of Developmental Neuroscience and a child and adolescent psychiatrist who sees patients with autism. "Once we know the disrupted signals, we can begin the process of rational development of medical treatm
'"/>

Contact: Joanna Downer
jdowner1@jhmi.edu
410-614-5105
Johns Hopkins Medical Institutions
11-Oct-2004


Page: 1 2 3

Related medicine news :

1. Helping answer needs by developing specialists in autism
2. Effects of autism reach beyond language, new research suggests
3. Monkey pay-per-view study could aid understanding of autism
4. Mayo Clinic study suggests no link between autism and immunizations
5. Brains of people with autism recall letters of the alphabet in brain areas dealing with shapes
6. Brain inflammation found in autism
7. Brains immune system triggered in autism
8. MRI shows brain changes underlying language deficits in autism
9. Imaging studies clarify brain changes associated with language deficits in autism
10. National Academies news: vaccines and autism
11. Cincinnati childrens study links autism and immunologic disorders

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/13/2017)... ... October 13, 2017 , ... ... that offers insurance and financial preparation services, is providing an update on a ... organization. , Rock City Rescue is a locally recognized nonprofit that provides shelter ...
(Date:10/13/2017)... Las Vegas, Nevada (PRWEB) , ... October 13, 2017 , ... ... of 7® Hemp CBD Oil utilizing Purzorb™ technology. Applying the Purzorb™process to full spectrum ... CBD dose required and providing a CBD form that can be easily incorporated into ...
(Date:10/13/2017)... ... October 13, 2017 , ... The Visiting Nurse Association ... Featuring a collection of specialty vendors and unique items from across the nation, this ... health and wellness services offered by the VNA. The boutique will be open ...
(Date:10/13/2017)... (PRWEB) , ... October 13, 2017 , ... ... DevOps and Agile Software Development, has been awarded a contract by the Center ... Purchase Agreement (BPA) aims to accelerate the enterprise use of Agile methodologies in ...
(Date:10/12/2017)... New Orleans, LA (PRWEB) , ... October 12, 2017 , ... ... fitness centers in the U.S., announced today its plans to open a flagship location ... club will occupy the former Rooms To Go store next to Office Depot in ...
Breaking Medicine News(10 mins):
(Date:9/22/2017)... AVACEN Medical (AVACEN) announced that its CE-Marked ... those with the widespread pain associated with fibromyalgia in ... Essex, England commented, "I had ... no sleep at all, tremendous pain, with every movement ... [the AVACEN 100] enough, how this has and is ...
(Date:9/19/2017)... ZirMed Inc ., a recognized leader in cloud-based revenue cycle ... ranked #1 by its users for the seventh consecutive year ... ZirMed was recognized as the top-ranked end-to-end revenue cycle management ... 200 beds and holds one of the longest #1 ranking ... ...
(Date:9/18/2017)... , Sept. 18, 2017 ... fields of bioinformatics and immune engineering, today ... protective avian influenza A (H7N9) vaccine. ... related to seasonal influenza and presents a ... on prior exposure to be effective. Using ...
Breaking Medicine Technology:
Cached News: