HOME >> MEDICINE >> NEWS
Ibuprofen could reduce cardioprotective effect of aspirin

A research letter in this week's issue of THE LANCET suggests that the painkiller ibuprofen could diminish the well-known beneficial effects of aspirin on preventing cardiovascular disease.

Aspirin makes platelets (blood-clotting cells) less 'sticky', which is associated with fewer thromboses (clots). Aspirin therefore reduces the chance of heart attacks caused by coronary thrombosis and stroke (cerebral thrombosis). Previous laboratory research has suggested that ibuprofen interacts with aspirin to reduce this 'good' effect of aspirin on platelet stickiness.

Tom MacDonald and Li Wei from the Medicines Monitoring Unit (MEMO) at the University of Dundee, Ninewells Hospital& Medical School, UK, studied 7107 patients with cardiovascular disease who were discharged from hospital and who were taking prescribed low-dose aspirin. Within this group they compared the death rate (from any cause and from cardiovascular causes) of those patients taking prescribed aspirin alone with those taking prescribed aspirin and ibuprofen. They also compared mortality data for patients taking another common painkiller (diclofenac) and those taking any of the other Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) in addition to aspirin.

Individuals prescribed both aspirin and ibuprofen (187 patients) had about a doubling of risk of death from any cause and around a 75% increased risk of death from cardiovascular disease, compared with those prescribed aspirin alone. There was no increase in mortality risk for people prescribed aspirin in combination with diclofenac or other NSAIDs.

Tom MacDonald comments: "Although our findings are not conclusive, they do support the hypothesis that ibuprofen may reduce the benefits of aspirin in people with cardiovascular disease. Perhaps it would be prudent that such patients took an alternative painkiller at least until this issue is further clarified. Furthermore, we also know that aspirin and ibuprofen taken together i
'"/>

Contact: Joe Santangelo
j.santangelo@elsevier.com
212-633-3810
Lancet
13-Feb-2003


Page: 1 2

Related medicine news :

1. Charcoal and forest management could reduce greenhouse gas levels & save lives in Africa
2. Novel therapy tested in mice could chase away cat allergies
3. Costs of antidepressants could have funded effective alternatives
4. Emergency clopidogrel could save thousands of lives46,000-patient heart attack trial results
5. Blood pressure treatment could cut risk of strokes and heart attacks
6. Proteins found in urine of pregnant women could help diagnose preeclampsia
7. Three out of the four million newborn babies who die each year could be saved
8. Increasing physician volume requirement could improve mammogram accuracy, study concludes
9. Chemicals in apples could reduce the risk of breast cancer, Cornell study in rats suggests
10. Training could remove racial bias from police reactions
11. Test could improve detection of prion disease in humans

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:9/22/2017)... ... , ... “Fruit of the Spirit: “Love””: a delightful adventure of two ... “Fruit of the Spirit: “Love”” is the creation of published author, Halimah Jones, who ... five. Halimah is an avid writer, her inspiration for “Fruit of the Spirit: “Love”” ...
(Date:9/22/2017)... (PRWEB) , ... September 22, 2017 , ... ... preserve fertility and create life. Although frozen embryos have a slight statistical advantage ... , “Egg freezing is a wonderful opportunity for women undergoing medical treatment or ...
(Date:9/21/2017)... FL (PRWEB) , ... September 21, 2017 , ... 38-Year-Old ... Aesthetic Surgery Center in Naples, Florida is pleased to announce that Plastic Surgeon Kiranjeet ... Top 40 Under 40 is an annual award that was started in ...
(Date:9/21/2017)... CA (PRWEB) , ... September 21, 2017 , ... ... lunch and learn with Infinity Behavioral Health Services for professionals in the addiction ... a Commercial Payer Audit . , Insurance companies and state and federal ...
(Date:9/21/2017)... ... September 21, 2017 , ... ... communities, nine governmental public health departments have been awarded five-year accreditation status through ... that the benefits of being served by a PHAB-accredited health department now ...
Breaking Medicine News(10 mins):
(Date:9/7/2017)... 2017 NuvoAir (formerly called Pond Healthcare ... a partnership with Novartis Pharma AG to distribute NuvoAir,s spirometry ... the leading mobile spirometry platform and Novartis, commitment to address ... ... ...
(Date:9/6/2017)... TORONTO , Sept. 6, 2017 /PRNewswire/ ... new knowledge and skills while treating their ... for hands-on experience without involving patients. Simulation ... skills. Clinicians can carry out procedures, refine ... at risk. Integration of new technology, such ...
(Date:9/5/2017)... , Sept. 5, 2017 Sapheneia and ... DoseCheck solution. Scannerside DoseCheck is a third-party Vendor neutral ... CT scanners and allows compliance with current MITA standards. ... proprietary XR 29 DoseCheck solution is specifically designed to ... alerts of potential radiation doses over a predefined threshold. ...
Breaking Medicine Technology:
Cached News: