HOME >> MEDICINE >> NEWS
Improved Ritalin Offers Smaller Doses And Fewer Side Effects

Derivatives of Drug Also Show Potential To Block Effects of Cocaine

ANAHEIM, Calif., March 22 -- A new more effective form of the drug Ritalin (methylphenidate) that produces fewer side effects and has the potential to be used in anticocaine therapy could soon be available, according to research findings presented here today at the national meeting of the American Chemical Society, the world's largest scientific society.

Commonly prescribed to treat Attention Deficit/Hyperactivity Disorder (ADHD), especially in school-age children, Ritalin has an approximate $500 million annual market in the U.S. Estimates vary on the number of youngsters taking the drug, but published reports in the scientific literature indicate that possibly as many as three percent of the country's elementary and secondary students, about 1.5 million, are prescribed Ritalin.

Using a new synthesis developed in his lab, University of Pennsylvania chemist Jeffrey Winkler, Ph.D., and his research group were able to make analogues of Ritalin that he says "have never been prepared before." Additionally, he notes, "Some of those new compounds look like very interesting candidates as anticocaine therapies."

Being able to synthesize "chiral Ritalin" from inexpensive non-chiral starting materials is the key to the drug's improvement, says Winkler. Drug compounds generally have mirror images, known as being right and left handed, but often only one of the "hands" is biologically active, delivering the desired pharmacological agents. Drugs containing "both hands" are called racemic. If a drug can be made one-handed, or chiral, it generally means smaller doses are needed and it avoids any potential side effects that might be contributed from the other hand. Such is the case for Ritalin, says Winkler. "It means less side effects and also less drug would have to be taken," by only including the biologically active r
'"/>

Contact: Charmayne Marsh
y_marsh@acs.org
202-872-4445
American Chemical Society
23-Mar-1999


Page: 1 2

Related medicine news :

1. Improved acute lymphoblastic leukemia treatment offers hope for eliminating irradiation
2. Improved mood tied to better language ability
3. Improved procurement could more than double availability of life-saving transplant organs
4. Improved molecular beacons show promise for cancer detection, rapid viral diagnosis
5. Patient Satisfaction And Decision Making Quality Greatly Improved During Improved Medical Consultations, UCSF Researchers Report
6. Improved Fitness Lowers Mortality Risk Of Male Heart-Attack Survivors
7. Improved Medications Can Nip Allergy Season In The Bud
8. Secondary Prevention Of Heart Disease Should Be Improved
9. Cardiac Arrests Outside Hospital - Survival Could Be Improved By Better Public Awareness Of Symptoms
10. Combined Therapy Improved Care Of Patients With Type 2 Diabetes Proper Use Of New Oral Medications Evaluated
11. Knife-Less Brain Surgery Offers New Treatment Options

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/31/2020)... ... August 31, 2020 , ... In an effort to ... is donating 10 percent of each hotel room booked with a special new ... Chicagoland & Northwest Indiana (RMHC-CNI) , effective immediately. Donations will be applied to ...
(Date:8/29/2020)... ... ... When professor and author Randy Pausch was diagnosed with pancreatic cancer, he accepted ... melancholic, however, he put together a final lecture in Carnegie Hall in which he ... situation and turned it into something that inspired millions of people worldwide. This inclination ...
(Date:8/28/2020)... ... August 28, 2020 , ... ... subscription to a customized Lighthouse Health & Wellness mobile app and web-portal. NCPCV ... project. Motorola Solutions Foundation awards grants each year to organizations, such as Destination ...
(Date:8/28/2020)... ... August 28, 2020 , ... Ziegler, ... Health on its investment in Synchronous Health, a tech-enabled behavioral health and well-being ... strength of human empathy with artificial intelligence (AI) to increase access and quality ...
(Date:8/27/2020)... ... August 27, 2020 , ... The team at ... aesthetic and wellness retreat. The practice is centered on results and providing the ... , Designed to be a sanctuary for total body renewal and aesthetic ...
Breaking Medicine News(10 mins):
(Date:8/28/2020)... ANTONIO (PRWEB) , ... August 28, 2020 , ... ... and operator of primary care medical centers in Florida and San Antonio is ... for its South Texas medical centers. , In this capacity he will serve ...
(Date:8/27/2020)... ... August 27, 2020 , ... Austin Oral Surgery – an oral ... announce Dr. David Szalay, DDS, MD, has joined the practice. An accomplished oral and ... Pflugerville office, which is scheduled to open this fall. The new office is slated ...
(Date:8/27/2020)... , ... August 27, 2020 , ... Bridge To A ... Dr. Friedman is an adult and pediatric neuro-oncologist who serves on the Board of ... an educator at Duke University Medical School. , Internationally recognized, Dr. Friedman is a ...
Breaking Medicine Technology:
Cached News: