HOME >> MEDICINE >> NEWS
Indiana University researchers closer to helping hearing-impaired using stem cells

INDIANAPOLIS -- Researchers at Indiana University School of Medicine are several steps closer to the day when a profoundly deaf patient's own bone marrow cells could be used to let him or her hear the world.

The IU group, led by Eri Hashino, Ph.D., was able to transform, in the laboratory, stem cells taken from adult bone marrow into cells with many of the characteristics of sensory nerve cells -- neurons -- found in the ear. The results suggest that these adult stem cells could be used to treat deaf patients in the future, said Dr. Hashino, an associate professor and Ruth C. Holton Scholar in the Department of Otolaryngology -- Head and Neck Surgery.

The cells used in the research are called marrow stromal cells -- a type of stem cell from which fat, bone and cartilage normally develop.

"We were interested in marrow stromal cells because of their potential for use in autologous cell-based therapy," said Dr. Hashino, referring to cell transplantation in which a patient's own cells are used in treatment. The cells can be collected easily and kept alive in the laboratory until needed, she said.

Other researchers had previously shown that the marrow stromal cells could be induced to transform into neuronal cells, but it wasn't clear whether, or how, the cells could be further transformed into useful specialized neurons.

In a two-step process, Dr. Hashino and her colleagues first cultivated mouse marrow stromal cells with chemicals known to encourage stems cells to change into primitive neurons. The bone marrow cells took the shape and other characteristics of neurons. Next, they exposed the cells to two molecules that are secreted from nearby tissues of the ear during embryonic development. The two molecules -- known as Sonic hedgehog and retinoic acid -- together caused the marrow stromal cells to further develop into cells with many of the characteristics of auditory neurons, such as the presence of specific genes and proteins.
'"/>

Contact: Eric Schoch
eschoch@iupui.edu
317-274-7722
Indiana University
28-Mar-2005


Page: 1 2

Related medicine news :

1. Indiana a national leader in new federal funding for health information technology
2. Grant expands Indiana University-Kenya AIDS program
3. New Indiana University School of Medicine pediatrics program focuses on patient advocacy
4. Indiana University orthopaedic surgeon to share cartilage growth research results
5. High intensity focused ultrasound for prostate cancer investigated at Indiana University School of Medicine
6. Indiana University Cancer Center receives National Cancer Institute designation
7. Boston University team finds link between high cholesterol and better cognitive performance
8. University seeks recruits for arthritis study
9. University of Manchester awarded 826k for brain science and mental health research
10. $4 million grant boosts University of Michigan campaign for a new childrens hospital
11. Lead in the environment causes violent crime, reports University of Pittsburgh researcher at AAAS

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/1/2020)... NEW YORK (PRWEB) , ... April 01, 2020 ... ... personal protective equipment (PPE) to stay safe while treating Coronavirus-infected patients. , Staffers ... and sneezes that can transmit coronavirus. Earlier this week, The Wall Street Journal ...
(Date:4/1/2020)... ... April 01, 2020 , ... Global mobile data platform provider Zerion Software ... to new needs based on COVID-19. , As cases continue to rise across the ... , Zerion will extend support by offering free basic iFormBuilder accounts and forms - ...
(Date:3/30/2020)... SAN DIEGO (PRWEB) , ... March 30, 2020 ... ... to new and prospective patients, continuing its commitment to provide comprehensive and ... , Patients can use Achieve Medical Center’s UpDox platform for telemedicine services ...
(Date:3/28/2020)... ... March 27, 2020 , ... Suntuity AirWorks ( https://suntuityairworks.com ... is mobilizing their drone equipment and training personnel to help towns and cities ... level Matrice and Agras drones, Suntuity AirWorks is mobilizing their drone equipment and ...
(Date:3/28/2020)... ... March 27, 2020 , ... The construction industry is ... of the coronavirus. Operating under the designation as an essential business as modified ... environmental protection projects in the downstate New York region. , While certain projects ...
Breaking Medicine News(10 mins):
(Date:3/30/2020)... DIEGO (PRWEB) , ... March 30, 2020 , ... ... COVID-19 pandemic, Aspire Regenerative now offers telemedicine appointments in addition to ... to ensure that the safety and well-being of patients, health care professionals, and ...
(Date:3/28/2020)... ... ... TriageLogic, a leader in remote patient communication and nurse triage, announces a quick ... hospitals, medical organizations, and health centers can use for patient care during the COVID-19 ... a system that can be quickly deployed for staff and nurses to work remotely ...
(Date:3/27/2020)... ... ... Shady Grove Fertility (SGF) —home to more than 85,000 babies born—now offers new ... consults , thereby minimizing interruptions in access to fertility care during this pandemic and ... been to improve access to care. We’re pleased to be able to offer patients ...
Breaking Medicine Technology:
Cached News: