HOME >> MEDICINE >> NEWS
Infection, not lack of oxygen, plays larger role in premature infant brain injury

Researchers at Johns Hopkins have dispelled the widespread belief among obstetricians that, in premature infants, brain injury results from a lack of oxygen, also called hypoxia, when, in fact, infection plays a larger role.

"Infection plays a much larger role than lack of oxygen in brain injury among premature infants," said high-risk obstetrician Ernest Graham, M.D., an assistant professor at The Johns Hopkins University School of Medicine, and lead author of the study, presented at the 24th annual meeting of the Society for Maternal-Fetal Medicine and set for publication in the American Journal of Obstetrics and Gynecology online Oct. 25.

"To reduce the risk of brain injury in the premature neonate, physicians may have to pay more attention to infections that occur around the time of birth."

The injury to the premature brain white matter, known as periventricular leukomalacia (PVL), is a condition in which small, cyst-like regions of brain tissue die. PVL is the most common form of brain injury in premature infants and results in cerebral palsy in 60 percent to 100 percent of those who live to adulthood. It can only be identified by ultrasound, MRI scan or CT scan of the infant's brain.

As part of their analysis, the researchers reviewed the records of 150 cases of white matter injury in premature infants born at Hopkins from 1994 to 2001. Rates of PVL were assessed by ultrasound recordings taken at three different times after birth. Using control cases without brain injury and matched by length of pregnancy, the researchers studied several factors believed to play a role in causing brain injury, including multiple births, lack of oxygen, and the presence of infections.

Overall, the researchers confirmed previous research that showed in women who had had twins or triplets, subsequent infants were at higher risk for the subsequent development of brain injury.

However, to their surprise, the research
'"/>

Contact: David March
dmarch1@jhmi.edu
410-955-1534
Johns Hopkins Medical Institutions
24-Oct-2004


Page: 1 2

Related medicine news :

1. Small band of nurses plays key role keeping germ threats at bay
2. Food displays, food colors affect how much people eat
3. White blood cell plays key role in bodys excessive repair response to asthma
4. Research suggests how steroids cause diabetes and hypertension; liver plays critical role
5. Behavior plays key role in disease development and control, according to 10-year prospective review
6. Health plays a crucial role in California labor market, according to UCSF researchers
7. Sleep plays role in managing childhood chronic pain
8. Space plays havoc with your immune system
9. New type of anthrax vaccine moves into larger-scale trial at Saint Louis University
10. Study: growth hormone-deficient young adults need larger replacement doses than older adults
11. Higher education or larger brain size may protect against dementia later in life, new study finds

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:9/3/2020)... ... 03, 2020 , ... International Dark-Sky Association (IDA) recently bestowed ... controller. This advanced LED wireless dimming controller, along with the previously IDA approved ... sky against light pollution. Leo Smith, the Northeast Regional Director for IDA says ...
(Date:9/1/2020)... ... 01, 2020 , ... As fall and winter swiftly approach and many businesses ... has taken this time to expand and grow into a full-fledged natural health clinic ... Institute will be relaunching its brand new website, expanding its services menu and has ...
(Date:8/31/2020)... ... August 31, 2020 , ... ... 1,400 N95 face masks to medical first responders across the United States. Since ... donations of personal protective equipment (PPE) medical centers , hospitals , ...
(Date:8/31/2020)... ... 31, 2020 , ... The pandemic and topsy-turvy economic outlook continues to put financial strain on ... ways to trim the fat from our monthly expenses and put more into savings, if ... that you have a financial safety net in place in case something were to happen ...
(Date:8/29/2020)... ... 2020 , ... When professor and author Randy Pausch was diagnosed with pancreatic ... Rather than become melancholic, however, he put together a final lecture in Carnegie Hall ... took a negative situation and turned it into something that inspired millions of people ...
Breaking Medicine News(10 mins):
(Date:8/31/2020)... , ... August 31, 2020 , ... ... wellness-related technologies, today announced that they have invested $400,000 in PopBase, one of ... in collaboration with the Global Wellness Institute (GWI). , The competition was ...
(Date:8/28/2020)... ... , ... Dr. Mark Surrey has been in practice for over 25 ... professor in the Department of OBGYN at UCLA’s David Geffen School of Medicine. ... Society and is a Clinical Director of Fellowship Training for UCLA & Cedars Sinai ...
(Date:8/27/2020)... N.C. (PRWEB) , ... August 27, 2020 , ... Bleep ... football player and sleep apnea patient, is the company’s new spokesperson. , “In my ... football field. So, when I found the Bleep DreamPort it was a Bleeping no ...
Breaking Medicine Technology:
Cached News: