HOME >> MEDICINE >> NEWS
Infections in low-birth-weight infants are associated with impaired neurodevelopment and growth

The registry data were used to classify infants by type of infection, including uninfected (2,161); clinical infection alone (1,538); sepsis (1,922); sepsis and necrotizing enterocolitis (279); or meningitis with or without sepsis (193). Sepsis is an infection of the bloodstream, and necrotizing enterocolitis (NEC) is a severe intestinal disease linked to infection.

Overall, 41 percent of the assessed infants had at least one adverse neurodevelopmental outcome. Infants without infection were least likely to have adverse outcomes, while those with sepsis/NEC were most likely. Overall, 62 percent of the infants had weight, length, or head circumferences less than the 10th percentile. Significant differences for all the neurodevelopmental outcomes except hearing impairment were found between children in most infection groups and the uninfected group. Only infants who had sepsis or sepsis/NEC were at increased risk of hearing impairment.

The investigators considered several possible reasons for the detrimental effects of infections of neonatal infections on the brains of newborns. An inflammatory response by immune signaling proteins called cytokines, either in the fetus or amniotic fluid, reflecting an infection in utero, appears to increase the risk for neonatal brain injury. Newborns with infections also are at risk for circulatory or respiratory problems that could contribute to difficulties with regulation of blood flow in the brain. Interventions to reduce brain injury associated with infection could include earlier diagnosis, efforts to stabilize blood pressure and maintain adequate oxygen supply, and therapies to reduce systemic inflammation.

"As the mortality rate for extremely-low-birth-rate infants continues to decrease, we are increasing our efforts to assess and improve the long-term outcomes associated with prematurity," Dr. Stoll said. "Additional studies will be important to fin
'"/>

Contact: Holly Korschun
hkorsch@emory.edu
404-727-3990
Emory University Health Sciences Center
16-Nov-2004


Page: 1 2 3

Related medicine news :

1. Infections linked to mental decline in elderly
2. Holding Policy Is Cost-Effective Way To Further Protect Blood Plasma Supply From HIV And Other Infections
3. Antidepressants Can Lead To Mouth Infections
4. Antibiotic Prophylaxis Could Help Prevent Respiratory Infections in the Critically Ill
5. Guidelines Offer Ways To Curb Antibiotic-Resistant Infections
6. Researchers discover shift in organisms causing early-onset sepsis in low-birth-weight infants
7. UMaine study looks at infants and chronic nighttime crying
8. Hospital acquired infections present major problem for infants in developing countries
9. Cigarette smoke worsens respiratory infections in infants
10. Columbia researchers receive $3 million to combat genetic killer of infants & toddlers
11. Brain tumor with dismal prognosis in infants can be cured in older children

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/13/2017)... ... 2017 , ... Many families have long-term insurance that covers care for a ... waiver for care if the client has a cognitive impairment diagnosis. , “What ... is often waived, so the benefits from their insurance start immediately,” said Mechell Vieira, ...
(Date:10/13/2017)... ... ... Global Healthcare Management’s 4th Annual Kids Fun Run brought out many kids this ... by Global Healthcare Management’s CEO, Jon Letko, is aimed at getting kids excited about ... ages; it is a non-competitive, non-timed event, which is all about having fun and ...
(Date:10/13/2017)... ... 2017 , ... Coveros, a leader in agile coaching services ... by the Center for Medicare and Medicaid Services (CMS). The Enterprise Agile Transformation ... Agile methodologies in a consistent and high value manner across CMS programs. Coveros ...
(Date:10/12/2017)... ... October 12, 2017 , ... ... healthcare compliance program management, will showcase a range of technology and learning solutions ... Living (NCAL) Convention and Expo to be held October 14–18, 2017 at the ...
(Date:10/12/2017)... WAUSAU, Wis. (PRWEB) , ... October 12, 2017 ... ... formulated standard products to meet the demand of today’s consumer and regulatory authorities ... team of probiotic experts and tested to meet the highest standard. , ...
Breaking Medicine News(10 mins):
(Date:10/12/2017)... SAN DIEGO , Oct. 12, 2017   Divoti ... Medical Alert Jewelry up to the standard of the latest FDA ... (Launched: June 2017). Anyone in need of Medical ID ... Divoti Medical Alert Jewelry are engraved in terms of the ... ...
(Date:10/11/2017)... 2017  BioPharmX Corporation (NYSE MKT: BPMX) researchers were ... innovative way to use nonlinear optical imaging to confirm ... drugs. A ... show how researchers from BioPharmX and the Wellman Center ... a suite of imaging techniques in what is called ...
(Date:10/11/2017)... 11, 2017  True Health, a leader in ... effort during National Breast Cancer Awareness month to ... Research recently ... that more than 10 million American women are ... BRCA1 or BRCA2 and have not had testing. These ...
Breaking Medicine Technology:
Cached News: