HOME >> MEDICINE >> NEWS
Infections in low-birth-weight infants are associated with impaired neurodevelopment and growth

The registry data were used to classify infants by type of infection, including uninfected (2,161); clinical infection alone (1,538); sepsis (1,922); sepsis and necrotizing enterocolitis (279); or meningitis with or without sepsis (193). Sepsis is an infection of the bloodstream, and necrotizing enterocolitis (NEC) is a severe intestinal disease linked to infection.

Overall, 41 percent of the assessed infants had at least one adverse neurodevelopmental outcome. Infants without infection were least likely to have adverse outcomes, while those with sepsis/NEC were most likely. Overall, 62 percent of the infants had weight, length, or head circumferences less than the 10th percentile. Significant differences for all the neurodevelopmental outcomes except hearing impairment were found between children in most infection groups and the uninfected group. Only infants who had sepsis or sepsis/NEC were at increased risk of hearing impairment.

The investigators considered several possible reasons for the detrimental effects of infections of neonatal infections on the brains of newborns. An inflammatory response by immune signaling proteins called cytokines, either in the fetus or amniotic fluid, reflecting an infection in utero, appears to increase the risk for neonatal brain injury. Newborns with infections also are at risk for circulatory or respiratory problems that could contribute to difficulties with regulation of blood flow in the brain. Interventions to reduce brain injury associated with infection could include earlier diagnosis, efforts to stabilize blood pressure and maintain adequate oxygen supply, and therapies to reduce systemic inflammation.

"As the mortality rate for extremely-low-birth-rate infants continues to decrease, we are increasing our efforts to assess and improve the long-term outcomes associated with prematurity," Dr. Stoll said. "Additional studies will be important to fin
'"/>

Contact: Holly Korschun
hkorsch@emory.edu
404-727-3990
Emory University Health Sciences Center
16-Nov-2004


Page: 1 2 3

Related medicine news :

1. Infections linked to mental decline in elderly
2. Holding Policy Is Cost-Effective Way To Further Protect Blood Plasma Supply From HIV And Other Infections
3. Antidepressants Can Lead To Mouth Infections
4. Antibiotic Prophylaxis Could Help Prevent Respiratory Infections in the Critically Ill
5. Guidelines Offer Ways To Curb Antibiotic-Resistant Infections
6. Researchers discover shift in organisms causing early-onset sepsis in low-birth-weight infants
7. UMaine study looks at infants and chronic nighttime crying
8. Hospital acquired infections present major problem for infants in developing countries
9. Cigarette smoke worsens respiratory infections in infants
10. Columbia researchers receive $3 million to combat genetic killer of infants & toddlers
11. Brain tumor with dismal prognosis in infants can be cured in older children

Post Your Comments:
(Date:8/22/2014)... Natural Clear Vision , a how-to ... own vision from legally blind to perfect 20/20 vision has ... , “There is a huge portion of the population ... and most people just think that’s the way it will ... can be pretty risky at times,” reports Michaels. “This program ...
(Date:8/22/2014)... factor receptor (EGFR) mutations found in the circulating free ... cell lung cancer (NSCLC) patients correlates well with the ... tyrosine kinase inhibitor (TKI) therapy is approved for EGFR ... standard for determining mutation status is with DNA derived ... not available. A more abundant and less invasive source ...
(Date:8/22/2014)... August 22, 2014 Testosterone treatment ... in U.S. courts on behalf of men who ... use of prescription low testosterone therapies, Bernstein Liebhard ... claim was filed against Pfizer Inc. on July ... life-threatening heart issues due to his use of ...
(Date:8/22/2014)... -- An intensive effort to sterilize feral cats reduced the ... and euthanized, a new study reveals. "We investigated whether ... into animal control," Dr. Julie Levy, a professor of shelter ... said in a university news release. "Neutering a ... she explained, "so we wanted to pick a focused area ...
(Date:8/22/2014)... blockages in the kidney arteries may benefit patients ... trials, according to new recommendations for renal artery ... today by the Society for Cardiovascular Angiography ... Center,s Sahil Parikh, MD, Director, Interventional Cardiology Fellowship ... University School of Medicine was the lead author ...
Breaking Medicine News(10 mins):Health News:Natural Clear Vision: Review Exposes Kevin Richardson’s Program for Restoring Vision Naturally 2Health News:High concordance between EGFR mutations from circulating-free tumor DNA and tumor tissue in non-small cell lung cancer 2Health News:Testosterone Treatment Lawsuit News: New Filing Alleges Depo-Testosterone Caused Life-Threatening Heart Problems, Bernstein Liebhard LLP reports. 2Health News:Testosterone Treatment Lawsuit News: New Filing Alleges Depo-Testosterone Caused Life-Threatening Heart Problems, Bernstein Liebhard LLP reports. 3Health News:Testosterone Treatment Lawsuit News: New Filing Alleges Depo-Testosterone Caused Life-Threatening Heart Problems, Bernstein Liebhard LLP reports. 4Health News:Neutering Project Curbed Feral Cat Population 2Health News:UH Case Medical Center's Dr. Parikh authors SCAI paper on renal artery stenosis treatment 2Health News:UH Case Medical Center's Dr. Parikh authors SCAI paper on renal artery stenosis treatment 3
(Date:8/22/2014)... Aug. 22, 2014  Diplomat, the nation,s largest ... of two winners in the 2014 Innovations in ... LLC. The results of the competition were announced ... News. Diplomat was honored as ... & Training program. Through Diplomat University, the company ...
(Date:8/22/2014)... Aug. 22, 2014  As the Medical Affairs, role ... leaders in this area are exploring methods to develop ... Medical Affairs Consortium at Best Practices, LLC is designed ... insights about the key challenges they face. The consortium ... through three virtual roundtable discussions where leaders discuss key ...
(Date:8/22/2014)... 22, 2014 /CNW/ - On Aug. 20, at its ... Canadian Medical Association (CMA) voted on and approved a ... including medicinal cannabis. Bedrocan Cannabis Corp., a leading Canadian ... CMA motion. The CMA is quite right ... with smoking any plant material, including medicinal cannabis. While ...
Breaking Medicine Technology:Diplomat honored as a Top Innovator by Specialty Pharmacy News 2Best Practices' Medical Affairs Consortium Survey Has Achieved Strong Participation 2Bedrocan Canada Statement Regarding Canadian Medical Association Motion on Smoking Marijuana 2
Cached News: