HOME >> MEDICINE >> NEWS
Infections in low-birth-weight infants are associated with impaired neurodevelopment and growth

The registry data were used to classify infants by type of infection, including uninfected (2,161); clinical infection alone (1,538); sepsis (1,922); sepsis and necrotizing enterocolitis (279); or meningitis with or without sepsis (193). Sepsis is an infection of the bloodstream, and necrotizing enterocolitis (NEC) is a severe intestinal disease linked to infection.

Overall, 41 percent of the assessed infants had at least one adverse neurodevelopmental outcome. Infants without infection were least likely to have adverse outcomes, while those with sepsis/NEC were most likely. Overall, 62 percent of the infants had weight, length, or head circumferences less than the 10th percentile. Significant differences for all the neurodevelopmental outcomes except hearing impairment were found between children in most infection groups and the uninfected group. Only infants who had sepsis or sepsis/NEC were at increased risk of hearing impairment.

The investigators considered several possible reasons for the detrimental effects of infections of neonatal infections on the brains of newborns. An inflammatory response by immune signaling proteins called cytokines, either in the fetus or amniotic fluid, reflecting an infection in utero, appears to increase the risk for neonatal brain injury. Newborns with infections also are at risk for circulatory or respiratory problems that could contribute to difficulties with regulation of blood flow in the brain. Interventions to reduce brain injury associated with infection could include earlier diagnosis, efforts to stabilize blood pressure and maintain adequate oxygen supply, and therapies to reduce systemic inflammation.

"As the mortality rate for extremely-low-birth-rate infants continues to decrease, we are increasing our efforts to assess and improve the long-term outcomes associated with prematurity," Dr. Stoll said. "Additional studies will be important to fin
'"/>

Contact: Holly Korschun
hkorsch@emory.edu
404-727-3990
Emory University Health Sciences Center
16-Nov-2004


Page: 1 2 3

Related medicine news :

1. Infections linked to mental decline in elderly
2. Holding Policy Is Cost-Effective Way To Further Protect Blood Plasma Supply From HIV And Other Infections
3. Antidepressants Can Lead To Mouth Infections
4. Antibiotic Prophylaxis Could Help Prevent Respiratory Infections in the Critically Ill
5. Guidelines Offer Ways To Curb Antibiotic-Resistant Infections
6. Researchers discover shift in organisms causing early-onset sepsis in low-birth-weight infants
7. UMaine study looks at infants and chronic nighttime crying
8. Hospital acquired infections present major problem for infants in developing countries
9. Cigarette smoke worsens respiratory infections in infants
10. Columbia researchers receive $3 million to combat genetic killer of infants & toddlers
11. Brain tumor with dismal prognosis in infants can be cured in older children

Post Your Comments:
(Date:7/7/2015)... ... July 07, 2015 , ... An article published June ... how innovation and technology would be the “key factors” in the growth of ... accessibility and affordability, especially in emerging and growing markets. According to the compounding ...
(Date:7/7/2015)... BELLINGHAM, WA (PRWEB) , ... July 07, 2015 , ... ... set to break ground as early as Summer 2015 on a four-acre site in ... dollar project, with the support of city officials and other members of the local ...
(Date:7/7/2015)... , ... July 07, 2015 ... ... convenience stores throughout the Southwest, including Giant, Mustang, Sun Dial and Howdy’s, ... program, surpassing their original 2015 fundraising goal by nearly $100,000, to help ...
(Date:7/7/2015)... (PRWEB) , ... July 07, 2015 , ... ... Times highlights rumors about possible facial rejuvenation that have emerged about Hillary Clinton. ... U.S. Secretary of State looks more youthful than she has in some time ...
(Date:7/7/2015)... ... July 07, 2015 , ... Quadrino Law Group is pleased to announce the ... York 11747. The new facility is a state of the art building, located ... Quadrino, the firm's CEO and founder, said, "We are pleased to service our clients ...
Breaking Medicine News(10 mins):Health News:Recent Article on Pharmaceutical Innovation Highlights the Need for Creative Solutions to Common Problems, Says Medlife Pharmacy 2Health News:Recent Article on Pharmaceutical Innovation Highlights the Need for Creative Solutions to Common Problems, Says Medlife Pharmacy 3Health News:New Silverado Memory Care Community Receives Unanimous Approval from Design Review Board 2Health News:Western Refining Raises $524,286 to Help Send Kids with Neuromuscular Disease to MDA Summer Camp 2Health News:Western Refining Raises $524,286 to Help Send Kids with Neuromuscular Disease to MDA Summer Camp 3Health News:Recent Article on Hillary Clinton Plastic Surgery Speculation Illuminates the Reasons Many Professionals Explore Facial Rejuvenation, says Dr. J 2Health News:Recent Article on Hillary Clinton Plastic Surgery Speculation Illuminates the Reasons Many Professionals Explore Facial Rejuvenation, says Dr. J 3
(Date:7/7/2015)... July 7, 2015 BioRx, a Diplomat company (NYSE: ... a Top Workplace in 2015 based on a survey held ... Media Group and a Philadelphia -based research ... and was completed by employees across the Greater ... area, with topics ranging from workplace environment to overall organizational ...
(Date:7/7/2015)... 7, 2015 Hill-Rom,s recent announcement that ... in cash and stock means the company can ... to Kalorama Information. The healthcare market researcher said ... device and advanced wound care markets, and is ... lifting devices, and other healthcare equipment. Welch Allyn,s ...
(Date:7/7/2015)... --  ICD-10 Charts ( www.icd10charts.com ) announced today ... officially launched its newest line of ICD-10 preparation ... new 4 Step ICD-10 Implementation Plan.  Both of ... Charts resources and mobile apps, are available to ... the release of these resources, the company has ...
Breaking Medicine Technology:BioRx Named a Top Workplace in 2015 by Enquirer Media 2BioRx Named a Top Workplace in 2015 by Enquirer Media 3Kalorama: Hill-Rom Enters Monitoring Market with Welch Allyn Purchase 2Kalorama: Hill-Rom Enters Monitoring Market with Welch Allyn Purchase 3ICD-10 Charts Releases Revolutionary Free Solution for Complete ICD-10 Preparation 2ICD-10 Charts Releases Revolutionary Free Solution for Complete ICD-10 Preparation 3ICD-10 Charts Releases Revolutionary Free Solution for Complete ICD-10 Preparation 4
Cached News: