HOME >> MEDICINE >> NEWS
Infections in low-birth-weight infants are associated with impaired neurodevelopment and growth

The registry data were used to classify infants by type of infection, including uninfected (2,161); clinical infection alone (1,538); sepsis (1,922); sepsis and necrotizing enterocolitis (279); or meningitis with or without sepsis (193). Sepsis is an infection of the bloodstream, and necrotizing enterocolitis (NEC) is a severe intestinal disease linked to infection.

Overall, 41 percent of the assessed infants had at least one adverse neurodevelopmental outcome. Infants without infection were least likely to have adverse outcomes, while those with sepsis/NEC were most likely. Overall, 62 percent of the infants had weight, length, or head circumferences less than the 10th percentile. Significant differences for all the neurodevelopmental outcomes except hearing impairment were found between children in most infection groups and the uninfected group. Only infants who had sepsis or sepsis/NEC were at increased risk of hearing impairment.

The investigators considered several possible reasons for the detrimental effects of infections of neonatal infections on the brains of newborns. An inflammatory response by immune signaling proteins called cytokines, either in the fetus or amniotic fluid, reflecting an infection in utero, appears to increase the risk for neonatal brain injury. Newborns with infections also are at risk for circulatory or respiratory problems that could contribute to difficulties with regulation of blood flow in the brain. Interventions to reduce brain injury associated with infection could include earlier diagnosis, efforts to stabilize blood pressure and maintain adequate oxygen supply, and therapies to reduce systemic inflammation.

"As the mortality rate for extremely-low-birth-rate infants continues to decrease, we are increasing our efforts to assess and improve the long-term outcomes associated with prematurity," Dr. Stoll said. "Additional studies will be important to fin
'"/>

Contact: Holly Korschun
hkorsch@emory.edu
404-727-3990
Emory University Health Sciences Center
16-Nov-2004


Page: 1 2 3

Related medicine news :

1. Infections linked to mental decline in elderly
2. Holding Policy Is Cost-Effective Way To Further Protect Blood Plasma Supply From HIV And Other Infections
3. Antidepressants Can Lead To Mouth Infections
4. Antibiotic Prophylaxis Could Help Prevent Respiratory Infections in the Critically Ill
5. Guidelines Offer Ways To Curb Antibiotic-Resistant Infections
6. Researchers discover shift in organisms causing early-onset sepsis in low-birth-weight infants
7. UMaine study looks at infants and chronic nighttime crying
8. Hospital acquired infections present major problem for infants in developing countries
9. Cigarette smoke worsens respiratory infections in infants
10. Columbia researchers receive $3 million to combat genetic killer of infants & toddlers
11. Brain tumor with dismal prognosis in infants can be cured in older children

Post Your Comments:
(Date:8/27/2015)... , ... August 27, 2015 , ... Sunbelt® Bakery, maker ... fructose corn syrup, is changing the expectation of how protein bars should taste with ... taste unlike any other protein bar on the market today. , The new ...
(Date:8/27/2015)... ... August 27, 2015 , ... Healthpointe clinics are now ... Bernardino, and Orange County. , Designed to accommodate the busy lifestyles and ... all of its locations. Executive Physicals are scheduled so that busy professionals ...
(Date:8/27/2015)... ... August 27, 2015 , ... Standifer Insurance ... Birmingham Alabama, is launching a joint charity drive with the Meadow View Elementary ... qualify for assistance programs, and many lack the simple supplies necessary for a ...
(Date:8/27/2015)... ... August 27, 2015 , ... A study conducted in Italy suggests that it ... to chemotherapy. Surviving Mesothelioma has just posted an article on the new research. ... Milan treated mesothelioma cells with different concentrations of the chemotherapy drug cisplatin. ...
(Date:8/27/2015)... ... , ... When hiking in hot, dry weather, the three things that must ... legs and the eyes. Of the three, the eyes are the most frequently neglected ... about accelerated evaporation, dehydration and dry eye. Hiking dry eye will be the topic ...
Breaking Medicine News(10 mins):Health News:Sunbelt® Bakery Changes the Expectations of How Protein Bars Should Taste with the Introduction of Its New Protein Delights 2Health News:Sunbelt® Bakery Changes the Expectations of How Protein Bars Should Taste with the Introduction of Its New Protein Delights 3Health News:Healthpointe Now Offering Executive Physicals 2Health News:Standifer Insurance Group Initiates Charity Drive to Provide School Supplies for Underprivileged Meadow View Elementary Students 2Health News:Standifer Insurance Group Initiates Charity Drive to Provide School Supplies for Underprivileged Meadow View Elementary Students 3Health News:Scientists Say Enzymes May Influence Chemotherapy Response in Mesothelioma, According to Surviving Mesothelioma 2Health News:Hiking Can Cause Dry Eye in Long, Hot, Dry Summer of 2015 but Is Preventable 2Health News:Hiking Can Cause Dry Eye in Long, Hot, Dry Summer of 2015 but Is Preventable 3
(Date:8/27/2015)... Aug. 27, 2015  MiMedx Group, Inc. (NASDAQ: ... human amniotic tissue and patent-protected processes to develop ... Wound Care, Surgical, Orthopedic, Spine, Sports Medicine, Ophthalmic ... corrected the multiple inaccuracies in the press release ... the recent rulings from the Patent Trial and ...
(Date:8/27/2015)... 27, 2015 NorthStar Anesthesia , one of ... has been selected by Mercy, based in Toledo, ... of their hospitals:  Mercy St. Vincent  Medical Center and ... Mercy St. Charles  Hospital in Oregon ... . "As we looked to create ...
(Date:8/27/2015)... Mass. and TORONTO , ... ) (OTCQB: GNBT) today announced the issuance of a ... Company,s proprietary buccal insulin spray product.  The white paper ... of the Company,s stockholders by Dr. James H. ... The white paper may be viewed online on the ...
Breaking Medicine Technology:MiMedx Corrects Inaccuracies In MTF Press Release Regarding The Recent Rulings From The Patent Trial And Appeal Board 2MiMedx Corrects Inaccuracies In MTF Press Release Regarding The Recent Rulings From The Patent Trial And Appeal Board 3MiMedx Corrects Inaccuracies In MTF Press Release Regarding The Recent Rulings From The Patent Trial And Appeal Board 4Four Mercy Hospitals in Northwest Ohio Select NorthStar Anesthesia 2Generex Announces Issuance of Buccal Insulin White Paper 2Generex Announces Issuance of Buccal Insulin White Paper 3Generex Announces Issuance of Buccal Insulin White Paper 4
Cached News: