HOME >> MEDICINE >> NEWS
Inhibiting Growth Of New Blood Vessels Reduces Heart Disease Plaque In Mice

that require blood vessels in order to grow. These agents are also being investigated in studies of humans who have a type of sight-robbing macular degeneration associated with the proliferation of abnormal new blood vessels in the eye.

While angiogenesis inhibitors are being used in cancer and vision research studies, heart disease investigations are focusing on angiogenesis promoters. In the heart research, scientists are testing in humans certain genes and their protein products that promote angiogenesis. The goal of this research is to circumvent coronary arteries obstructed by the plaque deposits that characterize atherosclerosis, the disease process that causes heart disease.

Very tiny blood vessels called capillaries can grow from the artery wall and invade plaque. Whether these vessels promote plaque growth is uncertain. The Circulation paper provides the "most persuasive evidence to date" that these new blood vessels are a prerequisite for plaque expansion, says Jeffrey M. Isner, M.D., in an editorial accompanying the paper. Isner is chief of vascular medicine and cardiovascular research, department of medicine, St. Elizabeth's Medical Center, Boston, and professor of medicine and pathology, Tufts Medical School, Boston.

Does this evidence suggest that gene and protein treatments designed to promote angiogenesis in people with heart disease could result in the development of larger plaque in these individuals?

Recent human and animal studies on angiogenesis and heart disease have not revealed plaque growth as a result of these treatments, says Isner, one of several scientists conducting this type of research.

The mice in this experiment were fed a "Western diet," which is designed to mimic the cholesterol content of the typical diet eaten in the United States. The amount of plaque the mice developed was measured in the aorta, the large artery that carries blood from the heart to the rest of
'"/>

Contact: Carole Bullock
caroleb@heart.org
214-706-1279
American Heart Association
5-Apr-1999


Page: 1 2 3 4

Related medicine news :

1. Growth hormone treatment improves symptoms of metabolic disorder in postmenopausal women
2. Growth factor grows stem cells that help heal hearts
3. Growth hormone, sex steroid combination not ready for prime time
4. New Technique Induces Growth Across Spinal Cord Injury
5. Growth-Hormone Deficient Babies Are Normal Length At Birth, UB Study Finds
6. New Chemicals Could Lead To First Bone Growth Pill
7. Novel Biological Interaction Found To Explain Blood Vessel Growth To Tumors
8. Common Dental Bleaching Ingredient May Promote Growth Of Precancerous Oral Lesions, UB Dental Researchers Find
9. Clinical Trial Demonstrates Experimental Growth Factor Increases Eligibility For Autologous Stem Cell Transplantation
10. National Jewish Pediatric Asthma Specialist Urges Monitoring Growth When Using Nebulized Glucocorticoids As An Asthma Treatment In Children
11. Health Workers May Experience Costly Dislocation As Health Spending Growth Slows

Post Your Comments:
(Date:3/3/2015)... (PRWEB) March 03, 2015 US Air ... efficiency air purification systems, is pleased to announce that all ... brief supply interruption related to the west coast port strikes. ... just around the corner. , The port ... expected to slow fourth quarter economic growth by as much ...
(Date:3/3/2015)... While it is clear that the prospect of reduced ... are signing up to UBI policies, more mature audiences ... Due to current regulations, the application of UBI in ... full capability is starting to be realised in the ... services are at the top of the value-added services ...
(Date:3/3/2015)... Daylight Savings Time may lead to your ... tips for parents. , Parents and their children may feel ... when they set their clocks forward one hour for Daylight ... -- one hour earlier -- you will have already lost ... thinking about “sleep hygiene” for their kids and teens this ...
(Date:3/3/2015)... Houston, TX (PRWEB) March 03, 2015 ... sponsored by the National Sleep Foundation. The event brings ... the world over. , According to the ... ongoing sleep problems of one form or another. Too ... a greater risk of physical illness and depression, and ...
(Date:3/3/2015)... Topical BioMedics, Inc., announces its March Pain Management ... Tuesday, March 10th, 12pm – 1pm and 4pm to 5pm. ... , The Pain Management Workshops are free ... 10th workshop is “Opioid Addiction: An Over-Medicated Society.” ... 5% of the world’s population, yet consumers 99% of the ...
Breaking Medicine News(10 mins):Health News:Rabbit Air Purifiers Back In Stock at US Air Purifiers LLC 2Health News:Rabbit Air Purifiers Back In Stock at US Air Purifiers LLC 3Health News:TU-Automotive: Wawanesa Insurance to Discuss How UBI Can Produce Happy, Loyal Customers 2Health News:Don’t Let Daylight Savings Disrupt Your Child’s Sleep 2Health News:Medicationdiscountcard.com recognizes sleep awareness week with discounts on sleep meds including Ambien, Lunesta, and Sonata 2Health News:Medicationdiscountcard.com recognizes sleep awareness week with discounts on sleep meds including Ambien, Lunesta, and Sonata 3Health News:Topical BioMedics Hosts March Pain Management Webinar 2Health News:Topical BioMedics Hosts March Pain Management Webinar 3Health News:Topical BioMedics Hosts March Pain Management Webinar 4Health News:Topical BioMedics Hosts March Pain Management Webinar 5
(Date:3/3/2015)... and Markets ( http://www.researchandmarkets.com/research/tbjpmj/blister_packaging ) has announced ... the US 2015-2019" report to their offering. ... to grow at a CAGR of 6.11% over the ... high-visibility packaging that uses pre-formed plastic packs for small ... layer, made either of plastic or aluminum, with cavities ...
(Date:3/3/2015)... , March 3, 2015 Dr. Cummins ... greatest leaders in aesthetics. In addition to ... Plastic and Hand Surgery practice, Dr. Cummins now offers ... Tattoo Removal clinic . Dr. Cummins performs all treatments ... "I founded Louisville Tattoo Removal in order to help ...
(Date:3/3/2015)...  This industry report package offers the most up-to-date market data on ... the world and in the top 10 global countries. Along with a ... following countries: Australia , China ... Italy , Japan , ... , United States The reports ...
Breaking Medicine Technology:United States Blister Packaging Market 2015-2019 - Growing Demand in Pharmaceuticals Industry with Amcor, Bemis, MeadWestvaco & Sonoco Products Dominating 2Surgeon Owned And Operated Louisville Tattoo Removal Offers Astanza Duality Laser Treatments 2Global Safety Glass Market to 2019 - Market Size, Top 10 Countries, Trends, and Forecasts 2
Cached News: