HOME >> MEDICINE >> NEWS
Insight into how the body tells time

St. Louis, June 24, 2002 You may feel different at the dreary hour of 4 a.m. than you do mid-afternoon at 4 p.m. Now, researchers might understand why. A study from Washington University School of Medicine in St. Louis helps explain how genes dictate our biological clock.

Nearly all living things have a natural rhythm that influences their behavior and physiology. This rhythm typically is "circadian", following a near 24-hour cycle. Driven by an internal clock, a creature's natural rhythm is synchronized to the outside world by external cues, like the sun. So far, the products of eight different genes have been discovered to be essential to the operations of this clock. Scientists believe that these genes, in turn, somehow influence the expression of other genes throughout the body in order to control the timing of behaviors like sleep and wakefulness.

Researchers from three laboratories at the School of Medicine, in collaboration with a team at Affymetrix, have identified 22 genes that appear to be rhythmically regulated by the internal clock of the Drosophila fly and found hundreds more genes that are regulated by both light and the internal clock. The study appears in the June 24 issue of the Proceedings of the National Academy of Sciences.

"Understanding how our internal environment responds to our innate biological clock could help us develop better ways of adjusting to challenging circumstances, like unusual work shifts or jet lag following a long journey," says lead investigator Paul H. Taghert, Ph.D., professor of anatomy and neurobiology.

The fruit fly Drosophila melanogaster is one of the most commonly studied organisms, particularly in the pursuit of understanding biological clocks. In the past, researchers only could estimate the number of genes affected by the eight clock genes. But now that the fly's genome has been fully sequenced, scientists can scrutinize nearly all of the animal's 14,000 genes.

The Washing
'"/>

Contact: Gila Z. Reckess
reckessg@msnotes.wustl.edu
314-286-0109
Washington University School of Medicine
24-Jun-2002


Page: 1 2 3

Related medicine news :

1. Insights from intravascular ultrasound explore treatment benefits
2. Novel Imaging Agent Developed By Penn Researchers Provides Insight Into Brains Message Delivery System
3. Researchers Gain Insights Into Drugs Used For Manic-Depression

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/2/2018)... ... August 02, 2018 , ... Mindray, ... 7 Ultrasound system with unique new upgrades at the Society of Vascular Ultrasound ... ZONE Sonography® Technology (ZST), the upgrades include a unique arterial stiffness measurement, which ...
(Date:8/2/2018)... ... August 02, 2018 , ... A new ... topics in acute pain management. In The Role of Acute Care in the ... Engagement Network—an innovative approach to the opioid epidemic launched in the state of ...
(Date:8/2/2018)... ... August 01, 2018 , ... Continuing their momentum in 2018 Sempulse has ... and Chief Investment Officer of Ecliptic Capital, Mike W. Erwin, an early investor in ... have lived in Austin for over 30 years starting companies and investing locally. The ...
(Date:8/2/2018)... MORRISTOWN, N.J. (PRWEB) , ... ... ... Wittig, MD, Orthopedic Oncologist and Sarcoma Surgeon, has been appointed Chairman of ... Orthopedic Oncology at Atlantic Health System, commencing August 1, 2018. ...
(Date:8/1/2018)... and LOS ANGELES (PRWEB) , ... August 01, 2018 , ... ... (MMA) Athlete and two-time UFC Bantamweight Champion TJ Dillashaw have forged a partnership. ... is on the FORBES Top 10 List of CBD Hemp Brands in the country, ...
Breaking Medicine News(10 mins):
(Date:8/9/2018)... ... 2018 , ... Cannabidiol, or CBD, has grabbed national headlines in recent months ... precisely why National Day Calendar collaborated with cbdMD to create a holiday in support ... of National CBD Day after weeks of tireless planning in an effort to bring ...
(Date:8/7/2018)... , ... August 06, 2018 , ... ... gum disease in Clinton, MS using laser dentistry techniques. Using their BIOLASE ... cutting-edge laser gum therapy called REPAIR Perio™. , Affecting the lives of millions ...
(Date:8/7/2018)... ... August 07, 2018 , ... Braun Ambulances is honored to announce ... Bailey Hutchison Convention Center in Dallas, Texas. Braun Ambulances will have four units on ... model. , Fire Rescue International (FRI) is the International Association of Fire Chiefs’ ...
Breaking Medicine Technology:
Cached News: