HOME >> MEDICINE >> NEWS
Interferons for treatment of SARS?

Authors of a research letter in this week's issue of THE LANCET suggest that recombinant interferons - synthetic versions of naturally occurring compounds of the immune system - could be a an effective treatment for Severe Acute Respiratory Syndrome (SARS).

Although antivirals are probably essential for the treatment of SARS-CoV infection, the antiviral ribavirin (a conventional treatment for SARS) is not always effective. Jindrich Cinatl from Frankfurt University Medical School, Germany, and colleagues assessed the antiviral potential of recombinant interferons against two strains of the SARS coronavirus (SARS-CoV) analysed in Frankfurt and Hong Kong. The investigators replicated the virus in two cell lines in a laboratory setting.

Interferon beta was effective in the two cell lines; interferon alpha effectively inhibited SARS-CoV replication, but with a sensitivity index 50-90 times lower than that for interferon beta. Interferon gamma was slightly better than interferon alpha in one of the cell lines, but was completely ineffective in the other cell line.

Jindrich Cinatl comments: "We showed that interferons inhibit SARS-CoV replication in vitro. Interferon beta was most potent, showing prophylactic protection and antiviral potential after infection. Interferon beta could be the drug of choice, alone or in combination with other antiviral drugs, in the treatment of SARS."


'"/>

Contact: Joe Santangelo
j.santangelo@elsevier.com
212-633-3810
Lancet
24-Jul-2003


Page: 1

Related medicine news :

1. Hormonal treatment improves survival in high-risk prostate cancer patients
2. Chronic pain treatments more effective when taken together, new study shows
3. Brain activity prior to treatment flags vulnerability to antidepressant side effects
4. Cultural and social factors influence prostate cancer treatment
5. Research offers hope of new treatments for liver damage
6. First mouse model for multiple system atrophy points to new treatment targets for brain diseases
7. Stanford patient is first to test new treatment for peripheral arterial disease
8. Scientist works on innovative treatments for brain tumors
9. Blacks less likely to get expensive, newer heart treatments
10. Growth hormone treatment improves symptoms of metabolic disorder in postmenopausal women
11. Study examines lessons learned at Africas first public antiretroviral treatment clinic

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/23/2017)... , ... June 23, 2017 , ... Everybody has their ... while others prefer to read it, and some people don't like it at all. ... Here's what they found: , Erotic literature can give readers a taste of their ...
(Date:6/23/2017)... ... June 23, 2017 , ... 21 Middle East and South Asia Leaders Selected ... from government, business and civil society in 11 countries across the Middle East and ... in a transformative exchange of knowledge and ideas with the leading minds in their ...
(Date:6/23/2017)... ... 23, 2017 , ... Ulster University, Magee Campus in Northern Ireland is hosting ... pm to present to graduate students exciting new and innovative hope research based on ... by The Health Improvement Service of the Western Health & Social Care Trust (WHSCT) ...
(Date:6/23/2017)... ... June 23, 2017 , ... Moore Insurance, ... area with access to asset protection and financial planning services, is teaming up ... improving the lives of children with cancer and other chronic diseases. , The ...
(Date:6/22/2017)... ... June 22, 2017 , ... ... from the American Heart Association (AHA) to launch a Rheumatic Heart Disease Center, ... prevention and diagnosis of rheumatic heart disease (RHD) in high-risk, financially disadvantaged countries ...
Breaking Medicine News(10 mins):
(Date:6/16/2017)... , June 16, 2017  Exactly 50 years ago ... off what later became known as the San Francisco "Summer ... ) is unveiling two radical innovations in strategic market research ... This announcement marks the beginning of Northern Light,s "Summer of ... ...
(Date:6/12/2017)... , June 12, 2017 Kineta, Inc., a biotechnology ... Kineta Vice President of R&D and Head of ... Pandemic Preparedness for the Northwest and Beyond meeting ... on June 14, 2017 from 8:30-10:30 AM PDT at the ... Dr. Bedard will be joined by other ...
(Date:6/8/2017)... MAITLAND, Fla. , June 8, 2017  Less ... ransomware attack that hit more than 200,000 companies, including hospital ... is being heralded as one of the largest online ... technology in the healthcare market, it is imperative that ... can protect their data from this — and many ...
Breaking Medicine Technology:
Cached News: