HOME >> MEDICINE >> NEWS
International Study Raises Hopes For Heart Transplant Patients

Preliminary six month findings of a Multicenter International Study of the organ rejection drug, Neoral, may offer significant benefits to heart transplant recipients. Clinical results obtained from 24 research centers in five countries were reported today at the International Society For Heart and Lung Transplantation Meeting in Chicago, Illinois.

According to Howard J. Eisen, M.D., Medical Director of the Heart Transplantation Unit at Temple University Hospital, "heart transplant patients receiving Neoral experienced significantly fewer infections and a reduced number of rejections requiring antibody therapy." This two-year, double blind International Study compares the safety and effectiveness of conventional Cyclosporine A (Sandimmune) with Neoral in 380 heart transplant recipients. All patients received either Sandimmune or Neoral as part of a triple immunosuppressive regimen including steroids and azathioprine.

"Since fewer Neoral-treated patients required supplemental steroids and antibody therapy, there were also fewer infections in these heart transplant recipients," says Dr. Eisen.

In addition, lower dosages of this immunosuppressive agent were needed during the initial four weeks after treatment to achieve therapeutic blood levels. Neoral is a new formulation of Cyclosporine designed to provide increased and more reliable absorption of the medication. These findings suggest that Neoral has clinical advantages, which may translate into improved outcomes for heart transplant recipients.

In 1995, the U.S. Food and Drug Administration approved Neoral for the prevention of organ rejection. Based upon scientific registry data from the United Network for Organ Sharing (UNOS), there are currently about 3,945 patients waiting for a heart transplant. "Due to the shortage of organ donors, we need to develop new treatments to prevent organ rejection in heart transplant patients," indicates Dr. Eisen.
'"/>

Contact: Joseph J. DiBartolomeo, Ph.D.
DiBartoJ@mail.Temple.edu
215-707-4598
Temple University Health System
18-Apr-1998


Page: 1 2

Related medicine news :

1. International breast cancer prevention study launches in the United States and Canada
2. National Academies advisory: May 2 Symposium on International Science Policy
3. Awards & fellowships at the International & American Association for Dental Research General Session
4. Lectures, keynoters, symposia highlight International Dental Research meeting
5. Advances in Uterine Leiomyoma Research: 2nd NIH International Congress
6. International gathering of experts to share retinoblastoma breakthroughs
7. International trial of two microbicides begins
8. International gathering at UH examines top computer code
9. International trial finds benefits of breast MRI in women at high risk
10. International study provides culture-by-culture clues to family violence and abuse
11. St. Jude scientist wins International Society of Experimental Hematology award

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/11/2019)... ... , ... Inland Detox, Inc. has just moved to a new location in ... the Temecula Valley and it’s the perfect place for long-term residential alcohol and ... as well as double occupancy rooms, a 2nd home where all treatment takes place, ...
(Date:10/10/2019)... , ... October 10, 2019 , ... ... Annual Conference, Nutrition 21 was excited to hear the significant results of an ... blood flow impact of Nitrosigine®. The clinical study poster entitled “The Acute Effects ...
(Date:10/8/2019)... (PRWEB) , ... October 08, 2019 , ... Dr. Amir ... disease in San Jose, CA experience relief from this common and treatable condition. Dr. ... order to save adults from living with uncomfortable symptoms, including tender and bleeding gums, ...
(Date:10/8/2019)... ... October 08, 2019 , ... Over the past three decades, Buffalo Wings & ... sports restaurant category by providing a higher-quality product and experience than the competition. Now, ... as a "RAISE A MUG FOR THE CAUSE" campaign in support of Breast Cancer ...
(Date:10/8/2019)... Mass. (PRWEB) , ... October 08, 2019 , ... ... MCN Healthcare to seamlessly integrate skills and procedures content from ... designed to help nurses and allied health professionals master critical skills. MCN provides ...
Breaking Medicine News(10 mins):
(Date:10/15/2019)... Ala. (PRWEB) , ... October 14, 2019 , ... An ... in a wrongful death medical malpractice case that breaks records for Lee County. , ... pains, difficulty breathing, and cough. She had been there just two days earlier with ...
(Date:10/11/2019)... , ... October 11, 2019 , ... ... starting October 13, 2019, to recognize the dedication, compassion and quality patient outcomes ... collaborative process, providing a unique and vital link between patients, providers and payers ...
(Date:10/10/2019)... ... October 10, 2019 , ... Global Composer ... ITTF Parkinson World Table Tennis Championships, October 11th – 13th,  , The debilitating effects ... public. So, he sought to find a way to combat the disease. A ...
Breaking Medicine Technology:
Cached News: