HOME >> MEDICINE >> NEWS
International Study Raises Hopes For Heart Transplant Patients

Preliminary six month findings of a Multicenter International Study of the organ rejection drug, Neoral, may offer significant benefits to heart transplant recipients. Clinical results obtained from 24 research centers in five countries were reported today at the International Society For Heart and Lung Transplantation Meeting in Chicago, Illinois.

According to Howard J. Eisen, M.D., Medical Director of the Heart Transplantation Unit at Temple University Hospital, "heart transplant patients receiving Neoral experienced significantly fewer infections and a reduced number of rejections requiring antibody therapy." This two-year, double blind International Study compares the safety and effectiveness of conventional Cyclosporine A (Sandimmune) with Neoral in 380 heart transplant recipients. All patients received either Sandimmune or Neoral as part of a triple immunosuppressive regimen including steroids and azathioprine.

"Since fewer Neoral-treated patients required supplemental steroids and antibody therapy, there were also fewer infections in these heart transplant recipients," says Dr. Eisen.

In addition, lower dosages of this immunosuppressive agent were needed during the initial four weeks after treatment to achieve therapeutic blood levels. Neoral is a new formulation of Cyclosporine designed to provide increased and more reliable absorption of the medication. These findings suggest that Neoral has clinical advantages, which may translate into improved outcomes for heart transplant recipients.

In 1995, the U.S. Food and Drug Administration approved Neoral for the prevention of organ rejection. Based upon scientific registry data from the United Network for Organ Sharing (UNOS), there are currently about 3,945 patients waiting for a heart transplant. "Due to the shortage of organ donors, we need to develop new treatments to prevent organ rejection in heart transplant patients," indicates Dr. Eisen.
'"/>

Contact: Joseph J. DiBartolomeo, Ph.D.
DiBartoJ@mail.Temple.edu
215-707-4598
Temple University Health System
18-Apr-1998


Page: 1 2

Related medicine news :

1. International breast cancer prevention study launches in the United States and Canada
2. National Academies advisory: May 2 Symposium on International Science Policy
3. Awards & fellowships at the International & American Association for Dental Research General Session
4. Lectures, keynoters, symposia highlight International Dental Research meeting
5. Advances in Uterine Leiomyoma Research: 2nd NIH International Congress
6. International gathering of experts to share retinoblastoma breakthroughs
7. International trial of two microbicides begins
8. International gathering at UH examines top computer code
9. International trial finds benefits of breast MRI in women at high risk
10. International study provides culture-by-culture clues to family violence and abuse
11. St. Jude scientist wins International Society of Experimental Hematology award

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/16/2019)... ... June 14, 2019 , ... ... Security solutions, today announced it has received the coveted “2019 Best DLP Solution ... that Works Platform along with the latest additions to its Data Security Portfolio ...
(Date:6/14/2019)... , ... June 14, 2019 , ... ... Tempur-Pedic® Mattress & Pink Bag Event® scheduled for Saturday, July 13th. UBCF is ... men and children directly impacted by breast cancer. This second event was added ...
(Date:6/13/2019)... ... June 13, 2019 , ... MMJ BioPharma Cultivation, a premier ... memorandum of understanding (MOU) with MMJ International Holdings to grow cannabis and supply ... BioPharma Cultivation will be supplying MMJIH with extracts from the marijuana plant to ...
(Date:6/13/2019)... ... June 13, 2019 , ... Pure Ratios, the ... cannabis delivery company, Driven Deliveries, Inc., the only publicly traded cannabis delivery service ... the population of California with overnight cannabis delivery to major thriving markets such ...
(Date:6/13/2019)... ... June 13, 2019 , ... ... everyone in healthcare, today announced that Jon Elwell, the company’s CEO, has been ... DirectTrust is a non-profit health care industry alliance created to support ...
Breaking Medicine News(10 mins):
(Date:6/13/2019)... ... June 13, 2019 , ... Homecare Homebase ... the new Smart Scheduling product, part of the HCHB Intelligence Suite, at the ... uses complex algorithms to create highly efficient routing, mapping and scheduling for home ...
(Date:6/13/2019)... ... 13, 2019 , ... Access Healthcare , a leading provider of healthcare ... at the HFMA Annual Conference 2019 which will be held on June ... Access Healthcare, says, “HFMA Annual Conference has inspired us in many ways – right ...
(Date:6/13/2019)... ... , ... RxNT announced today that it has been named by ... RxNT is a leader in healthcare technology solutions. This is the fourth time RxNT ... highlight the best software products from North American small businesses. RxNT won the FrontRunner ...
Breaking Medicine Technology:
Cached News: