HOME >> MEDICINE >> NEWS
International trial of two microbicides begins

A large, multisite trial designed to examine the safety and preliminary effectiveness of two candidate topical microbicides to prevent HIV infection has opened to volunteer enrollment. The trial, sponsored by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, represents a partnership among various research institutions in Africa and the United States.

Although no licensed microbicides are available to the public currently, scientists hope these agents--designed to be applied to the surface of the vagina to prevent sexually transmitted infections (STIs)--will one day be a key tool in the fight against HIV/AIDS.

Women make up nearly half of all people living with HIV worldwide. "The majority of new cases of HIV infection in women result from heterosexual intercourse, but women may not always be able to insist that their male partners use measures to prevent HIV transmission," notes NIAID Director Anthony S. Fauci, M.D. "If effective, microbicides would be a valuable woman-controlled means of slowing the pace of the HIV/AIDS epidemic," Dr. Fauci adds.

The first volunteers were enrolled this week at sites in Durban, South Africa, and at the University of Pennsylvania in Philadelphia. Enrollment will begin shortly at sites in four additional African countries--Malawi, Tanzania, Zimbabwe and Zambia. Approximately 3,220 women will be enrolled in the trial, which is expected to last approximately 30 months.

"This is the first microbicide safety and effectiveness trial of this magnitude to be conducted by NIAID," says Roberta J. Black, Ph.D., Topical Microbicide Team Leader in NIAID's Division of AIDS. "It is a critical trial evaluating two topical microbicides with differing mechanisms of action," she adds.

The microbicides to be tested are PRO 2000 and BufferGel. Produced by Indevus Pharmaceuticals, Lexington, MA, PRO 2000 has shown activity against HIV and other STIs in bot
'"/>

Contact: Anne A. Oplinger
aoplinger@niaid.nih.gov
301-402-1663
NIH/National Institute of Allergy and Infectious Diseases
11-Feb-2005


Page: 1 2

Related medicine news :

1. International breast cancer prevention study launches in the United States and Canada
2. National Academies advisory: May 2 Symposium on International Science Policy
3. Awards & fellowships at the International & American Association for Dental Research General Session
4. Lectures, keynoters, symposia highlight International Dental Research meeting
5. Advances in Uterine Leiomyoma Research: 2nd NIH International Congress
6. International gathering of experts to share retinoblastoma breakthroughs
7. International gathering at UH examines top computer code
8. International trial finds benefits of breast MRI in women at high risk
9. International study provides culture-by-culture clues to family violence and abuse
10. St. Jude scientist wins International Society of Experimental Hematology award
11. International MRC trial finds a routine treatment for head injury may do more harm than good

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/22/2019)... ANGELES (PRWEB) , ... May 22, 2019 , ... The ... Marie Dubois. The fashion expert and creator shares seven ways for women to step ... fashion, The Power of Color combines spirituality, music, and dancing to further self-expression. Women ...
(Date:5/22/2019)... ... 22, 2019 , ... For over 33 years, NJ Top Dentists Dr. Michael ... their Bernardsville, Chester, Hackettstown, and Bloomfield locations. With four locations, these NJ Top Dentists ... “Orthodontics is about a change for the better, no matter what your age,” says ...
(Date:5/21/2019)... ... , ... AltMed Florida has announced its first Orlando area MÜV™ Medical Cannabis Dispensary ... at exit 94) at 10 a.m. Friday, May 24, pending final approvals. , Just north ... Apopka, Sanford and many others along the busy I-4 corridor. , This is only ...
(Date:5/21/2019)... ... May 21, 2019 , ... Dr. Mauricio Martinez and ... untreated obstructive sleep apnea as well as common symptoms to look out for including ... who have been diagnosed with sleep apnea and treats the condition with guided lifestyle ...
(Date:5/21/2019)... ... May 21, 2019 , ... ... in partnership with BEYOND, an authorized HITRUST CSF Assessor organization, today introduced their ... Certification. By providing a library of hundreds of inheritable controls, MagicBox is designed ...
Breaking Medicine News(10 mins):
(Date:5/22/2019)... ... May 22, 2019 , ... Ziegler, a specialty ... the successful closing of the $22,375,000 Series 2019 for Trevecca Nazarene University. The ... of the Metropolitan Government of Nashville and Davidson County, Tennessee. Proceeds from the ...
(Date:5/22/2019)... ... May 22, 2019 , ... Southern Illinois University Edwardsville’s Mark Luer, PharmD, FCCP, ... served as interim dean since July 2018. The appointment is subject to SIU Board ... of accomplishment during Dr. Luer’s service as interim dean, and we are excited to ...
(Date:5/22/2019)... ... 22, 2019 , ... CBDNhance, a new player in the ... are designed to increase the benefits of CBD, especially for people seeking pain ... and other natural ingredients that have been shown to help with CBD absorption ...
Breaking Medicine Technology:
Cached News: