HOME >> MEDICINE >> NEWS
International trial of two microbicides begins

A large, multisite trial designed to examine the safety and preliminary effectiveness of two candidate topical microbicides to prevent HIV infection has opened to volunteer enrollment. The trial, sponsored by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, represents a partnership among various research institutions in Africa and the United States.

Although no licensed microbicides are available to the public currently, scientists hope these agents--designed to be applied to the surface of the vagina to prevent sexually transmitted infections (STIs)--will one day be a key tool in the fight against HIV/AIDS.

Women make up nearly half of all people living with HIV worldwide. "The majority of new cases of HIV infection in women result from heterosexual intercourse, but women may not always be able to insist that their male partners use measures to prevent HIV transmission," notes NIAID Director Anthony S. Fauci, M.D. "If effective, microbicides would be a valuable woman-controlled means of slowing the pace of the HIV/AIDS epidemic," Dr. Fauci adds.

The first volunteers were enrolled this week at sites in Durban, South Africa, and at the University of Pennsylvania in Philadelphia. Enrollment will begin shortly at sites in four additional African countries--Malawi, Tanzania, Zimbabwe and Zambia. Approximately 3,220 women will be enrolled in the trial, which is expected to last approximately 30 months.

"This is the first microbicide safety and effectiveness trial of this magnitude to be conducted by NIAID," says Roberta J. Black, Ph.D., Topical Microbicide Team Leader in NIAID's Division of AIDS. "It is a critical trial evaluating two topical microbicides with differing mechanisms of action," she adds.

The microbicides to be tested are PRO 2000 and BufferGel. Produced by Indevus Pharmaceuticals, Lexington, MA, PRO 2000 has shown activity against HIV and other STIs in bot
'"/>

Contact: Anne A. Oplinger
aoplinger@niaid.nih.gov
301-402-1663
NIH/National Institute of Allergy and Infectious Diseases
11-Feb-2005


Page: 1 2

Related medicine news :

1. International breast cancer prevention study launches in the United States and Canada
2. National Academies advisory: May 2 Symposium on International Science Policy
3. Awards & fellowships at the International & American Association for Dental Research General Session
4. Lectures, keynoters, symposia highlight International Dental Research meeting
5. Advances in Uterine Leiomyoma Research: 2nd NIH International Congress
6. International gathering of experts to share retinoblastoma breakthroughs
7. International gathering at UH examines top computer code
8. International trial finds benefits of breast MRI in women at high risk
9. International study provides culture-by-culture clues to family violence and abuse
10. St. Jude scientist wins International Society of Experimental Hematology award
11. International MRC trial finds a routine treatment for head injury may do more harm than good

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:9/3/2020)... (PRWEB) , ... September 03, 2020 , ... ... Spa Show 2021 will be held Wednesday, April 7, to Saturday, April 10, ... January. , Medical Spa Show is a national trade show for non-invasive medical ...
(Date:9/2/2020)... ... 02, 2020 , ... RAM Technologies, Inc., the perennial leader ... Special Needs plans, is proud to support the 2020 National Conferences on Medicare, ... supporting the event as a sponsor and exhibitor and will be showcasing their ...
(Date:9/1/2020)... ... September 01, 2020 , ... Feeding Matters , the first organization in ... Disorder (PFD), is pleased to announce that the U.S. Centers for Disease Control and ... in the next edition of the U.S. International Classification of Diseases (ICD ) ...
(Date:8/31/2020)... ... August 31, 2020 , ... Cardiothoracic surgeons at Allegheny General ... Carnegie Mellon University (CMU) to develop a new heart monitoring device designed to ... surgery. , The AGH/CMU team was recently awarded a “Trailblazer” grant from the ...
(Date:8/31/2020)... Miss. (PRWEB) , ... August 31, 2020 , ... ... (GCPP) recently donated 1,400 N95 face masks to medical first responders across the ... continued to make donations of personal protective equipment (PPE) medical centers , ...
Breaking Medicine News(10 mins):
(Date:9/1/2020)... ... 01, 2020 , ... September is National Ovarian Cancer Awareness Month. Ovarian ... other cancer of the female reproductive system. The American Cancer Society estimates that ... women will die from this disease. Throughout the month of September, Women’s Excellence ...
(Date:8/31/2020)... (PRWEB) , ... August 31, 2020 , ... ... research and advisory guide, has named Cloudticity a Gold winner in the 15th ... industry and peer recogniti o ns from Network Products Guide honoring ...
(Date:8/27/2020)... Pa. (PRWEB) , ... August 27, 2020 , ... ... care coordination software, today announced the successful completion of their 2020 System and ... well as their HITRUST® interim assessment and MARS-E compliance assessment. These achievements reflect ...
Breaking Medicine Technology:
Cached News: