HOME >> MEDICINE >> NEWS
International trial of two microbicides begins

A large, multisite trial designed to examine the safety and preliminary effectiveness of two candidate topical microbicides to prevent HIV infection has opened to volunteer enrollment. The trial, sponsored by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, represents a partnership among various research institutions in Africa and the United States.

Although no licensed microbicides are available to the public currently, scientists hope these agents--designed to be applied to the surface of the vagina to prevent sexually transmitted infections (STIs)--will one day be a key tool in the fight against HIV/AIDS.

Women make up nearly half of all people living with HIV worldwide. "The majority of new cases of HIV infection in women result from heterosexual intercourse, but women may not always be able to insist that their male partners use measures to prevent HIV transmission," notes NIAID Director Anthony S. Fauci, M.D. "If effective, microbicides would be a valuable woman-controlled means of slowing the pace of the HIV/AIDS epidemic," Dr. Fauci adds.

The first volunteers were enrolled this week at sites in Durban, South Africa, and at the University of Pennsylvania in Philadelphia. Enrollment will begin shortly at sites in four additional African countries--Malawi, Tanzania, Zimbabwe and Zambia. Approximately 3,220 women will be enrolled in the trial, which is expected to last approximately 30 months.

"This is the first microbicide safety and effectiveness trial of this magnitude to be conducted by NIAID," says Roberta J. Black, Ph.D., Topical Microbicide Team Leader in NIAID's Division of AIDS. "It is a critical trial evaluating two topical microbicides with differing mechanisms of action," she adds.

The microbicides to be tested are PRO 2000 and BufferGel. Produced by Indevus Pharmaceuticals, Lexington, MA, PRO 2000 has shown activity against HIV and other STIs in bot
'"/>

Contact: Anne A. Oplinger
aoplinger@niaid.nih.gov
301-402-1663
NIH/National Institute of Allergy and Infectious Diseases
11-Feb-2005


Page: 1 2

Related medicine news :

1. International breast cancer prevention study launches in the United States and Canada
2. National Academies advisory: May 2 Symposium on International Science Policy
3. Awards & fellowships at the International & American Association for Dental Research General Session
4. Lectures, keynoters, symposia highlight International Dental Research meeting
5. Advances in Uterine Leiomyoma Research: 2nd NIH International Congress
6. International gathering of experts to share retinoblastoma breakthroughs
7. International gathering at UH examines top computer code
8. International trial finds benefits of breast MRI in women at high risk
9. International study provides culture-by-culture clues to family violence and abuse
10. St. Jude scientist wins International Society of Experimental Hematology award
11. International MRC trial finds a routine treatment for head injury may do more harm than good

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/16/2018)... ... October 16, 2018 , ... Intrinsic ... simple, easy-to-use software for biopharma companies. By pairing the InTime time tracker with ... resourcing questions without spending millions of dollars implementing a complicated enterprise project management ...
(Date:10/16/2018)... (PRWEB) , ... October 16, 2018 , ... The months of training are over. The ... their bodies will probably feel like they were put through the wringer after the big ... sports injuries team at Medicine in Motion on how to treat the body and mind ...
(Date:10/13/2018)... ... October 12, 2018 , ... Convoy of Hope’s Disaster Services Team is currently ... distribution site set up to serve hurricane survivors with water, food, baby products, hygiene ... to 50 additional truckloads of supplies are in motion to Florida. , ...
(Date:10/11/2018)... ... October 11, 2018 , ... HCS Consulting, ... healthcare organizations nationwide, announced today the launch of its new website. This new ... of services while offering a more comprehensive understanding of the Company’s value proposition ...
(Date:10/6/2018)... (PRWEB) , ... October 06, 2018 , ... ... standards for healthcare treatment professionals who treat the full spectrum of eating disorders ... the organization’s Presidents Council. , “As with each of our Presidents Council members, ...
Breaking Medicine News(10 mins):
(Date:10/11/2018)... ... 11, 2018 , ... Alice* is artistic, intelligent and on her third school placement. Her parents ... kick off the bed covers, often waking up in a pool of sweat with terrifying ... would worry about everything, howled when she was separated from her parents and often demanded ...
(Date:10/11/2018)... ... October 11, 2018 , ... Sun Nuclear Corporation announced today ... as a reference site for its SunCHECK™ Quality Management Platform . The Centre ... used for radiation therapy Quality Management on almost 1,500 linear accelerators at nearly 500 ...
(Date:10/7/2018)... ... , ... No one likes to think about an emergency, even what might seem like small ... The local ServPro professional, a trusted leader in the restoration industry, has a list of ... No time is a good time for an emergency, but having a few things in ...
Breaking Medicine Technology:
Cached News: