HOME >> MEDICINE >> NEWS
International trial of two microbicides begins

A large, multisite trial designed to examine the safety and preliminary effectiveness of two candidate topical microbicides to prevent HIV infection has opened to volunteer enrollment. The trial, sponsored by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, represents a partnership among various research institutions in Africa and the United States.

Although no licensed microbicides are available to the public currently, scientists hope these agents--designed to be applied to the surface of the vagina to prevent sexually transmitted infections (STIs)--will one day be a key tool in the fight against HIV/AIDS.

Women make up nearly half of all people living with HIV worldwide. "The majority of new cases of HIV infection in women result from heterosexual intercourse, but women may not always be able to insist that their male partners use measures to prevent HIV transmission," notes NIAID Director Anthony S. Fauci, M.D. "If effective, microbicides would be a valuable woman-controlled means of slowing the pace of the HIV/AIDS epidemic," Dr. Fauci adds.

The first volunteers were enrolled this week at sites in Durban, South Africa, and at the University of Pennsylvania in Philadelphia. Enrollment will begin shortly at sites in four additional African countries--Malawi, Tanzania, Zimbabwe and Zambia. Approximately 3,220 women will be enrolled in the trial, which is expected to last approximately 30 months.

"This is the first microbicide safety and effectiveness trial of this magnitude to be conducted by NIAID," says Roberta J. Black, Ph.D., Topical Microbicide Team Leader in NIAID's Division of AIDS. "It is a critical trial evaluating two topical microbicides with differing mechanisms of action," she adds.

The microbicides to be tested are PRO 2000 and BufferGel. Produced by Indevus Pharmaceuticals, Lexington, MA, PRO 2000 has shown activity against HIV and other STIs in bot
'"/>

Contact: Anne A. Oplinger
aoplinger@niaid.nih.gov
301-402-1663
NIH/National Institute of Allergy and Infectious Diseases
11-Feb-2005


Page: 1 2

Related medicine news :

1. International breast cancer prevention study launches in the United States and Canada
2. National Academies advisory: May 2 Symposium on International Science Policy
3. Awards & fellowships at the International & American Association for Dental Research General Session
4. Lectures, keynoters, symposia highlight International Dental Research meeting
5. Advances in Uterine Leiomyoma Research: 2nd NIH International Congress
6. International gathering of experts to share retinoblastoma breakthroughs
7. International gathering at UH examines top computer code
8. International trial finds benefits of breast MRI in women at high risk
9. International study provides culture-by-culture clues to family violence and abuse
10. St. Jude scientist wins International Society of Experimental Hematology award
11. International MRC trial finds a routine treatment for head injury may do more harm than good

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:9/9/2019)... ... September 09, 2019 , ... Drs. Steven White, Brad ... now welcome individuals with tooth loss in Davidson, NC who are seeking permanent ... single or multiple missing teeth and want the advantages of dental implants ...
(Date:9/9/2019)... ... September 09, 2019 , ... Cardinal Park Family Dental Care is ... counting. The practice offers family dentistry , laser gum disease treatment, full mouth ... the 20th year that Cardinal Park Family Dental Care has provided state-of-the-art, comprehensive dental ...
(Date:9/9/2019)... N.C. (PRWEB) , ... September 09, 2019 , ... ... voted unanimously to adopt an organization-wide policy focusing on a diabetes-language movement (#LanguageMatters) ... language that is neutral and non-judgmental, free from stigma, respectful and inclusive, empowering, ...
(Date:9/8/2019)... ... September 09, 2019 , ... Stetson University ranks No. 5 on ... South, released today. In addition, Stetson appears on five additional lists in the same ... No. 14; Campus Ethnic Diversity, No. 34; and a new list this year, Top ...
(Date:9/8/2019)... ... September 06, 2019 , ... ... historic milestone as its fall 2019 enrollment has reached an all-time high with ... in master’s and doctoral level candidates, totaling 374 students. The total does not ...
Breaking Medicine News(10 mins):
(Date:9/11/2019)... ... September 12, 2019 , ... Understanding the Drug Supply ... Webinar, Thursday, Sept. 26, 2019, 1:30-3:00 p.m. EDT, https://www.fdanews.com/understanding-the-dscsa , Need ... the company clear on nuances of the guidelines regulating the drug supply chain? ...
(Date:9/11/2019)... ... September 11, 2019 , ... Designs for Health (DFH) – ... Annatto-GG™ 150 , a revolutionary compound that supports healthy aging, specifically muscle protein ... in nature through the annatto plant, it’s a nutrient produced by the body ...
(Date:9/11/2019)... ... September 11, 2019 , ... Abilene Christian University (ACU) is ... Practice (DNP) degree. The online BSN to DNP program pathway is meant to serve ... Science in Nursing (BSN) degree to a Doctor of Nursing Practice degree. , ...
Breaking Medicine Technology:
Cached News: