Intravenous Immunoglobulin Reduces Steroid Insensitivity, Hospitalizations Of,,People With Severe Asthma, According To National Jewish Research

DENVER-People with severe asthma who are "insensitive" to steroids need less of the medication, fewer "bursts" of it in emergencies and spend less time in the hospital when using intravenous immunoglobulin (IVIG) in conjunction with steroids, according to research published today in the Journal of Allergy and Clinical Immunology.

Researchers found that during the 6-month study, patients had fewer hospitalizations for asthma attacks than in the 6 months prior to the study, even though they used less glucocorticoids, known generally as steroids. IVIG also was as effective in people whose asthma can be treated with glucocorticoids, as it was in people whose asthma usually doesn't respond to glucocorticoids, or who are "steroid-insensitive." Researchers believe IVIG increases steroid sensitivity of the lungs to steroids, in part, by reducing lung inflammation.

"We saw patients whose asthma does very poorly and who needed high doses of steroids to control the disease," said Erwin Gelfand, M.D., a pediatric immunology and asthma specialist and chair of the Department of Pediatrics at National Jewish Medical and Research Center.

While steroid-insensitive patients must take higher doses to achieve minimal control of their disease, they also may become dependent on the medication to breathe normally. Researchers found that by taking IVIG in conjunction with glucocorticoids, patients could use less glucocorticoids more efficiently.

Long-term use of glucocorticoids can stunt growth in children or cause osteoporosis, while IVIG has few side effects. "Compared to steroids, IVIG is not toxic at all," Dr. Gelfand said. "In addition, lowering the amount of steroids a patient takes reduces side effects and the patient's quality of life improves dramatically."

IVIG treatments cost several thousand dollars each month for people with severe asthma, but many health insurance companies cover the cost because, as this study shows, IVIG lowers emergency room an

Contact: Jordan Gruener
National Jewish Medical and Research Center

Page: 1 2

Related medicine news :

1. UCSF Study Shows That An Herbal Therapy Reduces PSA Levels By Half In Men With Advanced Prostate Cancer
2. Bone Marrow With Heart And Lung Transplants Reduces Rejection Of Transplanted Organs, Reports University Of Pittsburgh
3. Bone Marrow With Organ Transplants Reduces Rejection Of Transplanted Organs, Reports University Of Pittsburgh
4. AVANT Atherosclerosis Vaccine Raises HDL, Reduces Atherosclerosis In Vaccinated Animals
5. Inhibiting Growth Of New Blood Vessels Reduces Heart Disease Plaque In Mice
6. UCSF Study Shows Drug Reduces Risk Of Spine And Hip Fractures By Half In Women With Osteoporosis
7. Scientists Discover How Aspirin Reduces Inflammation
8. Novel Therapy Significantly Reduces Spinal Fractures In Postmenopausal WomenWith Two Years Of Therapy
9. New Data Show Evista Reduces Spinal Fractures
10. Drug Reduces Heart Attack, Death Rates In Patients With Unstable Angina
11. Lewin Study Confirms Diabetes Treatment Centers of Americas Diabetes NetCareSM Program Improves Health Status, Reduces Medical Costs

Post Your Comments:

(Date:8/28/2020)... ... August 28, 2020 , ... ... set out to continue helping the specialty-diet community connect with great, gluten-free ... products, get coupons, enter giveaways, chat with brands & watch over 50 educational ...
(Date:8/28/2020)... ... August 28, 2020 , ... Ziegler, a ... on its investment in Synchronous Health, a tech-enabled behavioral health and well-being solutions ... of human empathy with artificial intelligence (AI) to increase access and quality of ...
(Date:8/27/2020)... (PRWEB) , ... August 27, 2020 , ... ... has joined the Walk-in Dermatology team in its Greenvale, New York location. ... Nail and Skin Care Institute. She is certified in chemical peels, microdermabrasion, Hydrafacial ...
(Date:8/27/2020)... ... August 27, 2020 , ... Evolution Labs announced today ... their students with Suite360:Mental Health and Prevention, a program developed to help students ... Trafficking Prevention. , Florida schools and districts must provide their students with preventative ...
(Date:8/26/2020)... ... August 26, 2020 , ... Harmony Healthcare IT, ... Best in KLAS Software & Services Report as the Category Leader in Data ... wide variety of complex clinical and financial software systems for enterprise-wide inpatient organizations ...
Breaking Medicine News(10 mins):
(Date:9/1/2020)... ... September 01, 2020 , ... While coronavirus cases continue to increase across ... and community organizations remain closed. Because about 80% of blood donations are made at ... blood donors and blood drive hosts to ensure blood products are readily available for ...
(Date:8/31/2020)... YORK (PRWEB) , ... August 31, 2020 , ... If you live in New York ... The real estate part makes sense, it’s the law of supply and demand, but are ... Center has a significant percentage of their patients that make the four-hour trip to ...
(Date:8/28/2020)... ... August 28, 2020 , ... Dr. Mark Surrey has been in ... serves as a clinical professor in the Department of OBGYN at UCLA’s David Geffen ... & Pacific Coast Reproductive Society and is a Clinical Director of Fellowship Training for ...
Breaking Medicine Technology:
Cached News: