Investigational mesh 'jackets' studied as an experimental therapy for heart failure

LOS ANGELES, CA (August 5, 2002) A 73-year-old retired Head Start teacher has become the first patient in the Los Angeles area to be implanted with a first-of-its-kind mesh "jacket" that is positioned around the heart in an effort to slow or reverse damage caused by progressive heart failure. The experimental device was implanted on Monday, July 15, and the patient went home from the hospital a week later.

Physicians at Cedars-Sinai Medical Center report that Evelyn Maiden, a resident of Little Rock, Ca., became the fourth patient in the state to receive the CorCapTM cardiac support device (CSD) developed by Acorn Cardiovascular Inc. Cedars-Sinai is one of 28 centers in the United States and Canada participating in the Acorn study, which has enrolled more than 144 patients nationwide.

"Based on the progress Evelyn is making, we hope that she'll be able to resume her routine activities over the coming weeks," said Kathy E. Magliato, M.D., cardiothoracic surgeon and one of two principal investigators at Cedars-Sinai studying the device.

Because Evelyn was in the advanced stages of heart failure and was not a good candidate for a heart transplant, she had very few options remaining, said Dr. Magliato. "For her and many other patients like her, the experimental Acorn device may help extend and improve quality of life."

Evelyn's device was implanted by Alfredo Trento, M.D., director of the Division of Cardiothoracic Surgery, and Dr. Magliato, director of the division's Cardiac Mechanical Assist Device Program. Steven S. Khan, M.D., cardiologist, director of the Heart Failure Program and director of Clinical Trials in the Division of Cardiology at Cedars-Sinai, is the other principal investigator on the study.

Several conditions including coronary artery disease, long-standing high blood pressure, and leaking heart valves can lead to congestive heart failure. When the heart's pumping ability is impaired for any reaso

Contact: Sandra Van
Cedars-Sinai Medical Center

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