HOME >> MEDICINE >> NEWS
Investigators stop part of drug-taking in Women's Health Initiative

WINSTON-SALEM, N.C. Women on one major study group of the massive Women's Health Initiative -- those who are taking a combination of estrogen plus progestin as hormone replacement therapy -- are being told to stop taking their study drugs.

About 570 women in Winston-Salem and Greensboro are enrolled in that portion of the Women's Health Initiative, according to one of the study's local investigators, Denise E. Bonds, M.D., M.P.H., assistant professor of internal medicine (general) at Wake Forest University Baptist Medical Center.

The study's Data and Safety Monitoring Board found that the risks of taking the combination -- 0.625 milligrams a day of conjugated equine estrogens plus 2.5 milligrams per day of medroxyprogesterone -- now exceed the benefits. "Compared to those taking placebo, more women taking active estrogen plus progestin developed breast cancer or experienced cardiovascular events such as heart attacks, strokes, pulmonary emboli and deep vein thromboses."

The study was testing this estrogen-progestin combination because 7 million women in the United States take this same combination daily. One trade name for it is Prempro.

Both Bonds and the National Heart, Lung and Blood Institute stressed that nothing has changed for other groups in the study, and women taking estrogen alone and women in the dietary, calcium and vitamin D groups and the observational study are asked to participate as before.

Though they are being told to stop taking their study medication of estrogen plus progestin, women in that group will continue to have their regular contacts with the Women's Health Initiative and continue to get regular examinations and mammograms.

The study investigators found some positive benefits from estrogen plus progestin: the women had a lower risk of colorectal cancer and of fractures, especially hip fractures. "But the balance of risks significantly outweighed the benefits," they said.

However, the inve
'"/>

Contact: Robert Conn
rconn@wfubmc.edu
336-716-4587
Wake Forest University Baptist Medical Center
9-Jul-2002


Page: 1 2

Related medicine news :

1. Statement on the findings of the Womens Health Study
2. Womens heart risk underestimated by doctors, resulting in less preventive care than in men
3. Womens reproductive factors and the risk of rheumatoid arthritis
4. Childbirth and disasters discussed in July/Aug issue of Journal of Midwifery & Womens Health
5. Womens health research registry aims to improve womens health for future generations
6. Womens health research findings presented by University of Pittsburgh scientists
7. Womens group seeking nominations for annual media awards
8. Womens symptoms are new or different
9. American Medical Womens Association honors Dr. Marianne Legato with 2002 Women in Science Award
10. Womens and Childrens Hospital, Adelaide brings home national Diamond Serif Award
11. Older Womens Health Focus Of Bay Area Summit

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:11/19/2019)... ... November 19, 2019 , ... Bright Day Big Blocks, ... children is announcing the launch of their Gift Of Play initiative. Organizations are ... be theirs. , Co-Founders of Bright Day Big Blocks, Laurel Tucker and David Krishock ...
(Date:11/19/2019)... ... November 19, 2019 , ... iPatientCare, a pioneer ... Patient Engagement solutions, announces Virtual User Conference (VUCON), which will highlight the impact ... better patient-centric experience. , VUCON sessions are designed to demonstrate ...
(Date:11/16/2019)... VEGAS (PRWEB) , ... November 15, 2019 , ... ... seen before in the United States, access to cannabis via well-managed dispensaries becomes ... marijuana industry. Wise Business Plans, industry-leading online provider of state-of-the-art, online, custom cannabis ...
(Date:11/15/2019)... (PRWEB) , ... November 15, 2019 , ... ... over 100 employers in Newsday’s Top Long Island Workplaces for 2019. The recently ... , During the selection process, Newsday worked in partnership with Energage to conduct ...
(Date:11/14/2019)... ... 14, 2019 , ... EMulate Therapeutics, Inc., a clinical-stage therapeutic ... will have 5 poster presentations related to its medical devices for treating adult ... Meeting in Phoenix, beginning on November 20 . , Two posters ...
Breaking Medicine News(10 mins):
(Date:11/15/2019)... ... ... Unlike fine wine, shoulder joints do not get better with age. Risks ... – rise after age 50, says orthopedic surgeon Alejandro Badia MD , a ... uppermost tendon of the rotator cuff – the supraspinatus tendon and its lubricating tissue ...
(Date:11/15/2019)... ... , ... Mold doesn’t need things to be wet in order to grow; ... the eye or by touch. ServPro in Cayucos , the mold damage specialist, ... conditions that mold needs to grow and how to prevent those conditions. , Mold ...
(Date:11/14/2019)... ... November 14, 2019 , ... Algae Health Sciences, a division ... using AstaZine® on brain health. , In the first study (done ... fatigue and overall mood state [psychological well-being] were found after 8 weeks in ...
Breaking Medicine Technology:
Cached News: