HOME >> MEDICINE >> NEWS
Iris Murdoch's last novel reveals first signs of Alzheimer's disease

The last novel written by author Iris Murdoch before she died reveals signs of the first stages of Alzheimer's disease, according to a study published in the latest online issue of Brain.

As part of their on-going research into the effects of Alzheimer's disease on language, scientists at University College London and Medical Research Council's Cognition and Brain Sciences Unit decided to compare three of Dame Iris Murdoch's works, including her final novel written just before she was diagnosed with the disease.

The team found that, while the structure and grammar of Murdoch's writing remained roughly consistent throughout her career, her vocabulary had dwindled and her language simplified in her very last novel. This unique opportunity to study someone's writing style over their lifetime could help researchers improve current diagnostic tests for Alzheimer's.

Under the Net, Murdoch's first published work, The Sea, The Sea which was written during the prime of her creative life and her final novel, Jackson's Dilemma, written just before Murdoch was diagnosed with Alzheimer's disease, were all converted to digital format and analysed using specialised software. The complete texts were also transformed into word lists showing the frequency of each word by word-type.

The number of word types within a text is a measure of the variety of vocabulary used, and when examined at successive points in a text, reflects the rate at which the author introduces new words. In Murdoch's works, the smallest number of word-types occurred in Jackson's Dilemma and the largest in The Sea, The Sea. The rate of introduction of new word types was also strikingly greater in both earlier books compared with Jackson's Dilemma.

The findings suggest an enrichment in vocabulary between the early and middle stages of Murdoch's writing career, followed by an impoverishment before the composition of her final work. An examination of the character
'"/>

Contact: Jenny Gimpel
j.gimpel@ucl.ac.uk
44-207-679-9739
University College London
30-Nov-2004


Page: 1 2 3

Related medicine news :

1. Diagnosis of prions in patients should utilize novel strategy, team says
2. New math model of heart cell has novel calcium pathway
3. NIAID begins enrolling volunteers for novel HIV vaccine study
4. Scientists stalk PPAR-gamma, find novel cancer connection
5. Molecular tailoring of chemotherapy with novel imaging techniques
6. Two novel agents work synergistically to treat lung cancer in animal experiment
7. Fox Chase Cancer Center researchers identify novel target for detecting ovarian cancer in blood
8. LSUHSC neurosurgical team discovers novel therapy for intractable hiccups
9. Researchers identify novel method of distinguishing Alzheimers disease from other types of dementia
10. Jefferson researchers discover novel gene profile that may identify colon stem cells
11. Combination of toxin and poison may be novel treatment for leukemia

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/31/2020)... ... , ... Just found out your dear friend has cancer? , It’s hard to hear your ... shares their diagnosis. Once the shock wears off, the questions and fears can be overwhelming. ... best ways to help? Words are failing me. I’m scared. I want to DO something. ...
(Date:8/31/2020)... ... August 31, 2020 , ... Colorado State University Global (CSU ... affordable online education – is proud to announce its new master’s degree in ... its kind in the nation, the 60-credit hour program is designed to provide ...
(Date:8/31/2020)... ... August 31, 2020 , ... In an effort to give back to ... 10 percent of each hotel room booked with a special new rate code to ... Indiana (RMHC-CNI) , effective immediately. Donations will be applied to any room type, ...
(Date:8/28/2020)... ... 28, 2020 , ... Ernst & Young LLP (EY US) ... Of The Year® 2020 Florida Award finalist. Now in its 34th year, the ... growth and prosperity as they build and sustain successful businesses that transform our ...
(Date:8/28/2020)... (PRWEB) , ... August 28, 2020 , ... Integrated ... Miami is the first Florida school to deploy its breakthrough Mobile Biodefense Indoor Air ... airborne COVID-19. True North Classical Academy plans to fully reopen equipped with the filtration ...
Breaking Medicine News(10 mins):
(Date:9/1/2020)... ... September 01, 2020 , ... While coronavirus cases continue to increase across ... and community organizations remain closed. Because about 80% of blood donations are made at ... blood donors and blood drive hosts to ensure blood products are readily available for ...
(Date:8/31/2020)... (PRWEB) , ... August 31, 2020 , ... If you live in New York City ... real estate part makes sense, it’s the law of supply and demand, but are plastic ... has a significant percentage of their patients that make the four-hour trip to have ...
(Date:8/28/2020)... (PRWEB) , ... August 28, 2020 , ... Dr. ... reproductive and endoscopic surgeon and serves as a clinical professor in the Department of ... of the American Laparoscopy Society & Pacific Coast Reproductive Society and is a Clinical ...
Breaking Medicine Technology:
Cached News: