HOME >> MEDICINE >> NEWS
Jefferson and Molecular Targeting Technologies, Inc. scientists create vaccine for wildlife rabies

While the raccoon that raids your trash at night may look cute and mischievous, think again. Its claws can be nasty. Even worse, it might carry rabies.

Now, scientists at Jefferson Medical College in Philadelphia and at Molecular Targeting Technologies, Inc. (MTTI) in West Chester, Pa., are taking steps to prevent the disease. They have created a more powerful, safer vaccine than currently is available to combat rabies in wildlife.

Wildlife rabies is no small matter in this country. It's particularly prevalent along the East Coast, and more than 90 percent of reported cases of rabies in all are in wildlife. Raccoons are the most affected, with skunk a close second. Worldwide, and especially in underdeveloped nations, rabies takes a large human toll: More than 60,000 human deaths a year.

In work published December 9 in the journal Vaccine, researchers led by Bernhard Dietzschold, DVM, professor of microbiology and immunology at Jefferson Medical College of Thomas Jefferson University, created a new live rabies vaccine by manipulating the virus itself, making it much weaker than before. The scientists also made the vaccine much more immunogenic, meaning it aroused a much more robust response from the immune system.

"The advantages of our vaccine are its lack of pathogenicity and the fact that it's much more immunogenic," he says. Live virus vaccines always carry the potential to actually cause the disease they are designed to prevent.

"We have developed a very specific rabies vaccine which displays high titers and the lack of pathogenicity for immunocompetent mice even after many passages," says Dr. Dietzschold, meaning that the vaccine retained its potency over time. "This novel rabies vaccine will be an excellent candidate for immunization of stray dogs and wildlife."

"We have found a master key to turn on and off the pathogenicity of the virus," says Chris Pak, Ph.D., MTTI president and CEO. "We are extremely pleased with these p
'"/>


8-Dec-2004


Page: 1 2

Related medicine news :

1. Jefferson Lab medical imager spots breast cancer
2. Jefferson scientists uncover potential trigger of diabetic kidney disease
3. Uric acid may help reduce effects of spinal cord injury, Jefferson researchers find
4. Jefferson scientists help explain statins effects in Alzheimers disease
5. Jefferson scientists find zinc may help prevent esophageal, oral cancers
6. Jefferson virologists coax HIV out of hiding
7. Jefferson scientists find way to see breast cancer activity from outside the body
8. Jefferson scientists use gene therapy to rescue failing hearts in animals
9. Jefferson scientists reveal how some types of rabies invade the brain
10. Jefferson neuroscientists studying new type of Alzheimers drug to halt disease progression
11. Jefferson scientists uncover new evidence to help explain statins effects in Alzheimers disease

Post Your Comments:
(Date:8/30/2015)... , ... August 30, 2015 , ... ... (HIFU) medical devices for the treatment of prostate cancer, has announced the roll-out ... summer at the treatment center in Puerto Vallarta, Mexico. , The Sonablate® technology ...
(Date:8/29/2015)... ... August 30, 2015 , ... On September 30, 2015, the ... of the 10 regionally accredited Maricopa Community Colleges , will be hosting a ... students pursuing employment information and opportunities. , The Expo has expanded to much more ...
(Date:8/29/2015)... , ... August 29, 2015 , ... On Saturday, September ... Mesothelioma Applied Research Foundation (Meso Foundation) will present an educational program titled “Asbestos ... PM and lasts through 9:30 PM (doors open at 6:45pm) at Calvary United Methodist ...
(Date:8/29/2015)... ... August 29, 2015 , ... It can be uncomfortable ... dribbled urine and sweat. "In order to prevent these problems, I conceived of ... DRYNESS ENHANCED MEN'S UNDERGARMENT provides optimal support for a male’s crotch. It improves ...
(Date:8/29/2015)... CA (PRWEB) , ... August 29, 2015 , ... Dr. ... a mission. His mission is to increase acceptance of the chiropractic field in ... medications that further debilitate them. Although Chiropractic was made available to the VA ...
Breaking Medicine News(10 mins):Health News:Image Fusion Technology Combines MRI and Ultrasound Images to Treat Prostate Cancer 2Health News:Estrella Mountain Community College Expo Offers ‘One-Stop’ for Employers and Students Seeking Internships, Jobs, Careers and Service Learning Opportunities 2Health News:Mesothelioma Applied Research Foundation to Hold Educational Class About Asbestos and Mesothelioma Prevention 2Health News:Modified Men’s Underwear Promote More Comfort and Hygiene - Designed by InventHelp Client (LGI-1968) 2Health News:The Patriot Project brings Chiropractic Care to the Armed Forces and their Families - Rapid Release Technology Joins the Effort to Recruit more Doctors to Pledge 2
(Date:8/28/2015)... Aug. 28, 2015  Perrigo Company plc ("Perrigo") (NYSE: ... completed the acquisition of leading OTC brands from GSK ... The transaction is a clear demonstration of Perrigo,s unique ... European distribution network spanning 36 countries.  ... commented, "We are excited to complete this transaction, ...
(Date:8/28/2015)... 28 de agosto de 2015   Royal ... participación en el  Congreso de la ESC de ... recientes y novedosas, entre ellas HeartModel A.I.  , ... personas y la tecnología con los protocolos de ... los tratamientos y permitir atención en el hogar. ...
(Date:8/27/2015)... CUPERTINO, Calif. , Aug. 27, 2015 ... management is scheduled to present at three upcoming healthcare ... , President and CEO, will present at the Rodman ... 10:00 a.m. Eastern time. The conference is being held ... York City . A live audio webcast of ...
Breaking Medicine Technology:Perrigo Completes Acquisition of Leading Portfolio of OTC Brands from GSK 2Perrigo Completes Acquisition of Leading Portfolio of OTC Brands from GSK 3Perrigo Completes Acquisition of Leading Portfolio of OTC Brands from GSK 4Philips presenta nuevas soluciones cardiológicas integradas para desarrollar procedimientos menos invasivos 2Philips presenta nuevas soluciones cardiológicas integradas para desarrollar procedimientos menos invasivos 3Philips presenta nuevas soluciones cardiológicas integradas para desarrollar procedimientos menos invasivos 4Philips presenta nuevas soluciones cardiológicas integradas para desarrollar procedimientos menos invasivos 5DURECT to Participate in Upcoming Healthcare Conferences 2
Cached News: