HOME >> MEDICINE >> NEWS
Jefferson and Molecular Targeting Technologies, Inc. scientists create vaccine for wildlife rabies

While the raccoon that raids your trash at night may look cute and mischievous, think again. Its claws can be nasty. Even worse, it might carry rabies.

Now, scientists at Jefferson Medical College in Philadelphia and at Molecular Targeting Technologies, Inc. (MTTI) in West Chester, Pa., are taking steps to prevent the disease. They have created a more powerful, safer vaccine than currently is available to combat rabies in wildlife.

Wildlife rabies is no small matter in this country. It's particularly prevalent along the East Coast, and more than 90 percent of reported cases of rabies in all are in wildlife. Raccoons are the most affected, with skunk a close second. Worldwide, and especially in underdeveloped nations, rabies takes a large human toll: More than 60,000 human deaths a year.

In work published December 9 in the journal Vaccine, researchers led by Bernhard Dietzschold, DVM, professor of microbiology and immunology at Jefferson Medical College of Thomas Jefferson University, created a new live rabies vaccine by manipulating the virus itself, making it much weaker than before. The scientists also made the vaccine much more immunogenic, meaning it aroused a much more robust response from the immune system.

"The advantages of our vaccine are its lack of pathogenicity and the fact that it's much more immunogenic," he says. Live virus vaccines always carry the potential to actually cause the disease they are designed to prevent.

"We have developed a very specific rabies vaccine which displays high titers and the lack of pathogenicity for immunocompetent mice even after many passages," says Dr. Dietzschold, meaning that the vaccine retained its potency over time. "This novel rabies vaccine will be an excellent candidate for immunization of stray dogs and wildlife."

"We have found a master key to turn on and off the pathogenicity of the virus," says Chris Pak, Ph.D., MTTI president and CEO. "We are extremely pleased with these p
'"/>


8-Dec-2004


Page: 1 2

Related medicine news :

1. Jefferson Lab medical imager spots breast cancer
2. Jefferson scientists uncover potential trigger of diabetic kidney disease
3. Uric acid may help reduce effects of spinal cord injury, Jefferson researchers find
4. Jefferson scientists help explain statins effects in Alzheimers disease
5. Jefferson scientists find zinc may help prevent esophageal, oral cancers
6. Jefferson virologists coax HIV out of hiding
7. Jefferson scientists find way to see breast cancer activity from outside the body
8. Jefferson scientists use gene therapy to rescue failing hearts in animals
9. Jefferson scientists reveal how some types of rabies invade the brain
10. Jefferson neuroscientists studying new type of Alzheimers drug to halt disease progression
11. Jefferson scientists uncover new evidence to help explain statins effects in Alzheimers disease

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/13/2017)... ... October 13, 2017 , ... “America On The Brink”: ... “America On The Brink” is the creation of published author, William Nowers. ... As a WWII veteran, he spent thirty years in the Navy. Following ...
(Date:10/12/2017)... LA (PRWEB) , ... October 12, 2017 , ... Planet ... in the U.S., announced today its plans to open a flagship location in Covington, ... occupy the former Rooms To Go store next to Office Depot in the Holiday ...
(Date:10/12/2017)... ... ... The American College of Medical Informatics (ACMI) will present the 2017 Morris ... of AMIA’s Annual Symposium in Washington, D.C. AMIA’s Annual Symposium is taking ... in the field of medical informatics, this prestigious award is presented to an individual ...
(Date:10/12/2017)... ... October 12, 2017 , ... Dr. ... recently contributed a medical article to the newly revamped Cosmetic Town journal ... spotlights the hair transplant procedure known as Follicular Unit Extraction (FUE). ...
(Date:10/12/2017)... ... 12, 2017 , ... On Saturday, October 21, the Health & Wellness Center ... to raise money for the American Heart Association Heart Walk. Teams of up to ... together to keep their treadmills moving for 5 hours. Treadmills will start at 7:00 ...
Breaking Medicine News(10 mins):
(Date:10/12/2017)... 2017 AVACEN Medical , Inc. (AVACEN) announced ... 2017 New Product Innovation Award for Its fibromyalgia pain ... secondary medical device market research by Frost & Sullivan,s industry ... drug-free pain relief product, the AVACEN 100, offers a safe ... widespread pain. ...
(Date:10/11/2017)... Calif. , Oct. 11, 2017  BioPharmX Corporation ... scientific team that developed an innovative way to use ... of the delivery of new drugs. ... Fall Clinical Dermatology Conference will show how researchers from ... Hospital, Harvard Medical School used a suite of imaging ...
(Date:10/11/2017)... 2017  Hill-Rom Holdings, Inc. ("Hill-Rom") (NYSE: HRC), today ... Las Piedras, Puerto Rico , where ... Following a comprehensive ... minor structural damage, temporary loss of power and minimal ... completed, manufacturing operations have resumed, and the company expects ...
Breaking Medicine Technology:
Cached News: