Jefferson researchers discover novel gene profile that may identify colon ...( ene involved in the formation of the gu...)

Jefferson researchers discover novel gene profile that may identify colon stem cells

ene involved in the formation of the gut.

Stem cells in the normal colon produce daughter cells that proliferate and make their way to the crypt top, where they differentiate into specialized colon cells, says Dr. Boman. Colon cancer is marked by a change in the distribution pattern of proliferating daughter cells. Next, the researchers plan to use their novel gene profile to investigate cellular changes in colon cancer development. They also plan to use a different microarray to expand the number of genes they can examine.

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30-Mar-2004

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