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Keep an eye on the weather if you take herbal antidepressants

develop inflamed and swollen tissues that make swallowing and breathing difficult.

David Wheatley, a psychiatrist at the Charter Chelsea Clinic in London, says he has had no complaints from his patients about side effects while taking St John's wort. "It works extremely well for people with mild to moderate depression," he says.

But Geoffrey Bove, a neurophysiologist at Harvard Medical School, has treated a patient who developed intense pain in areas exposed to the sun while taking St John's wort (The Lancet, vol 352, p 1121). Bove believes that free radicals generated by hypericin resulted in the damage to the patient's nerve cells.

There may be a silver lining lurking in the herb's side effect, however. Hypericin's strong reaction with light is currently being investigated as a treatment for some skin cancers. "Its side effect is being used as a potential therapy for killing cancer cells," says Roberts.


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Contact: Claire Bowles
claire.bowles@rbi.co.uk
44-171-331-2751
New Scientist
21-Jul-1999


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