Speaking today, Professor Pepys said:
'Our experimental studies identified SAP as a key suspect in the development of amyloidosis and we aimed to find a drug that could block its effects.
'Remarkably our drug produces a complete knockout of the single protein in the blood that we targeted. It's the first time that this has been achieved with a small molecule drug. Understanding the way the drug works suggests applications of the mechanism we have discovered to other proteins in the blood that contribute to many different diseases.'
Professor Pepys continued:
'Although amyloid deposits are closely associated with Alzheimer's disease and maturity onset diabetes, it is not known whether they actually cause these diseases. But there is no doubt that our work offers real hope for systemic amyloidosis, a very serious conditions which, until now, has been difficult and dangerous to treat.'