HOME >> MEDICINE >> NEWS
Lack Of Data For New Heart Drugs Is Causing Concern


Trial And Error

ONE of the researchers who exposed the dangers of using albumin in patients suffering from serious burns or shock says new drugs for high blood pressure face unanswered questions regarding their safety.

Two weeks ago, Ian Roberts of the Institute of Child Health in London and his colleagues said in the British Medical Journal (vol 317, p 235) that albumin, which has been in use for more than 30 years, claims more lives than it saves. After an analysis of patient records, they concluded that it causes around 1200 extra deaths in critically ill patients in Britain each year.

Now one of the team, Alain Li Wan Po of Nottingham University, says data on the safety of six drugs to treat high blood pressure, which have or are about to get licences in Britain, are inadequate. Li Wan Po has been involved in safety testing of some of the drugs. They are all a new class of "centrally acting antihypertensives", which target receptors in the brainstem that orchestrate the dilation of blood vessels.

One of the drugs, moxonidine, is already licensed in Britain. Li Wan Po cannot name the others because he has signed confidentiality agreements while working on the safety studies.

He believes the licensing regulations are not strict enough to ensure the six drugs are safe. Large-scale controlled trials of the drugs took place for three to four years. But Li Wan Po says only controlled trials over decades will reveal whether the new drugs reduce heart attacks, strokes and deaths. Brian Pentecost, medical director of the British Heart Foundation and a member of Britain's Committee on the Safety of Medicines, agrees that the lack of controlled data for newer heart drugs is "a cause for concern".

But Lawrence Ramsay, a specialist in heart drugs at Sheffield University, suggests it is unreasonable to expect drugs companies, which may have invested hundreds of millions of pounds d
'"/>

Contact: Claire Bowles
claire.bowles@rbi.co.uk
44 171 331 2751
New Scientist
5-Aug-1998


Page: 1 2

Related medicine news :

1. The European Society of Cardiology launches Women at Heart
2. Heart surgeons publish death rates
3. Heart attack treatment gap may be closing for women
4. The Larry King Cardiac Foundation presents The Changing Face of Heart Disease on Feb. 2
5. Brenner Childrens Hospital named to NIH Pediatric Heart Network
6. Heart patients treated by non-cardiologists less likely to receive medications
7. Heart failure patients treated for diabetes with insulin have increase in mortality
8. New research results: Heart jacket shown to be effective
9. Heart surgery patients receive less aggressive discharge care
10. Heart attack, stroke risk overlooked in diabetics
11. Heart arrhythmias easily treated, yet few know risks

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/28/2020)... ... August 28, 2020 , ... The 15 scholarships ... Lighthouse Health & Wellness mobile app and web-portal. NCPCV received a 2020 grant ... awards grants each year to organizations, such as Destination Imagination, which support and ...
(Date:8/28/2020)... ... August 28, 2020 , ... Integrated Viral Protection ... first Florida school to deploy its breakthrough Mobile Biodefense Indoor Air Protection System that ... North Classical Academy plans to fully reopen equipped with the filtration system on September ...
(Date:8/28/2020)... , ... August 28, 2020 , ... ... observations that strongly suggest that obese individuals are at an increased risk of ... any more likely to catch COVID-19; however, because the same organ systems that ...
(Date:8/27/2020)... , ... August 27, 2020 , ... ... Sikara Medspa is a leading aesthetic and wellness retreat. The practice is centered ... surrounding areas of Las Vegas. , Designed to be a sanctuary for ...
(Date:8/26/2020)... ... August 26, 2020 , ... Smile Brands Inc. CEO, ... Online Forum, leading a session entitled, “A CEO Guide for Delivering and Measuring ... designed to bring together the world’s leading diversity and inclusion executives, HR consultants, ...
Breaking Medicine News(10 mins):
(Date:8/26/2020)... ... , ... As the U.S. struggles in its 6th month of fighting Covid-19, ... a mask, keep your distance, wash your hands. Prevention is the best tool for ... 1977, “How much better it is to prevent disease than to cure it.” , ...
(Date:8/26/2020)... Calif. (PRWEB) , ... August 26, 2020 , ... ... to a target goal of 115 million 3 ply surgical disposable face masks and ... production is in direct response to the challenge that most Americans are facing in ...
(Date:8/26/2020)... ... August 26, 2020 , ... NucleusHealth, ... Claude E. Hooton as President and Chief Executive Officer effective immediately. Dr. Vishal ... the company’s Board of Managers. , Mr. Hooton, a seasoned business executive, ...
Breaking Medicine Technology:
Cached News: