HOME >> MEDICINE >> NEWS
Leading cancer doctor calls for new guidelines to control early reporting from clinical trials

Hamburg, Germany: A leading breast cancer doctor is urging researchers to consider changing the guidelines that govern whether clinical trials should be stopped prematurely, as she believes that current practice could be damaging research efforts.

Dr Martine Piccart, head of the chemotherapy unit at the Institut Jules Bordet, Brussels, Belgium, is putting proposals for new guidelines to the Breast International Group (BIG) and, if BIG agrees, the issue would be discussed with the North American Breast Intergroup.

She said that breast cancer research had not been well served by trials of adjuvant therapies aimed at preventing cancer returning, which had reported their results early, because this could mean that some questions about long-term efficacy and side effects or untoward effects remained unanswered, and the future of other trials was put at risk.

"Researchers need to achieve a better balance between informing doctors and women quickly about a more effective treatment for breast cancer and the equally important need to collect solid data on the safety of the therapy," she told a discussion group at the 4th European Breast Cancer.

Three recent trials* of aromatase inhibitors (AIs) as adjuvant treatments for breast cancer had all reported results early because they showed significant advantages for AIs over tamoxifen, but Dr Piccart said that an average follow-up time of only 30 months did not enable doctors to weigh up the long-term risks and benefits of the different treatments. If the trials had continued for longer it was possible that the risks of the different treatments would have become clearer (for instance, tamoxifen carries a risk of endometrial cancer and blood clots, whereas AIs carry a risk of osteoporosis and bone fractures), therefore allowing doctors to conduct a useful risk-benefit analysis an integral part of making appropriate decisions about the best treatment for a patient.

She said early reporting
'"/>

Contact: Emma Mason
wordmason@aol.com
49-403-569-3625
Federation of European Cancer Societies
18-Mar-2004


Page: 1 2 3

Related medicine news :

1. Leading researchers in allergic disease to gather for 2005 AAAAI Annual Meeting
2. Leading tobacco manufacturer conceals links to tobacco research facility
3. Leading MRSA experts address emergence of superbug
4. Leading causes of blindness for blacks and whites different
5. Leading AIDS experts criticize US-sponsored HIV vaccine trial in Thailand
6. Leading the way in novel anti-cancer research
7. Leading American, German chemists converge to share research, vision
8. Leading anti-cancer factions strengthen bonds
9. Leading NIH-funded medical schools agree on guidelines that would strenghten conflict of interest policies
10. Biochemical Marker Targets Brain Injury Leading To Movement Problems After Stroke
11. New Model Shows How To Eradicate Worlds Leading Infectious Cause Of Blindness

Post Your Comments:
(Date:10/31/2014)... DARIEN, IL – New research suggests that insomnia is ... crashes and other unintentional fatal injuries. The results underscore ... of the National Healthy Sleep Awareness Project. , Results ... in a dose-dependent manner with the number of insomnia ... were 2.8 times more likely to die from a ...
(Date:10/31/2014)... Barbara, CA (PRWEB) October 31, 2014 ... holiday shoppers to find affordable but tasteful gifts for the ... 22nd Annual Early Bird Gift Giving Special , which ... off when they purchase Wine Club Gift membership. , ... take advantage of this special. Besides offering discounts, Gold Medal ...
(Date:10/31/2014)... Urban Hydroponics, Inc. (OTCQB:URHY), a Nevada corporation ... signed a Binding Letter of Intent (LOI) to merge ... - Urban Cultivator Inc. (“Urban Cultivator”), BC Northern Lights ... (“W3 Metal” and together with Urban Cultivator and BC ... LOI and an earlier non-binding term sheet, Urban Hydroponics, ...
(Date:10/31/2014)... New York, NY (PRWEB) October 31, 2014 ... on one of the most remarkable gifts of life ... a platform for matching extraordinary surrogate mothers and donors ... stories about individuals in unforeseen circumstances. , It’s a ... sperm donors, surrogacy agencies, surrogacy lawyers, and fertility clinics ...
(Date:10/31/2014)... Phoenix dentist , Dr. Christy, is now ... patients simply need routine care or have a more in-depth ... to get that necessary care. The right dental treatments can ... even essential treatments due to financial concerns. Throughout the month ... treatments offered by the team at Christy Dental Care. ...
Breaking Medicine News(10 mins):Health News:Insomnia increases risk of motor vehicle deaths, other fatal injuries 2Health News:Gold Medal Wine Club now offering Early Bird Gift Giving Special for Holidays 2Health News:Urban Hydroponics Inc. Signs Definitive Agreement to Merge with Canadian Hydroponics Companies 2Health News:Urban Hydroponics Inc. Signs Definitive Agreement to Merge with Canadian Hydroponics Companies 3Health News:Urban Hydroponics Inc. Signs Definitive Agreement to Merge with Canadian Hydroponics Companies 4Health News:Urban Hydroponics Inc. Signs Definitive Agreement to Merge with Canadian Hydroponics Companies 5Health News:Over 800 New Surrogate Mother Members at FindSurrogateMother.com Helping Create Pathways to Parenthood 2Health News:Over 800 New Surrogate Mother Members at FindSurrogateMother.com Helping Create Pathways to Parenthood 3Health News:Phoenix Dentist, Dr. Christy, is Now Offering Ten Percent Off On All Dental Treatments for the Month of November 2
(Date:10/31/2014)... /CNW Telbec/ - Ergoresearch Ltd ("Ergoresearch" or ... accelerated growth in terms of sales and profitability. Annual ... Net income amounted to $1,230,153. The EBITDA reached $3,087,816, ... in the Company,s history. With the goal ... of its subsidiaries, merging in September 2014 Clinique du ...
(Date:10/31/2014)... Oct. 31, 2014  Isis Pharmaceuticals, Inc. (NASDAQ: ...  What: , Isis Pharmaceuticals, Third Quarter 2014 Financial ... 7 at 11:30 a.m. ET / 8:30 a.m. PTWhere: ... the Internet. Simply log onto our website listed above. ... event, a replay of the webcast will be available ...
(Date:10/30/2014)... -- Misonix, Inc. (NASDAQ: MSON ), an international ... innovative therapeutic ultrasonic instruments for spine surgery, neurosurgery and ... financial results for the first quarter fiscal year 2015 ... a conference call that same day, Thursday, November 6, ... Interested parties can access the conference ...
Breaking Medicine Technology:Results for the fourth quarter and the fiscal year ended June 30, 2014 - Ergoresearch reports solid 2014 annual results 2Results for the fourth quarter and the fiscal year ended June 30, 2014 - Ergoresearch reports solid 2014 annual results 3Results for the fourth quarter and the fiscal year ended June 30, 2014 - Ergoresearch reports solid 2014 annual results 4Results for the fourth quarter and the fiscal year ended June 30, 2014 - Ergoresearch reports solid 2014 annual results 5Webcast Alert: Isis Pharmaceuticals' Third Quarter 2014 Financial Results Conference Call 2Webcast Alert: Isis Pharmaceuticals' Third Quarter 2014 Financial Results Conference Call 3Misonix, Inc. To Report First Quarter Fiscal Year 2015 Financial Results On Thursday, November 6, 2014 2
Cached News: