HOME >> MEDICINE >> NEWS
Leading cancer doctor calls for new guidelines to control early reporting from clinical trials

Hamburg, Germany: A leading breast cancer doctor is urging researchers to consider changing the guidelines that govern whether clinical trials should be stopped prematurely, as she believes that current practice could be damaging research efforts.

Dr Martine Piccart, head of the chemotherapy unit at the Institut Jules Bordet, Brussels, Belgium, is putting proposals for new guidelines to the Breast International Group (BIG) and, if BIG agrees, the issue would be discussed with the North American Breast Intergroup.

She said that breast cancer research had not been well served by trials of adjuvant therapies aimed at preventing cancer returning, which had reported their results early, because this could mean that some questions about long-term efficacy and side effects or untoward effects remained unanswered, and the future of other trials was put at risk.

"Researchers need to achieve a better balance between informing doctors and women quickly about a more effective treatment for breast cancer and the equally important need to collect solid data on the safety of the therapy," she told a discussion group at the 4th European Breast Cancer.

Three recent trials* of aromatase inhibitors (AIs) as adjuvant treatments for breast cancer had all reported results early because they showed significant advantages for AIs over tamoxifen, but Dr Piccart said that an average follow-up time of only 30 months did not enable doctors to weigh up the long-term risks and benefits of the different treatments. If the trials had continued for longer it was possible that the risks of the different treatments would have become clearer (for instance, tamoxifen carries a risk of endometrial cancer and blood clots, whereas AIs carry a risk of osteoporosis and bone fractures), therefore allowing doctors to conduct a useful risk-benefit analysis an integral part of making appropriate decisions about the best treatment for a patient.

She said early reporting
'"/>

Contact: Emma Mason
wordmason@aol.com
49-403-569-3625
Federation of European Cancer Societies
18-Mar-2004


Page: 1 2 3

Related medicine news :

1. Leading researchers in allergic disease to gather for 2005 AAAAI Annual Meeting
2. Leading tobacco manufacturer conceals links to tobacco research facility
3. Leading MRSA experts address emergence of superbug
4. Leading causes of blindness for blacks and whites different
5. Leading AIDS experts criticize US-sponsored HIV vaccine trial in Thailand
6. Leading the way in novel anti-cancer research
7. Leading American, German chemists converge to share research, vision
8. Leading anti-cancer factions strengthen bonds
9. Leading NIH-funded medical schools agree on guidelines that would strenghten conflict of interest policies
10. Biochemical Marker Targets Brain Injury Leading To Movement Problems After Stroke
11. New Model Shows How To Eradicate Worlds Leading Infectious Cause Of Blindness

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/24/2017)... ... ... Pink , a national non-profit organization focusing on the prevention and early detection of breast ... proud to announce Katie Thiede as their new Chief Executive Officer. In January, founder Lindsay ... the Board and launched a national search to find a visionary new leader to grow ...
(Date:4/24/2017)... ... April 24, 2017 , ... ALP ... food supplements, announced its popular products are now available for purchase on StackedNutrition.com, ... prioritizes the use of premium natural ingredients in making all of its products. ...
(Date:4/24/2017)... NEW PORT RICHEY, Fla. (PRWEB) , ... April ... ... Disease Control and Prevention (CDC), rising prescription opioid overdose deaths now claim the ... (DEA) has slashed its civil case filings against drug manufacturers, distributors, pharmacies and ...
(Date:4/24/2017)... ... 2017 , ... As a former supermodel known for her timeless beauty, Joan ... single women is that she put all the words in her new book, "Manifest ... personal experiences and sparkling sense of humor have inspired her to write a book ...
(Date:4/24/2017)... ... ... “Reflections of God’s Work”: an enlightening collection of life lessons leading each ... published author, Jerri Broglin, a survivor of great loss who gained insight on how ... for those searching for answers, as we are finding the answers that are so ...
Breaking Medicine News(10 mins):
(Date:4/19/2017)... , April 19, 2017 /PRNewswire/ - CRH Medical Corporation (TSX: CRH) (NYSE ... Bloom Burton & Co. Healthcare Investor Conference 2017 at the Sheraton ... Edward Wright , Chief Executive Officer of the Company is scheduled ... CFO, Richard Bear and the Chairman of the Board, ... ...
(Date:4/19/2017)... Global Surgical Drainage Device Market: Overview ... remove excess liquid and air. The fluid to be ... lymph. Surgical drains are used in a wide variety ... cardiovascular surgery, neurosurgery, plastic surgery etc. Common use of ... of fluid e.g. blood or pus. Surgical drains are ...
(Date:4/19/2017)... DIEGO , April 19, 2017  Sorrento ... an antibody-centric, clinical-stage biopharmaceutical company developing new treatments ... announced the closing of its previously announced underwritten ... stock at a public offering price of $2.00 ... and estimated offering expenses payable by Sorrento.  The ...
Breaking Medicine Technology:
Cached News: