HOME >> MEDICINE >> NEWS
Leading the way in novel anti-cancer research

Boston, MA -- New research presented today at an official AACR-NCI-EORTC* press conference highlights the potential of a new approach to fighting cancer -- inhibition of Aurora kinases. The study, carried out by AstraZeneca, represents part of a body of innovative research and discovery work undertaken by the company as part of a broad based development program of novel cancer therapies. Key research presented this week also includes results from a study combining two agents developed by AstraZeneca: an epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor and the vascular targeting agent ZD6126.

New frontiers in cancer biology inhibition of Aurora kinases:

The Aurora kinase family is important in regulating mitosis and cell division. Because these kinases are only expressed in cells that are actively dividing, they could be an important new target in cancer. Aurora kinases are commonly over expressed in breast, colon, pancreas and bladder tumors and this is correlated with poor prognosis in these diseases. AstraZeneca scientists have discovered selective and potent inhibitors of Aurora kinase activity that may have potential application in human cancer treatment. These inhibitors of Aurora kinase are being investigated to ascertain their potential in the treatment of cancer.

"Through cutting-edge research and development, AstraZeneca hopes to achieve a better understanding of Aurora kinases and their regulation, which could in time be a basis for treating or even preventing cancer," said George Blackledge, Vice President, Medical Director of Oncology, AstraZeneca. "This is part of a broad based development program in cell cycle directed therapies."

Leading the way in combining novel anti-cancer approaches:

New pre-clinical research presented at the meeting shows that combining a vascular targeting agent with an EGFR tyrosine kinase inhibitor may result in greater anti-tumor activity than
'"/>

Contact: Emily Denney
emily.denney@astrazeneca.com
302-885-3451
AstraZeneca
19-Nov-2003


Page: 1 2 3

Related medicine news :

1. Leading researchers in allergic disease to gather for 2005 AAAAI Annual Meeting
2. Leading tobacco manufacturer conceals links to tobacco research facility
3. Leading MRSA experts address emergence of superbug
4. Leading causes of blindness for blacks and whites different
5. Leading cancer doctor calls for new guidelines to control early reporting from clinical trials
6. Leading AIDS experts criticize US-sponsored HIV vaccine trial in Thailand
7. Leading American, German chemists converge to share research, vision
8. Leading anti-cancer factions strengthen bonds
9. Leading NIH-funded medical schools agree on guidelines that would strenghten conflict of interest policies
10. Biochemical Marker Targets Brain Injury Leading To Movement Problems After Stroke
11. New Model Shows How To Eradicate Worlds Leading Infectious Cause Of Blindness

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:12/14/2019)... ... 14, 2019 , ... For two years, the only hospital in the Middle ... the parking lot would make you think of the temporary buildings you would see ... devastated the old building and the hospital carried on, first in tents and then ...
(Date:12/9/2019)... , ... December 09, 2019 , ... WEDI , ... in health care information exchange and a trusted advisor to the U.S. Department of ... to its Board of Directors, election of Officers* as well as the re-election of ...
(Date:12/9/2019)... ... ... OCLI, a Spectrum Vision Partners (SVP) managed practice, has announced the addition ... practice with experience spanning decades. As part of OCLI, Drs. Cary Silverman, Nicholas Xanthos ... 46 Eagle Rock Ave, East Hanover, NJ 07936. , Over the past ...
(Date:12/8/2019)... ... December 07, 2019 , ... Intelligent.com, a trusted ... 55 Best Master of Science in Nursing (MSN) Degree Programs for 2020. The ... universities in the nation. Each program is evaluated based on curriculum quality, graduation ...
(Date:12/6/2019)... (PRWEB) , ... December 06, 2019 , ... ... recruiting, has been recognized for excellence in employee learning. The Omaha-based company has ... ranks organizations with the most successful employer-sponsored training and development programs worldwide. Rankings ...
Breaking Medicine News(10 mins):
(Date:12/6/2019)... , ... December 06, 2019 , ... ... development of treatments for psychiatric and neurodegenerative disorders, announced today that the U.S. ... for NBTX-001 Inhaler, allowing the Company to initiate its Phase 2b trial for ...
(Date:12/6/2019)... ... December 06, 2019 , ... Food and nutrition industry ... and ideas about working toward sustainable nutrition security nationwide, increasing accessibility to nutritious ... develop a healthy and sustainable food system,” said Carol May, CEO of Wisdom ...
(Date:12/6/2019)... , ... December 06, 2019 , ... ... agreement with Forbidden Fruit Garden Supply LLC (a division of Horticultural Holdings LLC) ... clientele of professional growers. , FFGS is a team of disciplined and ...
Breaking Medicine Technology:
Cached News: