Linezolid is superior treatment for drug-resistant pneumonia

St. Louis, March 2, 2004 -- A relatively new drug called linezolid (commercially known as Zyvox) appears to be about 40 percent more effective in treating a deadly and increasingly prevalent form of antibiotic-resistant pneumonia than the conventionally used drug vancomycin, according to a team led by researchers at Washington University School of Medicine in St. Louis.

Combined analysis of two studies comparing the drugs appears online in the journal Intensive Care Medicine and is expected to be published in print March 8. The paper represents the largest group of patients ever studied with this form of pneumonia, called ventilator-associated pneumonia caused by methicillin-resistant Staphylococcus aureus (MRSA). Once primarily associated with intensive care units, the strain has become increasingly common in the general population, particularly in children.

"The reality is medicine is falling behind infectious organisms," says principal investigator Marin H. Kollef, M.D., associate professor of medicine. "Our results are encouraging, though, because they suggest linezolid succeeds in penetrating the lungs and eradicating a particularly resilient form of bacterial infection."

Pharmacia Corp., now part of Pfizer Inc., funded the research. Both studies included in the analysis were "double-blind," meaning neither the treating physicians nor the patients knew which medication was being administered.

Hospitalized patients often develop bacterial infections such as pneumonia. Individuals using ventilators for breathing support are particularly vulnerable, because bacteria can enter the lungs through the breathing tube. Ventilator-associated pneumonia is estimated to result in about 1.75 million additional hospital days each year.

Further complicating the issue, many bacteria have become resistant to medicine's standard arsenal of antibiotic treatments. MRSA is one of the more common and lethal forms of drug-resistant pneumonia.

Contact: Gila Z. Reckess
Washington University School of Medicine

Page: 1 2 3

Related medicine news :

1. Kinder, gentler procedure gives superior results for stem cell transplants
2. Therapy, medication combination superior for children with obsessive-compulsive disorder
3. Universit de Montral study shows superior sound-location skills in the blind
4. CellCept(R) registry data demonstrated superior long-term organ transplant outcomes
5. Wavefront LASIK demonstrated superior to conventional LASIK
6. Transvaginal ultrasound superior to transrectal ultrasound for staging rectal cancer in women
7. MRI superior to ultrasound in predicting cerebral palsy in preterm infants
8. Mycophenolate mofetil superior to azathioprine: Slows vascular disease progression after transplant
9. PET scans superior in revealing response to treatment for gastrointestinal stromal tumors
10. Endovascular coil superior to neurosurgery for treatment of brain haemorrhage
11. Secret agents secret revealed - shaken martinis have superior antioxidant properties to those that are stirred

Post Your Comments:

(Date:12/8/2019)... ... 08, 2019 , ... Intelligent.com, a trusted resource for online ... Programs for 2020. The comprehensive research guide is based on an assessment of ... on curriculum quality, graduation rate, reputation, and post-graduate employment. , The 2020 ...
(Date:12/6/2019)... ... December 06, 2019 , ... Connecticut is home ... excellence in patient care. On December 12th, Hartford Business Journal will recognize eight ... Care Heroes Awards at the Hartford Marriott. , “We are fortunate to have ...
(Date:12/6/2019)... ... December 06, 2019 , ... ... HIPAA compliance solution for the Wyoming Medical Society. Compliancy Group is dedicated to ... entities have an obligation to adhere to the standards set forth by the ...
(Date:12/5/2019)... ... December 05, 2019 , ... A cohort of ... technology to help their patients more easily detect ruptured silicone gel implants. Dr. ... study and reporting on his experience. While the FDA currently recommends regular MRI ...
(Date:12/5/2019)... , ... December 05, 2019 , ... ... milestones ranging from launching exceptional products that help people embrace, achieve, and maintain ... , “We’ve never been more committed to our mission of impacting world health, ...
Breaking Medicine News(10 mins):
(Date:12/6/2019)... (PRWEB) , ... December 06, 2019 , ... ... on development of treatments for psychiatric and neurodegenerative disorders, announced today that the ... application for NBTX-001 Inhaler, allowing the Company to initiate its Phase 2b trial ...
(Date:12/6/2019)... GILBERT, Ariz. (PRWEB) , ... December 06, 2019 ... ... the Industry Nutrition Forum in Philadelphia to share information and ideas about working ... percentage of the population. , “It’s vital that we develop a healthy and ...
(Date:12/6/2019)... , ... December 06, 2019 , ... ... agreement with Forbidden Fruit Garden Supply LLC (a division of Horticultural Holdings LLC) ... clientele of professional growers. , FFGS is a team of disciplined and ...
Breaking Medicine Technology:
Cached News: