HOME >> MEDICINE >> NEWS
Long-term benefits found in two drugs for Parkinson's

Two drugs used to treat hallucinations in patients with Parkinsons disease (PD) can not only reduce hallucinations, but may also lead to long-term benefits in these patients, according to a group of Emory University researchers. The long-term benefits may include reduced mortality and a reduced risk of nursing home placement. The drugs studied were the atypical antipsychotics quetiapine (trade name Seroquel) and clozapine (trade name Clozaril).

Jorge Juncos, M.D., associate professor of neurology, Emory University School of Medicine, and colleagues will present their findings at the American Academy of Neurology 54th Annual Meeting in Denver, Colo., on April 18. The research will also appear as an abstract in the April issue of the journal, Neurology.

"Drug-induced psychotic symptoms, such as visual hallucinations, are seen in a significant number of patients with advanced PD," says Dr. Juncos. "Approximately 15 to 20 percent of PD patients may experience these hallucinations over time. They are due to a interaction between the progression of the illness and the drugs used to treat its symptoms," Dr. Juncos explains.

The Emory researchers conducted a retrospective chart review between 1996 and 2001 in 27 patients with advanced PD (mean duration of illness of 13 years, plus or minus six years). Hallucinations had been treated for approximately 36 months using quetiapine in 23 patients and clozapine in four patients.

"We compared the antipsychotic efficacy, mortality and risk of nursing home placement to published historical data (Goetz & Stebbins, Neurology 1996) in similarly affected patients treated with low doses of typical anti-psychotics before 1996," Dr. Juncos says.

Based on clinical exams or caregiver reports, Emory researchers found hallucinations in these patients were reduced by almost half (from 100 to 59 percent) while patients were on one of the study medications. Symptoms of agitation were also re
'"/>

Contact: Janet Christenbury
jmchris@emory.edu
404-727-8599
Emory University Health Sciences Center
18-Apr-2002


Page: 1 2

Related medicine news :

1. Long-term high consumption of red and processed meat linked with increased risk for colon cancer
2. Long-term data show benefit of DETROL LA as first-line therapy for overactive bladder
3. Long-term benefits for newly diagnosed patients with CML receiving first-line therapy with imatinib
4. Long-term obesity linked to loss of brain tissue in women
5. Long-term study demonstrated ADDERALL XR is an effective option to treat adolescents with ADHA
6. Long-term study proves ADDERALL XR is a safe and effective option to treat adults with ADHD
7. Long-term use of antibiotics possibly linked with increased risk of breast cancer
8. Long-term follow-up of mortality in patients with community-acquired pneumonia
9. Long-term outcome of epilepsy surgery is favorable for many
10. Long-term ERT in postmenopausal women with Alzheimers may worsen memory
11. Long-term avoidance of milk in children results in poor bone health

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/5/2016)... (PRWEB) , ... May 05, 2016 , ... ... Unites States to promise successful results with IVF and with egg freezing, today ... deliver the most patient-centric and highest quality fertility care, Spring Fertility offers both ...
(Date:5/5/2016)... , ... May 05, 2016 , ... Derrin Doty Group ... families of Bremerton, Port Orchard and communities west of Seattle. The insurance provider’s caring ... year local girl who died suddenly due to complications from the flu, that they ...
(Date:5/5/2016)... (PRWEB) , ... May 05, 2016 , ... A recent ... continue to face challenges in getting employees to understand and use the free preventive ... of the nation’s leading non-profit business groups of large, self-insured public and private employers, ...
(Date:5/5/2016)... ... May 05, 2016 , ... Standard Process Inc. ... across the United States. The whole food nutrient solutions company can help veterinarians ... dog, cat and horse owners’ peace of mind. With the increased support, veterinarian ...
(Date:5/5/2016)... ... ... The 2016 Nike Soccer Camp will be directed by the 2015 Big ... they bring their winning Vandals coaching philosophy to young athletes. Programs are offered for ... school players. Session dates are as follows: , Youth Day Camp – July 11th-14th, ...
Breaking Medicine News(10 mins):
(Date:5/5/2016)... 2016  Diagnostic imaging has been on the ... that these tests cause health care costs to spike. However, ... well as the adoption of new guidelines are ... that help health care providers cut costs, while helping patients ... a renowned authorized reseller of the medical industry,s ...
(Date:5/5/2016)... Research and Markets has announced the addition of the  "Market ... to their offering.  ,     (Logo: http://photos.prnewswire.com/prnh/20160330/349511LOGO ) , ... Emission Tomography (PET) scanner and cyclotron install base in the ... France , Germany , ... United Kingdom . Along with the current ...
(Date:5/5/2016)... DUBLIN , May 5, 2016 ... Markets has announced the addition of the  ... Highlights - 2016"  report to their ... http://photos.prnewswire.com/prnh/20160330/349511LOGO ) , ,The latest ... Landscape Highlights - 2016, provides comprehensive ...
Breaking Medicine Technology:
Cached News: