HOME >> MEDICINE >> NEWS
Long-term use of oral contraceptives could increase risk of cervical cancer for women with HPV

Women who are positive for the sexually transmitted human papillomavirus (HPV) could be at a three times greater risk of cervical cancer if they have used oral contraceptives for five years or longer, suggest authors of a study in this weeks issue of THE LANCET. However, there is no evidence that long-term oral-contraceptive use increases the risk of cervical cancer in the absence of HPV.

The absolute risk of cervical cancer ranges from around 1% in developed countries to 5% in less-developed settings. The effect of HPV-the main cause of cervical cancer-has not usually been taken into account in previous studies investigating a possible link between oral-contraceptive use and cervical cancer. Victor Moreno and colleagues from the International Agency for Research on Cancer (IARC) aimed to assess how use of oral contraceptives affected risk of cervical cancer in women who tested positive for HPV DNA.

The investigators pooled data from eight case-control studies of patients with histologically confirmed invasive cervical carcinoma (ICC) and from two studies of patients with carcinoma in situ (ISC [a precursor of ICC]). Information about use of oral contraceptives was obtained from personal interviews. Data were available for around 1900 women from Thailand, the Philippines, Morocco, Brazil, Peru, Paraguay, Colombia, and Spain.

94% of women with ICC, 72% with ISC, and 13% of women without cervical cancer were positive for HPV DNA. Compared with women who had never used oral contraceptives, those who had used oral contraceptives for fewer than 5 years did not have an increased risk of cervical cancer. Women who used oral contraceptives for between five and nine years were around three times more likely to have cervical cancer; there was a four-fold increased risk for oral contraceptive use of 10 years or more.

Silvia Franceschi comments: "We think that our results lend support to the existence of an association between oral contracept
'"/>

Contact: Richard Lane
richard.lane@lancet.com
44-20-7424-4949
Lancet
27-Mar-2002


Page: 1 2

Related medicine news :

1. Long-term high consumption of red and processed meat linked with increased risk for colon cancer
2. Long-term data show benefit of DETROL LA as first-line therapy for overactive bladder
3. Long-term benefits for newly diagnosed patients with CML receiving first-line therapy with imatinib
4. Long-term obesity linked to loss of brain tissue in women
5. Long-term study demonstrated ADDERALL XR is an effective option to treat adolescents with ADHA
6. Long-term study proves ADDERALL XR is a safe and effective option to treat adults with ADHD
7. Long-term use of antibiotics possibly linked with increased risk of breast cancer
8. Long-term follow-up of mortality in patients with community-acquired pneumonia
9. Long-term outcome of epilepsy surgery is favorable for many
10. Long-term ERT in postmenopausal women with Alzheimers may worsen memory
11. Long-term avoidance of milk in children results in poor bone health

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:12/5/2019)... NORWALK, Conn. (PRWEB) , ... December 05, 2019 ... ... — Physician Practice M&A: Risks and Rewards of Building Platforms— on Thursday, December ... organizations are competing for large, multi-specialty medical groups. Middle-market PE firms are scrambling ...
(Date:12/5/2019)... ... 2019 , ... Today at M Health Fairview University of Minnesota ... who will to help them take medicine, relax during anxious moments, encourage them ... presented by NutriSource® is a golden retriever and the first and only full-time ...
(Date:12/4/2019)... ... , ... WEDI , the nation’s leading nonprofit authority on the use ... advisor to the U.S. Department of Health and Human Services (HHS), announced today the ... WEDI Winter Conference in Arlington, Va. on Wednesday, December 4. , “The WEDI Board ...
(Date:12/4/2019)... CHAPEL HILL, N.C. (PRWEB) , ... December 04, 2019 , ... ... and their families easily find their way around the campuses of UNC Medical Center ... navigation inside the two hospitals, parking garages, clinics and more. , The free interactive ...
(Date:12/2/2019)... JERSEY CITY, N.J. (PRWEB) , ... December 02, ... ... transparency and disclosure compliance solutions, has worked with EMD Serono, the North American ... new website, https://clinicaltrials.emdgroup.com . This site is designed to educate and inform ...
Breaking Medicine News(10 mins):
(Date:12/4/2019)... ... December 04, 2019 , ... ... financial, operational and clinical health for our partners, today announced Steve Kiewiet, ... College of Healthcare Executives (ACHE). , ACHE is an international professional society ...
(Date:12/2/2019)... Calif. (PRWEB) , ... December 02, 2019 , ... ... of business support services to dental groups in the United States, today announced ... the community of Tulare, CA. , Patients will enjoy convenient hours, a ...
(Date:11/30/2019)... , ... November 29, 2019 , ... ... cancer screening, that uses deep learning algorithms to automatically detect potential breast cancer ... Radiological Society of North America (RSNA) meeting, December 1-6, 2019 (ScreenPoint Medical, South ...
Breaking Medicine Technology:
Cached News: