HOME >> MEDICINE >> NEWS
Low platelet counts linked to decreased survival in HIV-infected women

SAN DIEGO (Dec. 5, 2004) - HIV-positive women with low blood platelet counts face significantly higher risk of death compared to women with normal counts, according to a study presented today at the 46th Annual Meeting of the American Society of Hematology.

Findings come from the Women's Interagency HIV Study, or WIHS, a prospective study of women living with HIV (as well as HIV-negative women for comparison) in six urban areas across the United States. In this portion of the study, researchers looked at 1,990 HIV-infected women and 553 HIV-negative women.

When entering the study, 15 percent of HIV-positive women and less than 2 percent of the HIV-negative women had low blood platelet counts, also called thrombocytopenia. Platelets are minute cells in the blood that help in the blood clotting process.

The researchers found that women with thrombocytopenia-a platelet count of fewer than 50,000 platelets per cubic millimeter-had a five-fold increase risk of dying due to any cause, compared to women with normal platelet counts. Thrombocytopenia also was linked to a three-fold risk of dying due to AIDS.

"Only a low CD4+ lymphocyte count, one under 200 cells per cubic millimeter, could compare in the strength of its link to mortality," says WIHS principal investigator Alexandra M. Levine, M.D., Distinguished Professor of Medicine, chief of hematology at the Keck School of Medicine of USC and medical director of the USC/Norris Cancer Hospital. Physicians have long relied on counts of CD4+ lymphocyte as a key measure of immunosuppression in HIV-infected patients.

Fortunately, many women saw their platelet counts boosted back to normal through use of highly active antiretroviral therapy, or HAART, especially therapy containing zidovudine, also called AZT.

Researchers found that factors associated with increased risk of thrombocytopenia included HIV infection, low CD4+ lymphocyte counts, increasing viral load, and smoking. Int
'"/>

Contact: Sarah Huoh
shuoh@usc.edu
323-442-2830
University of Southern California
5-Dec-2004


Page: 1 2

Related medicine news :

1. Three anti-platelet drugs used in combination are safe
2. How platelets help cancer invade other tissues
3. Binge drinking: red wine and alcohol have different effects on platelets
4. Antiplatelet drug found to reduce risk of recurrent heart attacks and stroke is cost-effective
5. Antiplatelet drugs: comparison of clopidogrel with aspirin
6. Study shows combining antiplatelet drug Abciximab with clot-buster is effective in treating heart-attack patients
7. Laser method identifies, counts toxic molecules
8. For healthy diet, learning level counts more than earning level
9. USC researchers find ozone lowers sperm counts
10. Hand size counts in safe handgun use
11. Study finds factors linked to substance use disorder relapse among health care professionals

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/20/2017)... ... June 20, 2017 , ... Hayes, Inc., a leading ... eBook titled “ 5 Questions to Ask Before Entering the Maze of Genetic ... Test Evaluation (GTE) team, the book explores the various types of the more ...
(Date:6/20/2017)... , ... June 20, 2017 , ... ... contending that the introduction of school choice can promote economic development in economically ... school that has, according to the report, contributed to the economic development of ...
(Date:6/20/2017)... ... June 20, 2017 , ... MindTouch , the ... is proud to announce Touchpoints integrations. MindTouch Touchpoints easily integrate product ... more to provide a seamless customer experience. , Truly “plug and play,” Touchpoints ...
(Date:6/20/2017)... , ... June 20, 2017 , ... As a leading ... the link between stroke and gum disease. Those with bleeding gums in Vancouver, BC, ... untreated, this condition can lead to heart disease, stroke and diabetes. Drs. Parviz Roshan, ...
(Date:6/20/2017)... Boston, MA (PRWEB) , ... June 20, 2017 ... ... Innovation’s (IPI) Clinical Innovation Catalyst program focused on finding product improvements ... have tubes placed in their throats when they need help breathing or to ...
Breaking Medicine News(10 mins):
(Date:6/12/2017)... June 12, 2017 Kineta, Inc., a biotechnology company ... Kineta Vice President of R&D and Head of Virology ... Pandemic Preparedness for the Northwest and Beyond meeting sponsored ... June 14, 2017 from 8:30-10:30 AM PDT at the Agora ... Dr. Bedard will be joined by other leaders ...
(Date:6/8/2017)... June 8, 2017  Less than a month ago, ... than 200,000 companies, including hospital networks, in over 150 ... one of the largest online extortion attempts ever recorded. ... market, it is imperative that providers understand where the ... from this — and many other very real cyber ...
(Date:6/7/2017)... URBANDALE, Iowa , June 6, 2017  Diplomat Specialty Infusion ... a sterile compounding environment to its Iowa ... Urbandale now features an ISO 7 cleanroom—the ... a controlled environment with a low level of pollutants. ... serve more IV nutrition consumers and better serve our ...
Breaking Medicine Technology:
Cached News: