Loyola study shows drug-coated stent induces less inflammation than bare metal stent

NEW ORLEANS - In the treatment of coronary artery disease, a sirolimus drug-coated stent causes less inflammation than bare metal stents, according to preliminary research presented at the American Heart Association annual meeting by Loyola University Health System, Maywood, Ill.

"Inflammatory response is a sign of advancing heart disease, so the less inflammation the better," said lead author Dr. Fred Leya, professor of medicine/cardiology, Loyola University Chicago Stritch School of Medicine. Stents are small stainless steel coils or scaffolds which are used to keep blood vessels open and maintain blood flow to the heart. The drug-coated stent reduces the risk of restenosis (renarrowing) of blood vessels after angioplasty, a common problem with earlier stents, where 30 percent of arteries renarrowed.

"Many times with the earlier stents, tissue cells grew too much scar tissue, renarrowing the artery that the stent was supposed to widen," said Leya, director, interventional cardiology and director, cardiac catherization lab at Loyola.

Leya said that the FDA-approved stent produces immediate results. "It is especially appropriate for diabetics, because they have smaller arteries and thus a greater risk of restenosis of coronary vessels following angioplasty," he said.

Participating in the inflammation study were 55 patients: 27 received the drug-coated stent; another 28 patients were treated with a bare-metal stent. Researchers, looking for inflammation markers, took blood samples at baseline, and at 12- to 24 hours and four- to six hours after the procedure.

Results of the study shows that inflammatory response was substantially reduced among patients who received the drug eluting stent compared to the bare metal stent.

The next step, Leya said, is to measure inflammatory markers at one-year. The stent uses a polymer, which acts as a time-release mechanism over approximately 30-45 days, t

Contact: Joanne Swanson
Loyola University Health System

Page: 1 2

Related medicine news :

1. Loyola warns lower temps mean greater risk of fire from space heaters
2. First head-to-head study to compare lidoderm patch and Celebrex in treating pain
3. UMaine study looks at infants and chronic nighttime crying
4. Chronic pain treatments more effective when taken together, new study shows
5. UNC study: Most N.C. family practitioners engage in unrecognized community service
6. New study in Nature demonstrates protection against cell death during heart attack
7. UCSF study offers insight into human circadian rhythms
8. International breast cancer prevention study launches in the United States and Canada
9. UW study shows blacks and Latinos are more satisfied with physicians of the same race
10. Physicians may not be accurate in their confidence levels of their diagnoses, says Pitt study
11. Advertising by academic medical centers may risk eroding public trust, says study

Post Your Comments:

(Date:10/13/2017)... ... October 13, 2017 , ... PurhealthRX , a leading ... Purzorb™ technology. Applying the Purzorb™process to full spectrum CBD oil will revolutionize the rapidly ... CBD form that can be easily incorporated into liquid products, while reducing costs to ...
(Date:10/13/2017)... BASKING RIDGE, N.J. (PRWEB) , ... October 13, 2017 , ... ... second annual Holly Day Market. Featuring a collection of specialty vendors and unique items ... myriad of personalized and quality-focused health and wellness services offered by the VNA. ...
(Date:10/13/2017)... (PRWEB) , ... October 13, 2017 , ... ... DevOps and Agile Software Development, has been awarded a contract by the Center ... Purchase Agreement (BPA) aims to accelerate the enterprise use of Agile methodologies in ...
(Date:10/12/2017)... ... 12, 2017 , ... Planet Fitness, one of the largest and fastest growing ... open a flagship location in Covington, LA at 401 N. U.S. Highway 190, in ... to Office Depot in the Holiday Square shopping center. Its location allows it to ...
(Date:10/12/2017)... ... October 12, 2017 , ... Information about the technology: ... develop to enable prevention of a major side effect of chemotherapy in children. ... pediatric patients. For cisplatin, hearing loss is FDA listed on-label as a dose ...
Breaking Medicine News(10 mins):
(Date:10/11/2017)... IRVING, Texas , Oct. 11, 2017  Caris ... science focused on fulfilling the promise of precision medicine, ... Institute has joined Caris, Precision Oncology Alliance™ (POA) as ... leading cancer centers, the St. Jude Crosson Cancer Institute ... to advance the use of tumor profiling, making cancer ...
(Date:10/7/2017)... 6, 2017   Provista, a proven leader ... billion in purchasing power, today announced a new resource ... The Newsroom is the online home for case ... expert bios, news releases, slideshows and events. ... wealth of resources at their fingertips, viewers can also ...
(Date:10/2/2017)... Mich. , Oct. 2, 2017 Diplomat ... 8th Day Software and Consulting, LLC , and ... 8th Day Software, based in Tennessee ... LLC. 8th Day expands EnvoyHealth,s service offerings for health ... development. "In an ...
Breaking Medicine Technology:
Cached News: