MGH study details brain changes in autism, language disorder

Using advanced imaging technology, a research team based at Massachusetts General Hospital (MGH) has identified specific portions of the brain's white matter that are abnormally large in children with autism and developmental language disorder (DLD). The findings confirm that the previously observed overgrowth of white matter occurs after birth and suggest that it may be related to the process of myelination, in which portions of nerve cells called axons are covered with a material called myelin. The report appears in the April issue of Annals of Neurology.

The researchers noted that the factor most closely associated with the areas showing the greatest volume increase is when the axons in those areas myelinate, a key step in maturation that allows nerve impulses to be transmitted properly. In both autistic and DLD patients, the most enlarged areas were those that myelinate latest in normal development and where myelination takes a longer period of time.

"Knowing that white matter is most enlarged in the area that develops myelin latest will help us narrow the time window in which to look for the cause of these problems and should help focus future research," says Martha Herbert, MD, PhD, of MGH Neurology and the Center for Morphometric Analysis, the paper's lead author.

Autism is a serious developmental disorder characterized by a lack of normal social interaction, language abnormalities and repetitive, ritualistic behavior. Many earlier studies have shown that autistic children often have unusually large brains and experience rapid brain growth in the first years of life. This increased brain volume appears to be concentrated in the white matter. Primarily made up of axons long processes that extend out from brain or other nerve cells the white matter is located in the interior of the brain, beneath the cerebral cortex which contains the bodies of brain cells.

The same white matter abnormality is found in

Contact: Julie Bergan
Massachusetts General Hospital

Page: 1 2

Related medicine news :

1. First head-to-head study to compare lidoderm patch and Celebrex in treating pain
2. UMaine study looks at infants and chronic nighttime crying
3. Chronic pain treatments more effective when taken together, new study shows
4. UNC study: Most N.C. family practitioners engage in unrecognized community service
5. New study in Nature demonstrates protection against cell death during heart attack
6. UCSF study offers insight into human circadian rhythms
7. International breast cancer prevention study launches in the United States and Canada
8. UW study shows blacks and Latinos are more satisfied with physicians of the same race
9. Physicians may not be accurate in their confidence levels of their diagnoses, says Pitt study
10. Advertising by academic medical centers may risk eroding public trust, says study
11. Fat may promote inflammation, new study suggests

Post Your Comments:

(Date:3/30/2021)... , ... March 29, 2021 , ... ... the 21st Century , A Virtual Workshop Presented by WCG FDAnews and Cerulean ... 4:30 pm EDT, https://wcg.swoogo.com/modern-sop-and-quality-systems , Are one’s SOPs written for the ...
(Date:3/30/2021)... ... March 29, 2021 , ... According to data released ... reproductive age (13-44) in need of publicly funded contraception live in counties impacted by ... Colorado’s 64 counties have lost some of their Title X resources. , The ...
(Date:3/30/2021)... ... March 29, 2021 , ... Health Literacy Innovations (HLI), a ... confusion due to low health literacy today announces a new partnership with the ... work with ACAP’s member Safety Net Health Plans, those that provide comprehensive health ...
(Date:3/30/2021)... ... ... Dr. Colin Campbell is proud to announce the 1 year anniversary in their new state ... internal medicine and is a primary care specialist who has been practicing for 23 years. ... keep South Jersey healthy one patient at a time. , “Over the past year, Dr. ...
(Date:3/30/2021)... ... March 30, 2021 , ... The COVID-19 ... and survivors; their families; and their caregivers. Crossroads4Hope is addressing the needs of ... emotional support system, MyGo2Support, which meets needs of people impacted by cancer, no ...
Breaking Medicine News(10 mins):
(Date:3/30/2021)... ... March 29, 2021 , ... The University of Texas Health Science Center ... San Antonio Multispecialty and Research Hospital, a destination center for research and treatment of ... In a nod to the COVID-19 pandemic, the ceremony was held virtually. , William ...
(Date:3/30/2021)... ... March 29, 2021 , ... Iora Health ... primary care, has partnered with Devoted Health , one of the fastest-growing ... across Maricopa County and provides seniors with the highest-quality care and experience possible, ...
(Date:3/30/2021)... CITY (PRWEB) , ... March 29, 2021 , ... ... has joined the Vaccine Credential Initiative (VCI), a group bringing together leading health ... record of vaccination status, based on open, interoperable standards. By joining the VCI ...
Breaking Medicine Technology:
Cached News: