HOME >> MEDICINE >> NEWS
MRI can measure early benefits of cholesterol-lowering drugs and plaque reduction

Using modified magnetic resonance imaging (MRI) techniques, researchers at Johns Hopkins have been able to detect the early benefits of a cholesterol-lowering medication much sooner than before.

The researchers applied MRI to measure the success of simvastatin (Zocor), a widely used form of so-called statin therapy, in reducing plaque formation in patients with hardened and clogged arteries, or atherosclerosis. Reductions in plaque levels were detected within six months after therapy began. Traditionally, MRI has been unable to show results until one or two years after the onset of treatment.

The Hopkins findings, to be published in the journal Circulation online Oct. 11, should make it easier for physicians to monitor how well initial cholesterol-lowering therapy works for patients, especially those with advanced-stage cardiovascular disease in need of quick results.

The research also linked the early benefits of statins to their lipid-lowering actions, not to anti-inflammatory properties as some earlier studies suggested.

"Our study increases the likelihood that MRI could eventually be used as a predictive technology for determining which patients should be placed on statin therapy for atherosclerosis," said the study's lead author and cardiologist Joo Lima, M.D., associate professor of medicine and radiology at The Johns Hopkins University School of Medicine.

"Heart disease, especially atherosclerosis, is still the leading cause of death in the United States," added Lima. "While it has been proven that patients can benefit from even a short period of statin therapy, as early as 16 weeks, our abilities to harness modern technology for monitoring this condition - and tracking the effectiveness of our treatments - have not kept pace until now."

Cholesterol-lowering medications, which decrease lipid/fat levels in the blood, have been shown to reduce plaque formation by as much 30 percent to 40 percen
'"/>

Contact: David March
dmarch1@jhmi.edu
410-955-1534
Johns Hopkins Medical Institutions
11-Oct-2004


Page: 1 2 3

Related medicine news :

1. University of Manchester makes made-to-measure skin and bones a reality using inkjet printers
2. Size of myocardial infarct measured using MRI
3. Study finds women hesitant to take tamoxifen as preventive measure
4. How are we doing? Researchers aim to measure national well being
5. Study finds computer vignette to be effective way to measure quality of physician practice
6. Health state values for patients with CAD vary according to the measure used to generate them
7. Tar measurements on cigarette packets are misleading
8. Antioxidant controversy: Scientists seek measurement standards
9. Study measures risks of exclusive pipe smoking
10. UCSF/Baylor team uses new method to measure bone loss in astronauts flying long mission
11. Metabolic footprint may be new measure of obesity risk in kids

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/26/2016)... Aliso Viejo, California (PRWEB) , ... June 26, 2016 , ... ... for Final Cut Pro X. , "Film editors can give their videos a whole ... artistically," said Christina Austin - CEO of Pixel Film Studios. , ProSlice Levels ...
(Date:6/25/2016)... ... 2016 , ... Experts from the American Institutes for Research ... June 26-28, 2016, at the Hynes Convention Center in Boston. , AIR experts ... planning, healthcare costs and patient and family engagement. , AIR researchers will be ...
(Date:6/25/2016)... ... , ... First Choice Emergency Room , the largest network of independent ... Director of its new Mesquite-Samuell Farm facility. , “We are pleased to announce ... Dr. James M. Muzzarelli, Executive Medical Director of First Choice Emergency Room. , ...
(Date:6/25/2016)... ... June 25, 2016 , ... Conventional wisdom preaches the benefits of ... of the latter, setting the bar too high can result in disappointment, perhaps even ... progress toward their goal. , Research from PsychTests.com reveals that behind ...
(Date:6/24/2016)... ... June 24, 2016 , ... Marcy was in a crisis. Her son James, eight, was out ... family verbally and physically. , “When something upset him, he couldn’t control his emotions,” remembers ... would throw rocks at my other children and say he was going to kill them. ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... -- Research and Markets has announced the addition ... to their offering. The ... commercial environment for MedImmune to enter. The US ageing population ... to drive considerable growth for effective anti-influenza medications. The introduction ... considerably, but development is still in its infancy. ...
(Date:6/23/2016)... , June 23, 2016  Astellas today announced the establishment of Astellas Farma Colombia (AFC), a new affiliate with ... Latin America . ... ... ... ...
(Date:6/23/2016)... -- Research and Markets has announced the ... (United States, China, Japan, Brazil, United Kingdom, Germany, France, ... Surgical Procedure Volumes: ... provides surgical procedure volume data in a geographic context. ... analysis of growth drivers and inhibitors, including world population ...
Breaking Medicine Technology:
Cached News: