HOME >> MEDICINE >> NEWS
Magnesium sulfate to mothers just prior to delivery of preterm babies may improve outcomes

Women who are given intravenous magnesium sulfate just before the birth of a very preterm baby may reduce the infant's risk of neurosensory impairments such as cerebral palsy, though this finding needs to be confirmed in other studies before it becomes standard practice, according to an article in the November 26 issue of The Journal of the American Medical Association (JAMA).

Infants born very preterm have increased risks of death or neurosensory impairments and disabilities such as cerebral palsy, according to background information in the article. Although other studies have suggested that use of prenatal magnesium sulfate may act as a neuroprotective agent for very preterm infants, there have been no large randomized controlled trials in which magnesium sulfate was given solely for neuroprotection.

Caroline A. Crowther, M.D., of The University of Adelaide, South Australia, and colleagues conducted a study to determine the effectiveness of magnesium sulfate in preventing pediatric death and/or cerebral palsy when given to women at risk of delivery before 30 weeks' gestation.

The study was a randomized controlled trial at 16 hospitals in Australia and New Zealand. It included 1,062 women with fetuses younger than 30 weeks' gestation for whom delivery was planned or expected within 24 hours. The participants were enrolled from February 1996 to September 2000 with follow-up of surviving children at 2 years of age. Women were randomly assigned to receive an intravenous infusion of magnesium sulfate solution or sodium chloride solution (as placebo) for 20 minutes followed by a maintenance infusion for up to 24 hours.

Data were analyzed for 1,047 (99 percent) 2-year survivors. "Total pediatric mortality (13.8 percent vs. 17.1 percent; [17 percent reduced risk]), cerebral palsy in survivors (6.8 percent vs. 8.2 percent; [17 percent reduced risk]), and combined death or cerebral palsy (19.8 percent vs. 24.0 percent; [17 percent reduc
'"/>


25-Nov-2003


Page: 1 2

Related medicine news :

1. Magnesium sulphate halves risk of eclampsia for pregnant women with pre-eclampsia
2. Single mothers at higher risk for depression
3. Nursing mothers having surgery -- How long a wait to breastfeed safely?
4. Study finds no reason for expectant mothers to shy away from early epidurals
5. Health issues may affect grandmothers who are primary caregivers
6. Pediatricians can help immigrant mothers by explaining child development, NICHD study suggests
7. Improving health for mothers and children in South Asia
8. Laws designed to prevent too-short hospital stays allow mothers more time, study shows
9. Emory and CDC scientists explore why most breastfed infants of HIV-positive mothers resist infection
10. First study to show link between childrens solid tumours and their mothers breast cancer
11. Robo-thespians help mothers of kids with cancer

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:2/19/2019)... , ... February 19, 2019 , ... ... communication services, launched their newest release of their enrollment kit solution, called ONEkit™ ... enrollment materials for their new and existing customers. ONEkit is integrated with O’Neil’s ...
(Date:2/19/2019)... ... February 19, 2019 , ... ... center in the United States and a part of the Prelude Fertility ... the campus of Piedmont Atlanta Hospital. , The only reproductive endocrinology practice on ...
(Date:2/19/2019)... ... 2019 , ... K.J. Kidd, a Missouri native born and raised along the ... autobiographical work offered to encourage other women to be proactive about their bone health ... September 28th of 2013, I spent my entire morning walking up and down Clearwater ...
(Date:2/19/2019)... ... 19, 2019 , ... The San Diego Superior Court has entered a judgment ... on behalf of a class of approximately 14,100 patients who were admitted in-patient to ... June 30, 2013, in a class action case (Santana, et al. v. Rady Children’s ...
(Date:2/16/2019)... ... February 15, 2019 , ... ... of its newest accreditation program, which will bring the benefits of national accreditation ... health departments. The new Vital Records and Health Statistics Accreditation Program ...
Breaking Medicine News(10 mins):
(Date:2/16/2019)... ... February 15, 2019 , ... Adolfson & ... (MNSHARP) award for safety excellence. Commissioner Kristin Batson, Department of Labor and Industry ... Safety is more than just a set of rules for AP; it’s our ...
(Date:2/16/2019)... ... February 15, 2019 , ... State-of-the-art aesthetic and wellness ... in urology, COR Medspa is committed to helping patients realize their best with ... COR stands for Center Of Rejuvenation, and is on a mission to provide ...
(Date:2/14/2019)... ... February 14, 2019 , ... ... focuses on developing and commercializing minimally-invasive, innovative spinal technologies, today announced a ... Surgical name better emphasizes our commitment to delivering new, cutting-edge, surgical solutions ...
Breaking Medicine Technology:
Cached News: