HOME >> MEDICINE >> NEWS
Mailman School of Public Health researchers develop infectious disease diagnostic tool

February 7, 2005 - Researchers at Columbia University's Mailman School of Public Health and the Columbia Genome Center have designed and developed a sensitive new diagnostic technology platform, called "Mass Tag PCR," that can simultaneously screen for multiple infectious agents. The new technology is addressed in a paper published in the February issue of the Centers for Disease Control and Prevention's (CDC) Emerging Infectious Diseases. This new platform is demonstrated in an assay that detects and discriminates 22 pathogens including viruses and bacteria that can present as clinically similar pulmonary disease.

This new technology platform addresses important challenges for infectious disease identification-sensitivity and breadth. Mass Tag PCR provides the ability to be precise in identification, as well as the ability to apply current diagnostics to more than one pathogen at a time, thereby reducing the time needed for differential diagnosis.

"We focused first on respiratory diseases because differential diagnosis is a common clinical problem with implications for outbreak control and individual case management," stated W. Ian Lipkin, MD, Jerome L. and Dawn Greene Professor of Epidemiology and professor of Neurology and Pathology at Columbia University, and senior author of the paper. "However, we envision implementing this method for a wide variety of applications such as blood product surveillance, agriculture, forensic microbiology, and biodefense."

To address the need for highly sensitive diagnostics, researchers built on an established method known as polymerase chain reaction that allows amplification of genetic sequences and on a technology previously used for DNA sequencing and detection of genetic polymorphisms. Genetic probes for pathogens were coupled to markers known as mass codes. After amplification, incorporated mass codes were detected by mass spectroscopy allowing identification of the pathogen.

Accor
'"/>

Contact: Stephanie Berger
sb2247@columbia.edu
212-305-4372
Columbia University's Mailman School of Public Health
7-Feb-2005


Page: 1 2

Related medicine news :

1. Mailman School of Public Health receives Manhattan Tobacco Cessation Center grant
2. Philanthropist Paul F. Glenn launches labs for aging research at Harvard Medical School
3. School-based smoking prevention programs ineffective
4. Dartmouth Medical School receives $1.6 million in AIDS funding
5. Three-year health study of teenage girls is underway at Trenton Central High School
6. IU Medical School poised to host global HIV/AIDS conference
7. High fiber intake reduces estrogen levels in Latina women, say Keck School of Medicine researchers
8. Research news from the Friedman School of Nutrition Science and Policy at Tufts University
9. $25 million funds health promotion studies at UT School of Public Health
10. University of Maryland School of Medicine scientist receives prestigious presidential award
11. Friedman School of Tufts: Policy Points

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:7/17/2019)... IRVINE, Calif. (PRWEB) , ... July 17, 2019 ... ... of enterprise-wide solutions to health plans participating in Medicare Advantage, Medicaid, and Marketplace ... solution for Providers featuring Electronic Health Records (EHR) integration at ...
(Date:7/17/2019)... ... July 17, 2019 , ... This past Saturday, Monarch Dental® ... Everyone Foundation . Over 50 underserved patients were welcomed at the Mesquite office to ... celebrating the summer season. Individuals were referred to the event through local nonprofit organizations ...
(Date:7/17/2019)... Mich. (PRWEB) , ... July 17, 2019 , ... Women’s Excellence is pleased to announce ... this summer in September. The new offices resides on the corner of Turrill Road ... listened! We are thrilled about the opening of our new office in Lapeer and ...
(Date:7/13/2019)... ... July 12, 2019 , ... ... of its proprietary patient management platform, Ospitek “View”. Ospitek has partnered with some ... deliver a fully customizable, intelligent, solution made specifically for surgical centers, allowing them ...
(Date:7/12/2019)... PLAINS, N.J. (PRWEB) , ... July 12, 2019 , ... ... reviewed and approved by NJ Top Docs for 2019. Located in Paramus, BAXT CosMedical ... been providing state-of-the-art cosmetic and medical dermatological care for the past 45 years. , ...
Breaking Medicine News(10 mins):
(Date:7/17/2019)... ... ... Chlorophyll Water was selected by the Permanent Mission of India to be the ... International Day of Yoga, unofficially referred to as Yoga Day, is celebrated annually on ... General Assembly. , Marking the International Yoga Day, the United Nations held a series ...
(Date:7/17/2019)... ... July 17, 2019 , ... Halcyon, ... American as its payment processor of record. , As a result of ... business management platform can now also accept and process payments through it, securely ...
(Date:7/17/2019)... , ... July 17, 2019 , ... Trusted dentist, ... their smiles with Kanani's innovated bonding procedures. Bonding is just one of the many ... can be done in a single visit, and patients leave immediately happy with their ...
Breaking Medicine Technology:
Cached News: