Major advance in chemotherapy in breast cancer

San Antonio, TX December 5, 2003 A Docetaxel (Taxotere)-based regimen reduced the relative risk of death in women with early stage breast cancer by 30 percent and lowered the relative risk of the cancer returning by 28 percent when compared to a standard adjuvant (post-surgery) regimen after 55-month follow-up. The results of BCIRG 001, the first phase III study evaluating Taxotere after breast surgery, were presented at the San Antonio Breast Cancer Symposium (SABCS) by the Breast Cancer International Research Group (BCIRG) today.

"Taxotere continues to demonstrate its effectiveness across various stages of breast cancer, and this study indicates that women with early stage breast cancer and their physicians should seriously consider a Taxotere-based treatment, like the TAC regimen tested in the BCIRG 001 trial, to significantly prolong disease-free survival and survival," said Miguel Martin M.D. from the Medical Oncology Department, Hospital Universitario San Carlos, Madrid, Spain, chairman of GEICAM.

Study Design
The BCIRG 001 study was designed to determine if Taxotere, one of the most active agents in advanced breast cancer, would also have benefits for women with early stage disease. Study participants received either a post-surgery regimen of Taxotere, doxorubicin (Adriamycin), and cyclophosphamide (Cytoxan), known as TAC, or the widely used standard regimen of 5-fluorouracil, doxorubicin and cyclophosphamide, known as FAC. BCIRG 001 enrolled 1,491 pre- and post-menopausal women with early breast cancer at 111 sites in 20 countries; 745 patients were randomized to receive TAC and 746 to receive FAC. The study was designed to perform analyses on subgroups of women based on hormonal receptor status (hormone-receptor-positive or hormone-receptor-negative tumors) and nodal involvement (one-to-three or four-plus axillary lymph nodes). Tumor samples were prospectively collected for 95 percent of the patients. Hormonal receptor s

Contact: Arleen Goldenberg
Cohn & Wolfe

Page: 1 2 3 4

Related medicine news :

1. Major review of subway systems suggests potential for significant health and safety hazards
2. Major step forwards for vaccine against cervical cancer
3. Majority of cigarettes in the US smoked by nicotine-dependent or psychiatrically ill persons
4. Major overhaul needed in end-of life care for patients with dementia
5. Major overhaul needed in end-of life care for patients with dementia
6. Major radiology journal offers unrestricted access to recently archived articles
7. Major study: Bioartificial liver reduces mortality by 44 percent in acute liver-failure patients
8. Majority of authors retract 1998 Lancet paper-Lancet editor points to implications
9. Major agreement reached at heart health conference
10. Major risk factors identified for sudden infant death syndrome
11. Major cause of painful gastroenteritis under study at MCG

Post Your Comments:

(Date:1/23/2020)... (PRWEB) , ... January 23, 2020 , ... ... IRF Executive Committee and the IRF Board of Trustees. Representing all segments of ... foundation in meeting its mission of conducting research and providing education highlighting the ...
(Date:1/23/2020)... ... January 23, 2020 , ... NowRx , the ... Orange County today with the grand opening of its state-of-the-art, 4,500 square foot, ... time of a traditional pharmacy. NowRx uses an eco-friendly fleet of delivery ...
(Date:1/22/2020)... (PRWEB) , ... January 22, ... ... that provides hearing, speech, and education services, recently appointed Ilana Glazer as ... communications, and outreach initiatives. Specifically, Ilana directs donor relations, grants administration, external ...
(Date:1/22/2020)... ... January 22, 2020 , ... Dr. Mario ... band can be for reducing food intake, enabling sustainable weight loss and improving ... while bariatric surgery may be a great tool for achieving significant weight loss, ...
(Date:1/12/2020)... ... January 11, 2020 , ... The co-founder and CEO of ... with the annual JP Morgan Healthcare Conference. On Sunday, January 12, Sujuan Ba, ... technology company investors and advisers at the San Francisco office of international law ...
Breaking Medicine News(10 mins):
(Date:1/24/2020)... ... January 24, 2020 , ... The American College of ... a systematic reform of the health care system. Recently, practicing internist and President of ... of Governmental Affairs and Public Policy at ACP, teamed with YourUpdateTV to discuss how ...
(Date:1/23/2020)... ... January 23, 2020 , ... ... assisted living community, has received a deficiency-free survey in 2019 as administered ... receive a deficiency-free survey from the State,” said Glen Cummins Regional Director of ...
(Date:1/23/2020)... ... January 23, 2020 , ... As Sarasota’s older population surges, ... want to stay in their own homes, according to The American Association of Retired ... care . Now, affluent seniors seeking truly professional caregivers have a new option -- ...
Breaking Medicine Technology:
Cached News: