HOME >> MEDICINE >> NEWS
Major new study finds long-acting calcium channel blockers inferior to other antihypertensive drugs

Up to 85,000 unnecessary heart attacks and cases of heart failure may occur worldwide every year among the estimated 28 million users of longer-acting calcium channel blockers (CCBs), a class of drugs used to treat high blood pressure, according to the results of a study reported today at the European Society of Cardiology meeting in Amsterdam.

The combined analysis of nine randomized clinical trials, with a total of more than 27,000 patients, showed that the longer-acting CCBs are inferior to other proven and less expensive drugs in preventing the cardiovascular complications of hypertension.

The study was conducted at Wake Forest University School of Medicine in Winston-Salem, the University of Washington-Seattle, and Albert Einstein College of Medicine, Bronx, New York.

"The results are remarkably consistent across the trials," said Marco Pahor, M.D., professor of internal medicine at Wake Forest and the study's lead researcher. "In the CCB-treated patients, the risk of a heart attack was 27 percent higher, the risk of heart failure was 26 percent higher and the risk of any major cardiovascular event was 11 percent higher. There was no difference in stroke or total mortality; and there was no evidence of differences among the CCBs tested."

The results add to a growing body of evidence that antihypertensive drugs, despite having equal effect on blood pressure, may vary in their ability to prevent heart attacks and congestive heart failure, said Curt D. Furberg, M.D., Ph.D., professor of public health sciences at Wake Forest University School of Medicine and a co-researcher of the study.

"The overuse of these less effective CCBs -- which can cost 10 to 15 times more than diuretics -- is a major avoidable clinical problem that requires immediate attention," Furberg told the cardiology society meeting in Amsterdam. The study examined the results of nine long-term trials involving 27,743 patients, with a total of about 120,000 person-years
'"/>

Contact: Karen Richardson
krchrdsn@wfubmc.edu
336-716-4587
Wake Forest University Baptist Medical Center
28-Aug-2000


Page: 1 2 3

Related medicine news :

1. Major review of subway systems suggests potential for significant health and safety hazards
2. Major step forwards for vaccine against cervical cancer
3. Majority of cigarettes in the US smoked by nicotine-dependent or psychiatrically ill persons
4. Major overhaul needed in end-of life care for patients with dementia
5. Major overhaul needed in end-of life care for patients with dementia
6. Major radiology journal offers unrestricted access to recently archived articles
7. Major study: Bioartificial liver reduces mortality by 44 percent in acute liver-failure patients
8. Majority of authors retract 1998 Lancet paper-Lancet editor points to implications
9. Major agreement reached at heart health conference
10. Major risk factors identified for sudden infant death syndrome
11. Major cause of painful gastroenteritis under study at MCG

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/13/2017)... ... October 13, 2017 , ... Global Healthcare Management’s 4th Annual Kids Fun ... NJ. This free event, sponsored by Global Healthcare Management’s CEO, Jon Letko, is ... is geared towards children of all ages; it is a non-competitive, non-timed event, which ...
(Date:10/13/2017)... ... ... On The Brink”: the Christian history of the United States and the loss of ... William Nowers. Captain Nowers and his wife, Millie, have six children, ten grandchildren, ... Navy. Following his career as a naval aviator and carrier pilot, he spent ...
(Date:10/12/2017)... PALM CITY, Fla. (PRWEB) , ... October 12, 2017 , ... ... of cold therapy products, announced today the introduction of an innovative new design of ... the multipurpose pad so you get maximum comfort while controlling your pain while using ...
(Date:10/12/2017)... ... October 12, 2017 , ... HMP , a leader in healthcare events ... Magazine Eddie Digital Award for ‘Best B-to-B Healthcare Website.’ Winners were announced during the ... The annual award competition recognizes editorial and design excellence across a range of sectors. ...
(Date:10/12/2017)... ... October 12, 2017 , ... In the United ... year. In some states—like New York, New Jersey, Massachusetts, Texas, Virginia, Connecticut, and ... havens have extremely low property-tax rates, which contributes to the relatively lower cost ...
Breaking Medicine News(10 mins):
(Date:10/12/2017)... , Oct. 12, 2017   Divoti USA ... Jewelry up to the standard of the latest FDA requirements, which ... 2017). Anyone in need of Medical ID jewelry such ... Alert Jewelry are engraved in terms of the new ... Divoti offers ...
(Date:10/11/2017)... Oct. 11, 2017  True Health, a leader ... its effort during National Breast Cancer Awareness month ... risks. Research ... calculated that more than 10 million American women ... in BRCA1 or BRCA2 and have not had testing. ...
(Date:10/7/2017)... 6, 2017   Provista, a proven leader ... billion in purchasing power, today announced a new resource ... The Newsroom is the online home for case ... expert bios, news releases, slideshows and events. ... wealth of resources at their fingertips, viewers can also ...
Breaking Medicine Technology:
Cached News: