HOME >> MEDICINE >> NEWS
Margin Width The Key To Control Of Ductal Carcinoma In Situ Of The Breast

USC New England Journal Of Medicine Study Urges Caution In Use Of Radiation Therapy

LOS ANGELES, May 5, 1999 - Patients with one of the most common and curable forms of breast cancer may be undergoing radiation therapy unnecessarily, according to a University of Southern California study to be published in the May 13 New England Journal of Medicine.

The study, headed by Melvin J. Silverstein, M.D., medical director of the Harold E. and Henrietta C. Lee Breast Center at the USC/Norris Comprehensive Cancer Center, examines ductal carcinoma in situ (DCIS), a noninvasive breast cancer that has been the subject of a recent heated debate over treatment. Until 1980, DCIS was a relatively uncommon disease, representing only about 1 percent of all newly diagnosed cases of breast cancer. During the past two decades - as mammography has become more widely used and technically better - the number of new cases has increased dramatically.

Today DCIS represents as much as 40 percent of new breast cancer cases diagnosed by mammography, and estimates suggest that approximately 40,000 new cases of DCIS will be diagnosed this year in the U.S. Seventy to 80 percent of these patients are eligible for breast preserving lumpectomy rather than mastectomy. But opinion is currently divided on whether radiation therapy is necessary for all DCIS patients who choose lumpectomy.

In the NEJM article, Silverstein, a surgical oncologist, and colleagues found that radiation therapy does not appear to benefit patients where the margin width - the distance between the boundary of the lesion and the edge of the excised specimen - is 10 millimeters or more.

"Wide margin width makes complete excision more likely," says Silverstein. "Since DCIS is a noninvasive cancer that does not spread (metastasize), complete excision should cure the patient. These findings will have important ramifications for thousands of women with the disease. These data suggest that radi
'"/>

Contact: Mary Ellen Stumpl or Brenda Maceo
maceo@hsc.usc.edu
323-442-2830
University of Southern California
13-May-1999


Page: 1 2 3 4

Related medicine news :

1. Hopkins Institute for Global Tobacco Control receives elite recognition from PAHO/WHO
2. Controlling hormones could reduce risk of strokes in younger people
3. Controlling pain with your brain
4. Five more African countries to benefit from Schistosomiasis Control Initiative
5. Controlled study after Dutch caf fire highlights teen mental-health problems after disasters
6. Control valve within heart cells could protect body during heart attacks
7. Grant of 20 million to establish the Schistosomiasis Control Initiative
8. Controlled crying reduces infant sleep problems
9. Controlling blood pressure early prevents heart disease in elderly
10. AAPS Workshop to Examine Chemistry and Manufacturing Controls Trials, Emerging Products
11. Revolutionary New Procedure That Creates Controlled Heart Attack Performed For First Time In Southern California At Cedars-Sinai Medical Center

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:1/20/2017)... ... 20, 2017 , ... Vitamin Well has launched two new ... have been produced in collaboration with Zlatan Ibrahimovic and have been developed to ... a successful launch in Sweden last year, the next generation sports drinks VW+001 ...
(Date:1/20/2017)... , ... January 20, 2017 , ... “The Angel”: ... Lord has set out for each of his children. “The Angel” is the creation ... of Music in New York City, and impassioned writer. , When asked of her ...
(Date:1/20/2017)... ... January 20, 2017 , ... “I Forgive You”: a fine examination of how ... You” is the creation of published author, Stephen Miller, who, for over ten long years ... given to him. Born in Trinidad and Tobago, he has been serving the Lord for ...
(Date:1/20/2017)... ... January 20, 2017 , ... “Christmas in Suffolk”: a story of love, ... who lives in Lafayette, Indiana where she works in a daycare and looks for ... , Published by Christian Faith Publishing, Sara Seymour’s new book is an adventure of ...
(Date:1/20/2017)... ... January 20, 2017 , ... “Knowledge is God’s Lighthouse”: a ... “Knowledge is God’s Lighthouse” is the creation of published author, Gene Gaapf, a retired ... collections. , “I have been writing since high school and have many different ...
Breaking Medicine News(10 mins):
(Date:1/20/2017)... 2017 Research and Markets has announced ... Opportunities, and Future" report to their offering. ... This research service on the ... technologies, and provides a snapshot of the key participants in the ... are provided from 2016 to 2020. The market is expected to ...
(Date:1/20/2017)... 2017 Avillion LLP, a co-developer and financier ... Weinberg , MD MBA as Chief Medical Officer. Dr Weinberg will ... . ... Weinberg has spent more than 17 years as a pharmaceutical and ... micro-cap biotech. Over the course of his career, he has interfaced ...
(Date:1/19/2017)... 19, 2017 The Global Therapy Partnering Terms ... to partnering deals and agreements entered into by the ... deals - Top deals by value - Deals listed ... type The report provides understanding and access to ... world,s leading healthcare companies. The report provides an ...
Breaking Medicine Technology:
Cached News: