HOME >> MEDICINE >> NEWS
Margin Width The Key To Control Of Ductal Carcinoma In Situ Of The Breast

USC New England Journal Of Medicine Study Urges Caution In Use Of Radiation Therapy

LOS ANGELES, May 5, 1999 - Patients with one of the most common and curable forms of breast cancer may be undergoing radiation therapy unnecessarily, according to a University of Southern California study to be published in the May 13 New England Journal of Medicine.

The study, headed by Melvin J. Silverstein, M.D., medical director of the Harold E. and Henrietta C. Lee Breast Center at the USC/Norris Comprehensive Cancer Center, examines ductal carcinoma in situ (DCIS), a noninvasive breast cancer that has been the subject of a recent heated debate over treatment. Until 1980, DCIS was a relatively uncommon disease, representing only about 1 percent of all newly diagnosed cases of breast cancer. During the past two decades - as mammography has become more widely used and technically better - the number of new cases has increased dramatically.

Today DCIS represents as much as 40 percent of new breast cancer cases diagnosed by mammography, and estimates suggest that approximately 40,000 new cases of DCIS will be diagnosed this year in the U.S. Seventy to 80 percent of these patients are eligible for breast preserving lumpectomy rather than mastectomy. But opinion is currently divided on whether radiation therapy is necessary for all DCIS patients who choose lumpectomy.

In the NEJM article, Silverstein, a surgical oncologist, and colleagues found that radiation therapy does not appear to benefit patients where the margin width - the distance between the boundary of the lesion and the edge of the excised specimen - is 10 millimeters or more.

"Wide margin width makes complete excision more likely," says Silverstein. "Since DCIS is a noninvasive cancer that does not spread (metastasize), complete excision should cure the patient. These findings will have important ramifications for thousands of women with the disease. These data suggest that radi
'"/>

Contact: Mary Ellen Stumpl or Brenda Maceo
maceo@hsc.usc.edu
323-442-2830
University of Southern California
13-May-1999


Page: 1 2 3 4

Related medicine news :

1. Hopkins Institute for Global Tobacco Control receives elite recognition from PAHO/WHO
2. Controlling hormones could reduce risk of strokes in younger people
3. Controlling pain with your brain
4. Five more African countries to benefit from Schistosomiasis Control Initiative
5. Controlled study after Dutch caf fire highlights teen mental-health problems after disasters
6. Control valve within heart cells could protect body during heart attacks
7. Grant of 20 million to establish the Schistosomiasis Control Initiative
8. Controlled crying reduces infant sleep problems
9. Controlling blood pressure early prevents heart disease in elderly
10. AAPS Workshop to Examine Chemistry and Manufacturing Controls Trials, Emerging Products
11. Revolutionary New Procedure That Creates Controlled Heart Attack Performed For First Time In Southern California At Cedars-Sinai Medical Center

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Margin Width The Key Control Ductal Carcinoma Situ The Breast

(Date:8/28/2015)... ... August 28, 2015 , ... The Quatela Center for Plastic Surgery is excited ... only nonsurgical product approved by the Food and Drug Administration to eliminate submental fat, ... Dr. William Koenig are among the premier cosmetic surgeons in Rochester to offer ...
(Date:8/28/2015)... ... August 28, 2015 , ... Healthpointe clinics ... to go deep sea diving. The act of recreational diving exposes the ... these reasons, it is vital that all recreational and professional divers undergo regular ...
(Date:8/28/2015)... ... August 28, 2015 , ... United Benefit Advisors ... TJS Insurance Group as its newest Partner Firm. Founded in 1924 and headquartered ... them focused on their goals. Within the past 10 years, TJS Insurance Group ...
(Date:8/28/2015)... ... , ... Yisrayl Hawkins, Pastor and Overseer at The House of Yahweh in ... be taken in order to ease the stress on the atmosphere, and lessen the ... understand fully the real cause of global warming and urges them to look into ...
(Date:8/28/2015)... ... 2015 , ... An independent study recently conducted confirms that ... change to treatment recommendations and diagnosis. The 2015 return on investment (ROI) study ... analyzed WorldCare’s second opinion process. , The study reviewed cases across three representative ...
Breaking Medicine News(10 mins):Health News:Non-surgical Treatment to Get Rid of The "Double Chin," Kybella™, Now Available at the Quatela Center for Plastic Surgery 2Health News:Non-surgical Treatment to Get Rid of The "Double Chin," Kybella™, Now Available at the Quatela Center for Plastic Surgery 3Health News:Healthpointe Now Offering Scuba Physicals 2Health News:TJS Insurance Group Is Latest Partner Firm To Join United Benefit Advisors 2Health News:TJS Insurance Group Is Latest Partner Firm To Join United Benefit Advisors 3Health News:Wake Up and Smell the Sick Atmosphere Says Yisrayl Hawkins in New Article This Week 2Health News:WorldCare International, Inc. Celebrates Findings of Independent ROI Study 2
(Date:8/28/2015)... and PITTSBURGH , Aug. 28, ... today announced that its shareholders have approved Mylan,s ... PRGO ; TASE) and the related issuance of ... extraordinary general meeting of shareholders held today. The ... at the extraordinary general meeting. In addition, the ...
(Date:8/28/2015)... 2015 The global mHealth ... billion by 2020, growing at a CAGR of 47.6% ... by Grand View Research, Inc. Monitoring services is expected ... 2014 to 2020.      (Logo: http://photos.prnewswire.com/prnh/20150105/723757 ... rising incidences of chronic diseases such as cancer, heart ...
(Date:8/27/2015)... 2015 ieCrowd™ today announced the achievement ... of the company,s supplemental oxygen delivery device, Smart ... developed by ieCrowd,s subsidiary Smart Oxygen Solutions TM ... for oxygen based on level of activity.  The ... the Smart Oxygen device would require a series ...
Breaking Medicine Technology:Mylan Shareholders Overwhelmingly Approve Proposed Acquisition of Perrigo 2Mylan Shareholders Overwhelmingly Approve Proposed Acquisition of Perrigo 3Mylan Shareholders Overwhelmingly Approve Proposed Acquisition of Perrigo 4Mylan Shareholders Overwhelmingly Approve Proposed Acquisition of Perrigo 5Mylan Shareholders Overwhelmingly Approve Proposed Acquisition of Perrigo 6Mylan Shareholders Overwhelmingly Approve Proposed Acquisition of Perrigo 7Mylan Shareholders Overwhelmingly Approve Proposed Acquisition of Perrigo 8Mylan Shareholders Overwhelmingly Approve Proposed Acquisition of Perrigo 9mHealth Market is Expected to Reach $49.12 Billion By 2020: Grand View Research, Inc. 2mHealth Market is Expected to Reach $49.12 Billion By 2020: Grand View Research, Inc. 3mHealth Market is Expected to Reach $49.12 Billion By 2020: Grand View Research, Inc. 4mHealth Market is Expected to Reach $49.12 Billion By 2020: Grand View Research, Inc. 5Smart Oxygen Solutions' Supplemental Oxygen Delivery Device Achieves FDA Regulatory Pathway Milestone 2Smart Oxygen Solutions' Supplemental Oxygen Delivery Device Achieves FDA Regulatory Pathway Milestone 3Smart Oxygen Solutions' Supplemental Oxygen Delivery Device Achieves FDA Regulatory Pathway Milestone 4
Cached News: