HOME >> MEDICINE >> NEWS
Mayo Clinic researchers identify new form of muscular dystrophy in adults

ROCHESTER, Minn. -- Mayo Clinic researchers have identified a previously unknown form of muscular dystrophy, a group of genetic diseases characterized by progressive weakness and muscle degeneration. This newly identified form develops after age 40 and causes heart muscle damage, limb muscle weakness and nerve damage. The researchers have named the newly defined disorder "zaspopathy" (Zas-PO-path-ee).

Some 50,000 Americans have some form of muscular dystrophy, and there are currently no cures. Mayo Clinic researchers note that their work may help contribute to a cure because it increases the understanding of the muscular dystrophy disease process and the role genes play in it. They say their research is a crucial first step toward discovering treatments, because genes offer a promising target at which aim new therapies. The report on the discovery will appear in the Jan. 26 online version of the journal Annals of Neurology (http://www3.interscience.wiley.com/cgi-bin/jissue/78504407).

The Mayo Clinic researchers found that any one of three mutations in the gene that supplies the instructions for creating a protein known as " ZASP" can cause the newly defined disorder. The genes involved in zaspopathy are passed along to offspring in a dominant manner. This means that a child will develop the disorder by inheriting one copy of the mutant gene from one parent. The Mayo Clinic researchers tentatively named the new syndrome "zaspopathy" after the affected ZASP protein.

Significance of the Mayo Clinic Research

The identification of this new form of muscular dystrophy highlights the importance of scientific collaborations and the integration of different kinds of data. Laboratory information from ZASP alone was not enough to clarify the finding; clinical data from a large patient base was also necessary to support the clues given by ZASP. "The fact
'"/>

Contact: Lisa Lucier
newsbureau@mayo.edu
507-284-5005
Mayo Clinic
26-Jan-2005


Page: 1 2 3

Related medicine news :

1. Mayo Clinic discovers new pathway against pancreatic cancer
2. Mayo Clinic develops first genomic-based test to predict stroke from ruptured brain aneurysm
3. Mayo Clinic study sets threshold for valve repair surgery
4. Mayo Clinic researcher calls for improved newborn screening
5. Mayo Clinic study finds obese kidney donors face few increased risks
6. Mayo Clinic identifies key cellular process in prostate and other cancers
7. Clinical breast examination offers modest benefit to breast cancer screening program
8. Mayo Clinic researchers create obedient virus; First step to use measles virus against cancer
9. Clinicians report missing patient information is common
10. Mayo Clinic discovers a key to low metabolism and major factor in obesity
11. Clinical trial of Etanercept for Wegeners disease shows no benefit

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/29/2017)... ... April 29, 2017 , ... More than half of Americans ... Americans doing in their leisure time that causes hearing loss? May 1 marks the ... be contributing to hearing loss, as well as schedule a hearing evaluation for anyone ...
(Date:4/28/2017)... NY (PRWEB) , ... April 28, 2017 , ... It's ... there are a number of illnesses that are unclear as to whether or not ... their heads. Bronchitis is one of these illnesses. So, FindaTopDoc took a look into ...
(Date:4/28/2017)... ... April 28, 2017 , ... ... distribution of the GlycoMark test throughout the Northeast U.S. , GlycoMark is ... with diabetes. The GlycoMark test provides a clinically proven one- to two-week measure ...
(Date:4/28/2017)... KS (PRWEB) , ... April 28, 2017 , ... ... have typically been previously exposed to more adverse experiences than children in the ... experienced trauma such as abuse, neglect or other family challenges. While no fault ...
(Date:4/28/2017)... ... April 28, 2017 , ... Bill Howe started his sewer and drain company ... Tina Howe joined the team, the Bill Howe brand was born and they began ... and giving back to the San Diego community in which they worked, lived and ...
Breaking Medicine News(10 mins):
(Date:4/25/2017)... 25, 2017 Endo International plc (NASDAQ: ENDP ... Members of its senior management team will host a conference call ... ET. The dial-in number to access the call ... and the passcode is 6086379. Please dial in 10 minutes prior ... A replay of the call will be available from May 9, ...
(Date:4/24/2017)... Solentim, the developer of instrumentation for ... a major new product line called the VIPS™ ... has been developed for automatically seeding single cells ... of the process to generate clonally-derived cell lines. ... reliable solution when compared to traditional single cell ...
(Date:4/20/2017)... MINNEAPOLIS , April 20, 2017  Cogentix ... company focused on providing the Urology, Uro/Gyn and ... reported that Ash Keswani has joined the Company ... In this newly created position, Mr. Keswani will ... and CEO. "Our organization is delighted ...
Breaking Medicine Technology:
Cached News: