HOME >> MEDICINE >> NEWS
Mayo Clinic researchers identify new form of muscular dystrophy in adults

ROCHESTER, Minn. -- Mayo Clinic researchers have identified a previously unknown form of muscular dystrophy, a group of genetic diseases characterized by progressive weakness and muscle degeneration. This newly identified form develops after age 40 and causes heart muscle damage, limb muscle weakness and nerve damage. The researchers have named the newly defined disorder "zaspopathy" (Zas-PO-path-ee).

Some 50,000 Americans have some form of muscular dystrophy, and there are currently no cures. Mayo Clinic researchers note that their work may help contribute to a cure because it increases the understanding of the muscular dystrophy disease process and the role genes play in it. They say their research is a crucial first step toward discovering treatments, because genes offer a promising target at which aim new therapies. The report on the discovery will appear in the Jan. 26 online version of the journal Annals of Neurology (http://www3.interscience.wiley.com/cgi-bin/jissue/78504407).

The Mayo Clinic researchers found that any one of three mutations in the gene that supplies the instructions for creating a protein known as " ZASP" can cause the newly defined disorder. The genes involved in zaspopathy are passed along to offspring in a dominant manner. This means that a child will develop the disorder by inheriting one copy of the mutant gene from one parent. The Mayo Clinic researchers tentatively named the new syndrome "zaspopathy" after the affected ZASP protein.

Significance of the Mayo Clinic Research

The identification of this new form of muscular dystrophy highlights the importance of scientific collaborations and the integration of different kinds of data. Laboratory information from ZASP alone was not enough to clarify the finding; clinical data from a large patient base was also necessary to support the clues given by ZASP. "The fact
'"/>

Contact: Lisa Lucier
newsbureau@mayo.edu
507-284-5005
Mayo Clinic
26-Jan-2005


Page: 1 2 3

Related medicine news :

1. Mayo Clinic discovers new pathway against pancreatic cancer
2. Mayo Clinic develops first genomic-based test to predict stroke from ruptured brain aneurysm
3. Mayo Clinic study sets threshold for valve repair surgery
4. Mayo Clinic researcher calls for improved newborn screening
5. Mayo Clinic study finds obese kidney donors face few increased risks
6. Mayo Clinic identifies key cellular process in prostate and other cancers
7. Clinical breast examination offers modest benefit to breast cancer screening program
8. Mayo Clinic researchers create obedient virus; First step to use measles virus against cancer
9. Clinicians report missing patient information is common
10. Mayo Clinic discovers a key to low metabolism and major factor in obesity
11. Clinical trial of Etanercept for Wegeners disease shows no benefit

Post Your Comments:
(Date:8/1/2014)... Home Care Assistance of Cincinnati , a ... be recognized as a 2014 Best of Home Care Employer ... providers who rank in the top 50th percentile in one ... conducted by Home Care Pulse. , “The Best of ... best of the best!” says Home Care Pulse Founder and ...
(Date:8/1/2014)... Ticket Down is a reputable source for authentic ... Knoxville/Greenback, TN; Ingram Farms in Auburn/Opelika, AL; Cross Creek Place ... Luke Bryan is currently out on his summer “That’s My ... Bryan is responsible for one of the most popular country ... just because the summer is over doesn’t mean that when ...
(Date:8/1/2014)... of Bioengineering and Nanotechnology (IBN), Singapore General Hospital ... co-developed the first molecular test kit that can ... patients. This breakthrough was recently reported in ... , According to IBN Executive Director Professor ... molecular diagnostics and cancer research, we have developed ...
(Date:8/1/2014)... August 01, 2014 CapsCanada, a ... opening of a new K-CAPS® (HPMC capsules) manufacturing ... announced expansion plans last year while experiencing growing ... Martin, General Manager, “KCAPS® are currently sold in ... added that: “Compared to other HPMC capsules, K-CAPS® ...
(Date:8/1/2014)... Hills, CA (PRWEB) August 01, 2014 ... has found that carbohydrates may contribute to the ... genetically predisposed to the disease. The study was authored ... it, carbohydrates were found to cause intestinal cells to ... more susceptible to colorectal cancer. , “What’s interesting ...
Breaking Medicine News(10 mins):Health News:Cincinnati Senior Care Company Receives 2014 Best of Home Care® Employer of Choice Award 2Health News:Luke Bryan Tickets at Maple Lane Farms in Knoxville, Ingram Farms in Auburn, Cross Creek Place in Tallahassee & Whitehurst Cattle Farm in Gainesville Now Available 2Health News:Luke Bryan Tickets at Maple Lane Farms in Knoxville, Ingram Farms in Auburn, Cross Creek Place in Tallahassee & Whitehurst Cattle Farm in Gainesville Now Available 3Health News:Luke Bryan Tickets at Maple Lane Farms in Knoxville, Ingram Farms in Auburn, Cross Creek Place in Tallahassee & Whitehurst Cattle Farm in Gainesville Now Available 4Health News:Taking the guesswork out of cancer therapy 2Health News:Taking the guesswork out of cancer therapy 3Health News:Carbs May Contribute to Colon Cancer 2
(Date:7/31/2014)... 31, 2014  UBM Medica US announces that ... for oncologists, presents exclusive slide shows dealing with communication ... quality cancer care. Cancer Network, ... offers news, blogs, and podcasts about the latest clinical ... care: , End-of-life care is challenging for ...
(Date:7/31/2014)... 2014  Decision Resources Group is launching an extension ... to now include ChinaTrack; the new capabilities track the ... interactive dashboard providing detailed brand-level share tracking and analytics. ... level. Other key capabilities of the new ... addition to end-user surveys of healthcare facilities, ChinaTrack data ...
(Date:7/31/2014)... Lazarus Effect, a medical device company focused ... removal of blood clots, announced the closing of a ... EU commercialization of several approved Lazarus Effect devices, as ... Lazarus Cover™ in the United States ... the value of our novel, platform technology as well ...
Breaking Medicine Technology:Cancer Network Highlights Methods Oncologists Can Use to Improve Communication 2Cancer Network Highlights Methods Oncologists Can Use to Improve Communication 3Decision Resources Group Announces First Medical Device Account Targeting Tool in China 2Lazarus Effect Closes $5 Million Financing 2
Cached News: