HOME >> MEDICINE >> NEWS
Mayo Clinic scientists discover way to enhance immune system that repairs nervous system in mouse model

ROCHESTER, MINN. -- In a major scientific discovery, Mayo Clinic scientists conducting research in mice with central nervous system damage have found a way to enhance the immune system that resulted in nervous system repair in the mice. The study detailing the findings will be published in the Tuesday, June 6 edition of Proceedings of the National Academy of Sciences.

In their study, Mayo Clinic scientists identified two natural human antibodies that, when given to mice with a chronic, demyelinating disease, caused the regrowth and repair of the myelin sheath. Myelin surrounds nerve fibers and acts as "insulation," allowing them to function properly. Previously, it was thought that damage to myelin was permanent and repair to the nervous system was not possible. In humans, damage to the myelin sheath can be caused by traumatic injury or by diseases such as multiple sclerosis, transverse myelitis and other demyelinating or genetic conditions.

"Clearly, our study shows that the two natural human antibodies, when introduced into mice that had nervous system damage, safely caused substantial repair to the myelin and the nervous system," says Moses Rodriguez, M.D., a Mayo Clinic neurologist and the principal author of the study. "This is a significant step forward in our understanding of the nervous system and the immune system. Whereas we know that the immune system can have a protective effect on the body, we now are beginning to discover that the immune system may be harnessed to effect repair to the nervous system in the mouse model."

In the laboratory study, mice were injected with a virus that caused demyelination in the nervous system similar to the damage multiple sclerosis causes in humans. The mice were treated with two natural human monoclonal antibodies after the onset of demyelination. This treatment promoted remyelination to an equivalent or greater extent than human intravenous immunoglobulin (IVIg), an established treatmen
'"/>

Contact: Jane Jacobs
newsbureau@mayo.edu
507-284-2387
Mayo Clinic
4-Jun-2000


Page: 1 2

Related medicine news :

1. Mayo Clinic discovers new pathway against pancreatic cancer
2. Mayo Clinic develops first genomic-based test to predict stroke from ruptured brain aneurysm
3. Mayo Clinic study sets threshold for valve repair surgery
4. Mayo Clinic researcher calls for improved newborn screening
5. Mayo Clinic study finds obese kidney donors face few increased risks
6. Mayo Clinic identifies key cellular process in prostate and other cancers
7. Clinical breast examination offers modest benefit to breast cancer screening program
8. Mayo Clinic researchers create obedient virus; First step to use measles virus against cancer
9. Clinicians report missing patient information is common
10. Mayo Clinic discovers a key to low metabolism and major factor in obesity
11. Clinical trial of Etanercept for Wegeners disease shows no benefit

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:9/3/2020)... ARLINGTON, Va. (PRWEB) , ... September 03, 2020 ... ... enterprise imaging in radiology will be the focus of Fall 2020 Virtual Conference, ... by AuntMinnie.com. , "AI, Enterprise Imaging & Beyond" is the follow-up to ...
(Date:9/3/2020)... ... September 03, 2020 , ... MemoryCare.com, a ... the Best Memory Care Facilities in Louisville, KY. The guide identifies 17 memory ... , According to the Alzheimer’s Association , 5.6 million people age 65 ...
(Date:9/2/2020)... WASHINGTON, Pa. (PRWEB) , ... September 02, 2020 ... ... development of enterprise software for healthcare payers administering Medicare Advantage and Special Needs ... Duals Online presented by America’s Health Insurance Plans (AHIP). RAM is supporting the ...
(Date:9/1/2020)... ... , ... KitoTech Medical, a Seattle-based medical device company, announced ... used to accelerate the commercialization of its microMend® family of wound closure products. ... expand its customer base of healthcare systems as well as independent hospitals and ...
(Date:9/1/2020)... ... September 01, 2020 , ... As fall and winter ... Cohn Health Institute has taken this time to expand and grow into ... 30th Anniversary, the Cohn Health Institute will be relaunching its brand new website, expanding ...
Breaking Medicine News(10 mins):
(Date:9/1/2020)... ... 01, 2020 , ... September is National Ovarian Cancer Awareness Month. Ovarian ... other cancer of the female reproductive system. The American Cancer Society estimates that ... women will die from this disease. Throughout the month of September, Women’s Excellence ...
(Date:8/31/2020)... ... August 31, 2020 , ... ... advisory guide, has named Cloudticity a Gold winner in the 15th Annual 2020 ... peer recogniti o ns from Network Products Guide honoring achievements of ...
(Date:8/27/2020)... Pa. (PRWEB) , ... August 27, 2020 , ... ... care coordination software, today announced the successful completion of their 2020 System and ... well as their HITRUST® interim assessment and MARS-E compliance assessment. These achievements reflect ...
Breaking Medicine Technology:
Cached News: