HOME >> MEDICINE >> NEWS
Mayo Clinic study sets threshold for valve repair surgery

"We know from previous studies that patients with symptomatic mitral regurgitation are at increased risk of death, but for those without symptoms the picture has been murkier," says Maurice Enriquez-Sarano, M.D., the Mayo Clinic cardiologist who led the study. "In this study we followed a large population of asymptomatic patients prospectively to identify keys to improved long-term outcomes, and to determine when patients should consider surgery."

The mitral valve separates the left upper chamber of the heart (atrium) from the left lower chamber (ventricle). In mitral regurgitation this valve does not close properly, which causes some blood to backwash into the heart from the left ventricle instead of being pumped out to the rest of the body. The left atrium typically enlarges due to this pressure, and as a result of this compensation the patient may not experience symptoms initially. As the disease progresses, symptoms may include fatigue, exhaustion, light-headedness, shortness of breath and heart palpitations.

Mitral regurgitation of moderate degree or more is frequent, particularly in the aging population. It is estimated that 2 to 2.7 million Americans are afflicted by this condition and that this number will rise to 3.8 to 4.8 million Americans by 2030.

The Mayo Clinic researchers used Doppler echocardiography ultrasound images of the heart and its blood flow patterns to determine which physical characteristics predicted patient outcomes. Age and diabetic status were strongly associated with poorer outcomes. However, the most important finding was that the effective regurgitant orifice area the cross-sectional size of the jet stream of blood backwashing into the atrium was the strongest determinant of outcome.

Patients with a regurgitant orifice larger than 40 mm2 who were treated only with medication were more than five times more likely to die than those with the same severity of regurgitation who underwent valve repair s
'"/>

Contact: Lee Aase
newsbureau@mayo.edu
507-284-5005
Mayo Clinic
2-Mar-2005


Page: 1 2

Related medicine news :

1. Mayo Clinic discovers new pathway against pancreatic cancer
2. Mayo Clinic develops first genomic-based test to predict stroke from ruptured brain aneurysm
3. Mayo Clinic researcher calls for improved newborn screening
4. Mayo Clinic study finds obese kidney donors face few increased risks
5. Mayo Clinic identifies key cellular process in prostate and other cancers
6. Clinical breast examination offers modest benefit to breast cancer screening program
7. Mayo Clinic researchers create obedient virus; First step to use measles virus against cancer
8. Clinicians report missing patient information is common
9. Mayo Clinic discovers a key to low metabolism and major factor in obesity
10. Clinical trial of Etanercept for Wegeners disease shows no benefit
11. Mayo Clinic researchers identify new form of muscular dystrophy in adults

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/26/2020)... ANGELES (PRWEB) , ... May 26, 2020 , ... Sex ... and ageless sexuality advocate Joan Price have just received the 2020 AASECT Audio Visual ... sex education film was the first of its kind to feature non-actors in its ...
(Date:5/25/2020)... ... May 23, 2020 , ... Winemaker Grant Long Jr. is introducing ... present something whimsical and delicious in these complicated times,” he said, in announcing the ... 2018 Grenache ($24.99). The Chardonnay and Red Wine Blend are sourced in the Napa ...
(Date:5/21/2020)... ... May 21, 2020 , ... In response to the Coronavirus pandemic, Industrial ... users to open swing-style doors without using their hands or fingertips. , ... door open using their forearm, wrist or elbow when entering or exiting a room. ...
(Date:5/21/2020)... ... May 21, 2020 , ... Fujirebio ... in cancer biomarker assays, announced today that Cigna has added ROMA® (Risk of ... global health service company dedicated to improving the health, well-being, and peace of ...
(Date:5/21/2020)... ... May 21, 2020 , ... A Safe Haven Foundation ... from the $5 million AbbVie COVID-19 Community Resilience Fund. The fund was created in ... of their frontline homeless workers in service to vulnerable populations in hard-hit communities. ...
Breaking Medicine News(10 mins):
(Date:6/3/2020)... (PRWEB) , ... June 03, 2020 , ... ... from the ADA Generation, comparing the workplace experiences of recent graduates with and ... national survey of college graduates with disabilities coming of age under the Americans ...
(Date:6/3/2020)... ... June 03, 2020 , ... ... has launched the cutting edge CheckIn2Work app, a first of its kind technology ... professionals. The app delivers a quick and easy self-service health attestation for organizations ...
(Date:6/3/2020)... ... June 03, 2020 , ... For over 50 years, Divi Resorts ... strict cleaning and hygiene protocols at all of their resorts to ensure guests ... and cleanliness procedures to safeguard and protect both guests and staff and address changing ...
Breaking Medicine Technology:
Cached News: