HOME >> MEDICINE >> NEWS
Media focus on endostatin helped -- not hurt --

that heralded the discovery and development of an agent called recombinant human endostatin (rh-Endo), an angiogenesis inhibitor designed to dry up a tumor's source of blood, starving it. In the article, researchers predicted endostatin might quickly prove to be a cure for cancer. The media blitz that followed was unusual in medical reporting because the drug had not been formally tested in humans.

When M. D. Anderson researchers geared up to run a small Phase I clinical trial of rh-Endo -- one of three centers in the country to conduct such a study -- they were ethically concerned that such "hyperbolic" coverage both in 1998 and at the launch of the clinical trials might draw patients who had little understanding of the purpose of a Phase I clinical trial, but were solely focused on the drug's ability to save their lives. Patients admitted into this beginning phase of testing have no curative treatment options, yet these trials are designed to determine safety and optimal dose, and monitor effectiveness -- it is not intended to prove clinical benefit.

To see if their worries were justified, they asked patients who were referred to the trial from physicians at M. D. Anderson to participate in a survey. Some of these patients were not being cared for at M. D. Anderson, but subsequently contacted the cancer center in the hopes of being seen and referred to the trial.

The seven-member ethics research team analyzed media coverage of the agent from 1997 to 2000 in three newspapers known for medical reporting -- The New York Times, Boston Globe and Chicago Tribune. They found that the majority of coverage was generally positive on the promise of endostatin -- only 25 percent of the articles gave what researchers called a "factual account."

They then surveyed 100 patients referred to the endostatin trial between October 1999 and November 2000. Almost half of survey participants (47 percent) had heard about endostatin from media sources, and 51 pe
'"/>

Contact: Julie Penne or Laura Sussman
jpenne@mdanderson.org
713-792-0655
University of Texas M. D. Anderson Cancer Center
13-Sep-2002


Page: 1 2 3 4

Related medicine news :

1. Media update: GSA underscores hottest meeting topics
2. Media invitation first annual EDCTP Forum
3. Media invitation - European Society of Cardiology Congress 2004
4. Media invitation: The Movement Disorder Societys 7th International Congress
5. Media Advisory-- Results of California autism epidemiology study to be unveiled
6. Review of preliminary observations concludes the Mayo Clinic Natl Conf on Medicine and the Media
7. Media undermine efforts to tackle nicotine addiction
8. Media advisory: Mayo Clinic study finds infliximab safe and beneficial for Crohns disease
9. Media coverage of new drugs is often misleading
10. Media advisory: Mayo Clinic study shows increased incidence of migraines in women
11. American Heart Association Media Advisory: Cholesterol Lowering Margarines

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Media focus endostatin helped not hurt

(Date:6/30/2015)... ... June 30, 2015 , ... ... Rehab”. The video focuses on the rehab center’s patients and their experiences at ... the best quality of services available. Each patient attests to the high rating, ...
(Date:6/30/2015)... ... June 30, 2015 , ... Broadway by the Sea posted its ... and family member testimonials. Medicare rated the care center as a five-star location based ... video to give future patients a firsthand look at the facility’s satisfied residents. ...
(Date:6/30/2015)... (PRWEB) , ... June 30, 2015 , ... ... ) currently pending in a federal multidistrict litigation now underway in the U.S. ... its next monthly Status Conference. According to the Court’s calendar, that conference has ...
(Date:6/30/2015)... ... June 30, 2015 , ... Allied ... from Allied’s Fullerton division volunteered to help provide free outpatient procedures to some ... 21, at St. Jude Medical Center. , The event was coordinated by ...
(Date:6/30/2015)... ... June 30, 2015 , ... Red Hot & Blue Restaurants, ... online poll at http://scoutology.com/novaburgerwars and was selected as “Best BBQ” in a ... 2015. , Red Hot & Blue President Randy McCann said, “Everyone knows Red Hot ...
Breaking Medicine News(10 mins):Health News:Patients of University Post-Acute Rehab Support Five-Star Rating in New Video 2Health News:Broadway by the Sea Video Promotes Top Quality Service 2Health News:Progress of Federal Xarelto Lawsuits Pending in Multidistrict Litigation to Be Discussed During July 9th Status Conference 2Health News:Progress of Federal Xarelto Lawsuits Pending in Multidistrict Litigation to Be Discussed During July 9th Status Conference 3Health News:Allied Anesthesia Physicians Volunteer to Help Orange County’s Uninsured During Annual Super Surgery Saturday 2Health News:Allied Anesthesia Physicians Volunteer to Help Orange County’s Uninsured During Annual Super Surgery Saturday 3Health News:Red Hot & Blue BBQ Restaurants Voted "Best Burger" in Virginia and "Best Barbecue" in Texas 2Health News:Red Hot & Blue BBQ Restaurants Voted "Best Burger" in Virginia and "Best Barbecue" in Texas 3
(Date:6/30/2015)... BERKELEY, Calif. and COPENHAGEN, ... CMC Biologics, Inc. , a global leader in clinical ... proteins, announced today that, as part of its global ... of its North American manufacturing facility in ... single-use Bioreactor 6Pack™ facility.  The Bioreactor 6Pack™ configuration consists ...
(Date:6/30/2015)... 2015 Legal-Bay LLC, the Lawsuit Settlement Funding ... the multidistrict litigation (MDL) over the Zimmer NexGen Knee ... th , 2015. There are currently more than a ... before a federal judge in Illinois ... will begin in October of this year. Zimmer Inc. ...
(Date:6/29/2015)... -- Mordor Intelligence presents their Global Pharmaceutical ... Glass, Paper, Metal) - ByType of Packaging (Ampules, Blister Packs, ... Sachets) - By Geographical Region ( North America ... , Latin America , ... - discussing Industry Value Chain Analysis, Porter,s 5 Force Analysis, ...
Breaking Medicine Technology:CMC Biologics Expands GMP Manufacturing Capacity in the United States 2CMC Biologics Expands GMP Manufacturing Capacity in the United States 3Legal-Bay Lawsuit Settlement Funding Reports Zimmer NexGen Knee Bellwether Trial to Begin October 13th, 2015 2Legal-Bay Lawsuit Settlement Funding Reports Zimmer NexGen Knee Bellwether Trial to Begin October 13th, 2015 3Global Pharmaceutical Packaging Market - North America and Europe Expected to Lead Followed by the Asia Pacific Market 2Global Pharmaceutical Packaging Market - North America and Europe Expected to Lead Followed by the Asia Pacific Market 3
Cached News: