HOME >> MEDICINE >> NEWS
Media focus on endostatin helped -- not hurt --

that heralded the discovery and development of an agent called recombinant human endostatin (rh-Endo), an angiogenesis inhibitor designed to dry up a tumor's source of blood, starving it. In the article, researchers predicted endostatin might quickly prove to be a cure for cancer. The media blitz that followed was unusual in medical reporting because the drug had not been formally tested in humans.

When M. D. Anderson researchers geared up to run a small Phase I clinical trial of rh-Endo -- one of three centers in the country to conduct such a study -- they were ethically concerned that such "hyperbolic" coverage both in 1998 and at the launch of the clinical trials might draw patients who had little understanding of the purpose of a Phase I clinical trial, but were solely focused on the drug's ability to save their lives. Patients admitted into this beginning phase of testing have no curative treatment options, yet these trials are designed to determine safety and optimal dose, and monitor effectiveness -- it is not intended to prove clinical benefit.

To see if their worries were justified, they asked patients who were referred to the trial from physicians at M. D. Anderson to participate in a survey. Some of these patients were not being cared for at M. D. Anderson, but subsequently contacted the cancer center in the hopes of being seen and referred to the trial.

The seven-member ethics research team analyzed media coverage of the agent from 1997 to 2000 in three newspapers known for medical reporting -- The New York Times, Boston Globe and Chicago Tribune. They found that the majority of coverage was generally positive on the promise of endostatin -- only 25 percent of the articles gave what researchers called a "factual account."

They then surveyed 100 patients referred to the endostatin trial between October 1999 and November 2000. Almost half of survey participants (47 percent) had heard about endostatin from media sources, and 51 pe
'"/>

Contact: Julie Penne or Laura Sussman
jpenne@mdanderson.org
713-792-0655
University of Texas M. D. Anderson Cancer Center
13-Sep-2002


Page: 1 2 3 4

Related medicine news :

1. Media update: GSA underscores hottest meeting topics
2. Media invitation first annual EDCTP Forum
3. Media invitation - European Society of Cardiology Congress 2004
4. Media invitation: The Movement Disorder Societys 7th International Congress
5. Media Advisory-- Results of California autism epidemiology study to be unveiled
6. Review of preliminary observations concludes the Mayo Clinic Natl Conf on Medicine and the Media
7. Media undermine efforts to tackle nicotine addiction
8. Media advisory: Mayo Clinic study finds infliximab safe and beneficial for Crohns disease
9. Media coverage of new drugs is often misleading
10. Media advisory: Mayo Clinic study shows increased incidence of migraines in women
11. American Heart Association Media Advisory: Cholesterol Lowering Margarines

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/24/2016)... ... 2016 , ... A recent article published June 14 on E ... goes on to state that individuals are now more comfortable seeking to undergo not ... as calf and cheek reduction. The Los Angeles area medical group, Beverly Hills Physicians ...
(Date:6/24/2016)... ... , ... Marcy was in a crisis. Her son James, eight, was out of control. Prone ... physically. , “When something upset him, he couldn’t control his emotions,” remembers Marcy. “If ... at my other children and say he was going to kill them. If we ...
(Date:6/24/2016)... ... June 24, 2016 , ... ... micro-osteoperforation for accelerated orthodontic treatment. Dr. Cheng has extensive experience with all areas ... , AcceleDent, and accelerated osteogenic orthodontics. , Micro-osteoperforation is a revolutionary adjunct ...
(Date:6/24/2016)... ... , ... People across the U.S. are sharpening their pencils and honing their ... in which patients and their families pay tribute to a genetic counselor by nominating ... of Genetic Counselors (NSGC) Annual Education Conference (AEC) this September. , In April, ...
(Date:6/24/2016)... , ... June 24, 2016 , ... ... The Grove Investment Group (TGIG), has initiated cultivation and processing operations at its ... Vegas and Pahrump, Nevada. , Puradigm is the manufacturer of a complete system ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... 24, 2016 Research and Markets has ... Companion Diagnostic Tests" report to their offering. ... Diagnostics The World Market for Companion Diagnostics ... diagnostics. Market analysis in the report includes the following: ... Vitro Diagnostic Kits) by Region (N. America, EU, ROW), 2015-2020 ...
(Date:6/24/2016)... , Belgium , June ... MKT: VNRX), today announced the appointment of Dr. ... of Directors as a Non-Executive Director, effective June ... Company,s Audit, Compensation and Nominations and Governance Committees.  ... Dr. Futcher will provide independent expertise and strategic ...
(Date:6/23/2016)... Research and Markets has announced the addition of the ... report to their offering. ... failure, it replaces the function of kidneys by removing the ... the treatment helps to keep the patient body,s electrolytes such ... Increasing number of ESRD patients & substantial healthcare expenditure on ...
Breaking Medicine Technology:
Cached News: