HOME >> MEDICINE >> NEWS
Medical molecules designed to respond to visible light that can penetrate tissue

Blacksburg, Va. -- If you have ever covered a flashlight with your hand and seen the red light that still comes through, then you have seen light in the therapeutic window that magic wavelength that is not absorbed or reflected away by tissue. Scientists believe that they can use light at that wavelength to signal manmade molecules to release drugs at disease sites in the body.

Such possibilities will be discussed in a poster and a talk by Virginia Tech researchers presenting at the 229th American Chemical Society national meeting in San Diego on March 13-17.

Researchers in Karen Brewer's group at Virginia Tech have designed supramolecular complexes that can hold and, when signaled by light (photoinitiatied), will generate pharmaceutical compounds that can cleave DNA, such as in a tumor cell. "The challenge has been that tissue blocks light so we can't signal molecules deep within the body to deliver drug therapy," says Brewer, associate professor of chemistry.

Matthew Mongelli of Maywood N.J., a postdoctoral associate in chemistry, and his colleagues in chemistry and biology at Virginia Tech, have been working with Theralase Technologies Inc. to design molecular systems that use light that is in the therapeutic window. Starting with a complex with known DNA cleaving qualities, they changed the light absorber unit to one that responds to the red wavelength.

"Investigations into polyazine supermolecular complexes containing Ru and Os with Rh centers that possess photoactive MMCT states: Visible light induced, oxygen independent DNA photocleavage (INOR 329)," will be presented by Mongelli during the general poster session, 7 to 9 p.m., Sunday, March 13, in Convention Center Hall D. The poster has also been selected for the Sci_Mix session 7 to 9 p.m. Monday, March 14, in the Convention Center's Sails Pavilion.

Co-authors are Brewer; undergraduate chemistry students Matthew Jeletic of Centreville, Va. and Jerita Dubash of Ashbur
'"/>

Contact: Susan Trulove
STrulove@vt.edu
540-231-5646
Virginia Tech
13-Mar-2005


Page: 1 2

Related medicine news :

1. Medically supervised drug injection facilities safer for users
2. Philanthropist Paul F. Glenn launches labs for aging research at Harvard Medical School
3. UCLA Medical Center becomes first hospital to introduce remote presence robots in ICU
4. New data on Orqis Medicals Cancion CRS to be reported at ACC
5. Medical technologies may hinder rather than help newborn survival
6. Medical meeting to feature research findings and disease prevention and health promotion sessions
7. LA BioMed Medical/Research briefs January 2005
8. Medical negligence system is secretive, unaccountable and unregulated
9. Dartmouth Medical School receives $1.6 million in AIDS funding
10. LA BioMed Medical/Research Briefs December 2004
11. Rush University Medical Center testing magnetic stimulation for depression

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/25/2019)... ... March 25, 2019 , ... Terry L. Mathis, founder and chief executive ... 12, 2019. The annual conference promotes the highest levels of aviation safety, covering current ... descriptive but not prescriptive. A company does not automatically progress along the curve ...
(Date:3/24/2019)... ... ... those pesky molars that cause pain and swollen jaws, is a very common dental procedure ... being pulled?” Nipomo dentist, Dr. Perry Patel answers the top questions patients have ... begin to appear between the ages of 17 and 21. These teeth are called “wisdom ...
(Date:3/23/2019)... KING OF PRUSSIA, Pa. (PRWEB) , ... March ... ... the nation’s top healthcare companies and part of WPP (NYSE:WPP), is celebrating its ... the company’s future growth. CMI/Compas has reached a major milestone of growth and ...
(Date:3/23/2019)... CAMP HILL, Pa. (PRWEB) , ... March 22, 2019 , ... ... the West Shore Plaza in Lemoyne on Saturday, April 13, from 10:00 a.m. to ... tips for healthy living, fitness sessions, healthy food samples, games, and giveaways for every ...
(Date:3/20/2019)... ... March 20, 2019 , ... It’s not Easter without the Easter ... spring holiday season. From April 6 through April 20, the Easter Bunny will greet ... year, the Bunny Hut brings so much joy to Grossmont Center,” says Trevor Moore, ...
Breaking Medicine News(10 mins):
(Date:3/26/2019)... (PRWEB) , ... March 26, 2019 , ... Clarion Safety ... and tags , has launched a new Referral Program, collaborating with the American ... Program , when clients refer the company’s best practice safety products to a safety ...
(Date:3/25/2019)... (PRWEB) , ... March 25, 2019 , ... A March 1 article on ... influence of social media but also in an effort to stand out in a competitive ... plastic surgery in order to gain any advantage possible in the workforce against their peers, ...
(Date:3/25/2019)... ... ... Nexus Recovery Services has published a comprehensive infographic entitled “How-to Support Someone in ... on their journey of recovery from substance abuse and addiction. , With this ... safe environment, work on relationships, and take care of yourself when a loved one ...
Breaking Medicine Technology:
Cached News: