Melanoma Patients' Sentinel Lymph Nodes (SLNS) Play A Strong Role In Disease Prognosis, UCSF Study Reports

ATLANTA -- Researchers at the University of California San Francisco report that melanoma patients whose cancer has spread to their sentinel lymph nodes (SLNs) have a greater chance of experiencing disease recurrence and mortality compared to those whose cancer has not advanced to their SLNs.

The sentinel lymph node (SLN) earned its name because it is the first region in a person's body that receives cancer cells from the place where the disease originated. After cancer cells drain to the SLN, the disease may spread, or metastasize, to other regions of the body. Lymph nodes are the body's first line of defense against infections and cancers. They produce infection-fighting lymphocytes that are distributed via the lymphatic system that functions as a channel of freeways throughout the body.

"Sentinel lymph nodes are a strong marker for predicting a patient's outcomes in regards to disease recurrence and death due to advanced melanoma," says Stanley P.L. Leong, MD, FACS, UCSF professor of surgery and director of the Sentinel Lymph Node program in the UCSF Cancer Center. "We found that patients who have a positive SLN biopsy are more likely to experience a disease recurrence and die from melanoma than those with a negative SLN biopsy."

Leong will present data on the role of SLNs in melanoma today at the American Society for Clinical Oncology (ASCO) meeting.

During the UCSF study, a total of 358 advanced melanoma patients underwent a selective SLN dissection and were followed for a median period of 546 days.

Leong reports that for patients whose cancer spread to their SLNs and therefore had a positive SLN biopsy (63), 78 percent had no evidence of disease and 22 percent experienced recurrent melanoma. Eighty-six percent of these patients remained alive and 14 percent (9) died from melanoma by the end of the study.

For patients with negative SLNs (295), 93 percent showed no evidence of disease and 7 percent developed a recurrence of the dis

Contact: Abby Sinnot
University of California - San Francisco

Page: 1 2 3

Related medicine news :

1. Melanoma vaccine developed at the University of Virginia shows promise in clinical trial
2. University Of Pittsburgh Cancer Institute Defines First Immunologic Markers Of Interferon Effectiveness Against Melanoma
3. Jefferson Researchers Report Progress In Using Vaccinia-Based Vaccine For Melanoma
4. Vaccine Against Melanoma Proves Successful For Patients With Disease Spread To Two Lymph Node Areas
5. DNA-Based Cancer Vaccine Shows Promise To Successfully Treat Melanoma In Mice
6. Caregivers, remember this: Patients medications ease your distress too
7. Patients anaesthesia concerns reviewed
8. Heal thyself: Patients bone marrow cells restore failing hearts
9. Initial Avon/NCI breast cancer research grants awarded in Progress for Patients awards program
10. Patients beliefs and behaviors about health lifestyle and medications may help tailor high blood pressure management method
11. Relaxation And Music Significantly Reduce Patients Postoperative Pain

Post Your Comments:

(Date:10/11/2019)... (PRWEB) , ... October 11, 2019 , ... Inland Detox, ... Temecula, CA. The new location has incredible views of the Temecula Valley and it’s ... 2.5 acres, the new facility offers both private rooms as well as double occupancy ...
(Date:10/10/2019)... ... 2019 , ... AltMed Florida , one of the fastest growing Medical ... grand opening of its second MÜV™ Medical Cannabis Dispensary on the First Coast – ... Jacksonville Beach. , Located at Beach Plaza Shopping Center at the corner of Beach ...
(Date:10/10/2019)... , ... October 10, 2019 , ... Caring.com, a leading ... on the Best and Worst Places for Seniors to Live. All 50 states and ... transportation, quality of life and workforce development. , According to the U.S. ...
(Date:10/8/2019)... Calif. (PRWEB) , ... October 08, 2019 , ... ... stores - Kroger, Ralphs, QFC and Fred Meyer, King Sooper, Fry’s, Roundy’s, Smiths ... Whole30 approved, dairy-free, grain-free & gluten-free. , “Ingredient purity and fresh taste ...
(Date:10/8/2019)... ... October 08, 2019 , ... SoCal Adolescent Wellness announces the opening of a ... of our services to better serve the families in Orange County," said Becca Moody, ... see the extraordinary impact this pre-intervention program has on the lives of the adolescents ...
Breaking Medicine News(10 mins):
(Date:10/8/2019)... ... October 08, 2019 , ... ... farmers a wider range of novel, microbial-based crop protection products. , Under the ... natural product starting points. In a first for the agriculture industry, Corteva will ...
(Date:10/8/2019)... ... October 08, 2019 , ... ... today announced that FocalPoint Holdings, a privately-held investment and management firm specializing ... more than 8,000 ophthalmology and optometry providers Luma Health’s patient relationship technology ...
(Date:10/8/2019)... ... October 08, 2019 , ... AdventHealth Wesley ... and provide safer, convenient options for patients who require treatment. The hospital is ... enhanced mammography is used to detect tumors in dense breasts that may not ...
Breaking Medicine Technology:
Cached News: