Metabolic 'footprint' may be new measure of obesity risk in kids

SAN FRANCISCO, March 5 Levels of a fat protein, called adiponectin, which is linked to heart disease in adults, is significantly lower in overweight children and young adults, researchers said today at the American Heart Association's 44th annual Conference on Cardiovascular Disease Epidemiology and Prevention.

Adiponectin was an important discriminator between obese and normal-weight children, said Sandra G. Hassink, M.D., assistant professor of pediatrics at Thomas Jefferson University in Philadelphia, who presented the study.

"Factors such as cholesterol, blood pressure, triglyceride levels and measures of insulin sensitivity were not meaningful in differentiating between these two groups," she said.

But the study showed that adiponectin may be part of a "footprint" for heart disease risk in children.

"While obesity is a known risk factor for heart disease and diabetes, we don't know what factors determine which obese people are at greatest risk," said Hassink, who is also director of the Pediatric Weight Management Program at A.I. Dupont Hospital in Wilmington, Del. "The evidence is beginning to point to adiponectin as a key player in determining true risk," she said.

Adiponectin adheres to blood vessel walls, possibly protecting them by fighting inflammation at a cellular level. "Lower levels of adiponectin mean less protection for blood vessels, which may lead to adult heart disease," Hassink said.

The study included 23 normal-weight children (body mass indices, or BMI, below the 85th percentile) and 48 obese children (BMI above the 95th percentile). Five of the children were Hispanic, 15 African American and 51 Caucasian.

Besides lower adiponectin levels, the overweight children had significantly higher erythrocyte sedimentation rates or (ESR a marker for inflammation), higher total cholesterol and higher levels of leptin, a protein involved in regulating weight.

The adiponectin level in normal-weight children

Contact: Carole Bullock
American Heart Association

Page: 1 2

Related medicine news :

1. Metabolic syndrome associated with cognitive decline in elderly persons
2. Metabolic syndrome, not BMI, predicts future cardiovascular risk in obese women, study finds
3. Metabolic syndrome predicts heart risk in women with coronary artery disease, study finds
4. Metabolic syndrome may be an important link to stroke
5. Metabolic syndrome strongly linked to heart attack and stroke
6. Hopkins researcher finds retroviral footprint in brains of people with schizophrenia
7. University of Manchester makes made-to-measure skin and bones a reality using inkjet printers
8. Size of myocardial infarct measured using MRI
9. Study finds women hesitant to take tamoxifen as preventive measure
10. How are we doing? Researchers aim to measure national well being
11. Study finds computer vignette to be effective way to measure quality of physician practice

Post Your Comments:

(Date:10/13/2017)... ... October 13, 2017 , ... ... PharmD ‘17, and Jennifer Huggins, PharmD ’17, along with clinical associate professor ... prevention of cardiovascular diseases during the 15th Annual Women’s Health Conference. The ...
(Date:10/13/2017)... Shelton, CT (PRWEB) , ... October 13, 2017 , ... ... and long-term care services, staged a mock evacuation of the facility as part of ... Department, Shelton Fire Department, Echo Hose EMS and Shelton City Emergency Manager, as well ...
(Date:10/13/2017)... ... October 13, 2017 , ... The Visiting Nurse Association (VNA) ... a collection of specialty vendors and unique items from across the nation, this holiday-themed ... and wellness services offered by the VNA. The boutique will be open Saturday, ...
(Date:10/13/2017)... ... October 13, 2017 , ... Global Healthcare Management’s 4th Annual ... in Milford, NJ. This free event, sponsored by Global Healthcare Management’s CEO, Jon ... fun run is geared towards children of all ages; it is a non-competitive, non-timed ...
(Date:10/13/2017)... ... October 13, 2017 , ... ... giving viewers the lowdown on sciatica in a new episode of "Success Files," ... on current events and innovation and investigates each subject in-depth with passion and ...
Breaking Medicine News(10 mins):
(Date:10/11/2017)... IRVING, Texas , Oct. 11, 2017  Caris ... science focused on fulfilling the promise of precision medicine, ... Institute has joined Caris, Precision Oncology Alliance™ (POA) as ... leading cancer centers, the St. Jude Crosson Cancer Institute ... to advance the use of tumor profiling, making cancer ...
(Date:10/7/2017)... 6, 2017   Provista, a proven leader ... billion in purchasing power, today announced a new resource ... The Newsroom is the online home for case ... expert bios, news releases, slideshows and events. ... wealth of resources at their fingertips, viewers can also ...
(Date:10/2/2017)... Oct. 2, 2017 Diplomat Pharmacy, Inc. (NYSE: ... Software and Consulting, LLC , and named its founder ... based in Tennessee , will operate ... expands EnvoyHealth,s service offerings for health care partners to ... "In an interoperable world, technology ...
Breaking Medicine Technology:
Cached News: