Metabolic 'footprint' may be new measure of obesity ri...( averaged 30.4 micrograms per milliliter...),Health

averaged 30.4 micrograms per milliliter of blood (g/ml) and 21.6 g/ml in obese children. Leptin levels averaged 37.6 nanograms per milliliter (ng/ml) in obese children and 8.5 ng/ml in normal-weight children. ESR in normal-weight children was 9.5 millimeters per hour (mm/hr) and 21.7 mm/hr in obese children. Total cholesterol averaged almost 17 milligrams per deciliter (mg/dL) higher in obese children compared to normal-weight children.

Hassink said the research on 71 children is "just a pilot study." But if larger studies confirm the findings, she said doctors may initiate lifestyle and medical interventions in this "at-risk group" long before early signs of heart disease.

Researchers have not yet identified drugs that affect adiponectin, she said. Weight loss may increase adiponectin levels. Co-authors are Darlise O'Conor, Susan Kirwin, Joe Glutting and Vicky Funanage.

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Contact: Carole Bullock
carole.bullock@heart.org
214-706-1279
American Heart Association
5-Mar-2004

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