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Metabolic syndrome associated with cognitive decline in elderly persons

668 participants who had the metabolic syndrome and low inflammation did not show an increased likelihood of impairment. Also, those with the metabolic syndrome and high inflammation had greater four-year decline in cognitive testing scores than those without the metabolic syndrome, while those with the metabolic syndrome and low inflammation did not.

"To our knowledge, this is the first study to document that the metabolic syndrome is associated with poor cognitive outcomes," the researchers write. "Future studies will need to address whether preventing the metabolic syndrome or lowering inflammation prevents cognitive impairment in elderly individuals."


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Contact: Jennifer O'Brien
415-476-8432
JAMA and Archives Journals
9-Nov-2004


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